The Sepsis Codex

The Sepsis Codex

1st Edition - November 30, 2022

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  • Editors: Marcio Borges, Jorge Hidalgo, Javier Perez-Fernandez
  • Paperback ISBN: 9780323882712

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Offering a global, multidisciplinary perspective on this life-threatening medical emergency, The Sepsis Codex provides a concise yet comprehensive look at a complex topic. Nearly 20% of global deaths are attributed to sepsis annually, nearly half of which are in children under the age of five, with low-resource settings being disproportionately affected. A “one size fits all” approach is not sufficient to meet individual patients’ needs, instead requiring a therapeutic approach that considers different ages, predisposing factors, genetic traits, and more. This cutting-edge resource brings you up to date with recent medical advances in this challenging area.

Table of Contents

    1 Sepsis: Past, Present, and Futured Lessons From COVID-19
    José-Artur Paiva and Jordi Rello
    2 Sepsis Definitions: A Historical Perspective
    Javier Perez-Fernandez, Arlene C. Torres, and Paola Perez
    3 The Epidemiology of Sepsis
    Jamila Hedjal
    4 Sepsis Pathophysiology
    Jorge Hidalgo, Maria Jimena Aleman, Luisa Cruz and Allyson Hidalgo-Morazan
    5 Sepsis and Microcirculation
    Carlos Enrique A. Orellana Jimenez
    6 Genetics and Sepsis
    Gabriela Alvarado
    7 Early Detection and Screening
    Márcio Borges Sá and Rafael Zaragoza Crespo
    8 Diagnosis and Monitoring of Sepsis
    Pietro Arina and Mervyn Singer
    9 Sepsis: Molecular Diagnostics and Biomarkers
    John Lyons and Craig Coopersmith
    10 Hemodynamic Monitoring: Current Practice and New Perspectives
    Christopher Lai and Jean-Louis Teboul
    11 Point of Care Ultrasound in the Management of Sepsis
    Saad Mahdy, Ahmed F. Hegazy and Tharawt Aisa
    12 New Approaches and Understanding of Sepsis
    Vanessa Fonseca-Ferrer, Sulimar Morales-Colón, Luis Gerena-Montano, William
    Rodríguez-Cintrón, and Gloria M. Rodríguez-Vega
    13 Sepsis Quality Indicators in the Emergency Department
    Luis Antonio Gorordo-Delsol and Graciela Merinos-Sánchez
    14 Sepsis Treatment: Fluids
    Michaël Mekeirele, Domien Vanhonacker and Manu L.N.G. Malbrain
    15 Vasopressor Therapy in Septic Shock
    Rajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa
    16 Mechanical Ventilation in Sepsis
    Carlos Sánchez, Orlando Pérez-Nieto and Eder Zamarrón
    17 Extracorporeal Membrane Oxygenation for the Support of Patients With Refractory Septic Shock
    Jose Alfonso Rubio Mateo-Sidron
    18 Antimicrobials in the Management of Sepsis
    Judith Jacobi
    19 Kidney Support in Sepsis
    Javier Maynar, Helena Barrasa, Alex Martin and Fernando Fonseca
    20 Hematological Support in Sepsis
    Zulmi Aranda, Gerhaldine Morazan and Allyson Hidalgo
    21 Specific Treatment of Focus Control in Sepsis
    Xavier Guirao, Montserrat Juvany, Clara Centeno and Josep Maria Badia
    22 Sepsis Adjunctive Therapies
    Javier Perez-Fernandez and Paola Perez
    23 Glycemic Control and Stress Ulcer Prophylaxis
    Janice L. Zimmerman
    24 Nutrition in Sepsis
    Victor Sanchez Nava

    25 Fever in Intensive Care Units
    Kazuaki Atagi
    26 Sepsis--In the Era of Antimicrobial Resistance
    Rajesh Chandra Mishra, Sharmili Sinha, Reena Shah, Ahsan Ahmed and Ahsina Jahan Lopa
    27 Factors Underlying Racial and Gender Disparities in Sepsis Management
    Ryoung-Eun Ko and Gee Young Suh
    28 Sepsis in Special Populations
    Marie Baldisseri, Laura S. Johnson, Michael Mazzei and Mary Jane Reed
    29 Comprehensive Management of Sepsis in Pediatrics
    Elisabeth Esteban, Juan Carlos de Carlos, Juan Ignacio Sánchez and Javier Gil Anton
    30 Maternal Sepsis
    Luis Antonio Gorordo-Delsol, Graciela Merinos- Sánchez, Lucina Nieves-Torres and Jeanette Zúñiga Escorza
    31 Role of Preventive Measures in Sepsis
    Jorge Sinclair, Jorge E. Sinclair De Frías and Lorenzo Olivero
    32 Value of the Protocolization and Sepsis Performance Improvement Program in Early Identification
    Carlos Sanchez
    33 Long-Term Sequelae of Sepsis
    Ahmed Taha
    34 New Diagnostic and Therapeutic Perspectives
    Juan Carlos Ruiz-Rodríguez, Luis Chiscano-Camón, Erika-Paola Plata Menchaca and Ricard Ferrer
    35 Artificial Intelligence in Sepsis
    Michiel Schinkel, Ketan Paranjape, Prabath W.B. Nanayakkara and W. Joost Wiersinga

Product details

  • No. of pages: 362
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: November 30, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780323882712

About the Editors

Marcio Borges

Affiliations and Expertise

Associate Professor of Infectious Disease Balearic Islands University; Coordinator, Multidisciplinary Sepsis Unit, Critical Care Medicine, Son Llatzer University Hospital, Palma de Mallorca, Spain

Jorge Hidalgo

Dr. Jorge Hidalgo is a Professor of Critical Care and the Head of the Division of Critical Care at Karl Heusner Memorial Hospital in Belize, Central America. He is the President Elect of the World Federation of Societies of Critical Care and Intensive Care Medicine. He has won several awards with the highest recognition and the Director of the very prestigious ACP Review Course hosted by the Paraguay Society of Internal Medicine. Due to his outstanding contribution to the Society of Critical Care Medicine he received the Presidential Citation Award. And Global Safar Award, becoming the First Latin American Intensivist to get this Nomination. He is involved in numerous congresses and a well-recognized international speaker.

Affiliations and Expertise

Professor of Critical Care and the Head of the Division of Critical Care, Karl Heusner Memorial Hospital in Belize, Central America. President Elect, World Federation of Societies of Critical Care and Intensive Care Medicine.

Javier Perez-Fernandez

Dr. Javier Perez-Fernandez serves as Medical Director of the Critical Care Services at Baptist Hospital of Miami. He is a Clinical Associate Professor of Medicine at Florida International University, Herbert Wertheim College of Medicine and Professor Pulmonary and Critical Care Medicine at Larkin University, Miami-Dade Florida. He is the Secretary-General of the World Federation of Intensive Care. Dr. Perez-Fernandez manages a large group of critical care physicians, South Florida Critical Care Services, overseeing the operations of seven ICUs with over 350 beds. He has been a regional and national recognized leader during the COVID-19 pandemic with multiple TV and media appearances and consulting services for several national and international organizations. He has been directly involved in the development of Rapid Response Teams, technology implementation and “open ICU” models. He has lectured worldwide and author of many original publications with the Society of Critical Care Medicine.

Affiliations and Expertise

Medical Director, Critical Care Services Baptist Hospital of Miami, Florida, USA

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