The Structural Basis of Membrane Function

1st Edition - January 1, 1976
Editor: Youssef Hatafi
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 4 8 0 2 - 3

The Structural Basis of Membrane Function is a documentation of an international symposium of the same title. This book serves as a collection of the significant articles… Read more

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The Structural Basis of Membrane Function is a documentation of an international symposium of the same title. This book serves as a collection of the significant articles pertaining to the field of membrane research. It is composed of seven parts, where the first and last parts are articles contributed by scientific authorities. The book generally discusses the membrane research and this study’s relevance to the society. Then, the book specifically looks into membrane features, including its structure, processes in it, functions, and types. Some of the specific topics included in the discussion of each part are phospholipases and monolayers used in studies of membrane structure; molecular aspects of active transport; and electron-transfer in energy-transducing membranes. The book also explains the two functions in common of biological membranes; synaptic receptor proteins; and liver microsomal membranes. The scope of this book is broad and helpful to many fields of scienec. It will be of great benefit to students, teachers, scientists, and researchers in the field of biochemistry, biology, molecular biology, chemistry, pharmacology, and cellular biology among others.

List of Contributors

Foreword

Preface

I IUB Lecture

Science and the Developing Nations

II Membrane Structure

Membrane Structure: Introductory Remarks

Phospholipases and Monolayers as Tools in Studies on Membrane Structure

The Structure of an Ion Pump

Structure and Biosynthesis of Mitochondrial Cytochromes in Baker's Yeast

The Lateral Organisation of Lipids Around a Calcium Transport Protein: Evidence for a Phospholipid Annulus that Modulates Function

Role of Adenine Nucleotides in the Structure and Function of the ATPase of the Inner Mitochondrial Membrane

III Transport in Membranes

Pathways and Stoichiometry of H+ and Ca2+ Transport Coupled to Electron Transport

Glutathione, 7-Glutamyl Transpeptidase, and the 7-Glutamyl Cycle in Amino Acid Transport

Molecular Aspects of Active Transport

The Active Extrusion of Weak and Strong Electrolytes in Intact Mitochondria

Ion Transport Through the Gramicidin A Channel

IV Energy Transduction in Membranes

Energy Transduction in Membranes

Recent Advances on the Chemistry of the Mitochondrial Oxidative Phosphorylation System

Probes of Energy Input in ATP Formation by Oxidative Phosphorylation

Biochemical Genetics of Oxidative Phosphorylation

On the Mechanism of Electron Flow and Charge Separation in the Ubiquinone-Cytochrome c Span of the Respiratory Chain

Energy Transduction in Isolated Chloroplast Membranes

V Regulatory Functions of Membranes

Membrane Structure in Relation to the Principle of Energy Transduction and to the Principle Underlying the Control of Membrane Function

Aldosterone-Mediated Changes in Lipid Metabolism in Relationship to Na+ Transport in the Amphibian Urinary Bladder

Cholera Toxin, Membrane Glycolipids, and the Mechanism of Action of Peptide Hormones

Mechanism of Carrier Transport and the ADP, ATP Carrier

The Regulation of Muscle Function by the Tropomyosin-Troponin System

VI Excitable Membranes

Organisation of the Sodium Channels in Excitable Membranes

Synaptic Receptor Proteins and Chemical Excitable Membranes

Agonist-Antagonist Discrimination by Solubilized Acetylcholine Receptor

VII Microsomal and Related Membranes

Thermodynamic Control Features of the Pseudomonas putida Monoxygenase System

The Metabolism of Polycyclic Hydrocarbons and Its Relationship to Chemical Carcinogenesis

Liver Microsomal Membranes: Reconstitution of the Hydroxylation System Containing Cytochrome P-450

The Microsomal Membrane: A Seraglio for Unique Electron Transport Carriers

Membrane Association of Steroid Hydroxylases in Adrenal Cortex Mitochondria

VIII Summary of the Symposium