The Role of Chromosomes in Development - 1st Edition - ISBN: 9780123957276, 9780323156851

The Role of Chromosomes in Development

1st Edition

Editors: Michael Locke
eBook ISBN: 9780323156851
Imprint: Academic Press
Published Date: 1st January 1964
Page Count: 302
Tax/VAT will be calculated at check-out Price includes VAT (GST)
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
54.95
38.47
38.47
38.47
38.47
38.47
43.96
43.96
43.99
30.79
30.79
30.79
30.79
30.79
35.19
35.19
72.95
51.06
51.06
51.06
51.06
51.06
58.36
58.36
Unavailable
Price includes VAT (GST)
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

The Role of Chromosomes in Development is a collection of papers presented at the 23rd Symposium of the Society for the Study of Development and Growth, held at Amherst, Massachusetts in June 1964. Contributors explore the role of chromosomes in development, highlighting important processes such as the diversification and specialization of cells; the regulation of gene function by the physical state of the chromosome; the functional organization of chromosomes; DNA replication and synthesis; and macronuclear differentiation and subnuclear assortment.
This volume is organized into 11 chapters and begins with an overview of chromosome structure and function and the mechanisms underlying the role of the chromosome in embryonic development. This book then discusses the chromosomal DNA replication, the mechanisms of gene modulation, the binding of actinomycin to DNA, and the cytological aspects of DNA replication in higher animals. The next chapters explain localized DNA synthesis in polytene chromosomes; chromosomal RNA and other nuclear RNA fractions; and experimental work probing both genetic and functional mosaicism in the mouse, as well as genetic repression of the R locus in maize. The book also considers how developmental pathways are controlled by genetic mechanisms, and then concludes with a chapter on nuclear differentiation in ciliates and on the phenomenon of subnuclear assortment.
This book will be of interest to developmental biologists and embryologists.

Table of Contents


Contributors and Presiding Chairmen

Dedication

The Role of Chromosomes in Development

Text

References

Structural Patterns and the Functional Organization of Chromosomes

Replication

Repository Function

Variation

Discussion and Summary

References

Chromosomal Proteins

Proteins and Chromosome Structure

The Acidic Nuclear Proteins

The Acidic Proteins and Gene Modulation

The Histones and Gene Modulation

Structure of the N-Proline Histone

Mechanisms of Gene Modulation

Functional State of the Genome

Summary

References

Binding of Actinomycin as a Model for the Complex-Forming Capacity of DNA

Text

References

DNA Replication Sequences in Higher Animals

Introduction

Materials and Methods

The Relationship between Heteropyknosis, Gene Inactivation, and DNA Replication

The Terminal Stages of DNA Replication

Late Replication and Metaphase Chromosome Morphology

The Commencement of DNA Replication

Quantitative Autoradiography of Chromosomes

Discussion

References

Localized DNA Synthesis in Polytene Chromosomes and Its Implications

Text

References

Chromosomal RNA and Other Nuclear RNA Fractions

Chromosomal RNA

Nucleolar RNA

Nuclear Sap RNA

Summary

References

Genetic and Functional Mosaicism in the Mouse

Genetic Mosaicism

Functional Mosaicism

Summary

References

Genetic Repression of R Action in Maize

Experimental Materials and Methods

Paramutation of Rr in RrRst and Rrrr Heterozygotes

Partial Reversion of Paramutant R

Changes in Action of Rr and R9 Alleles from Stock Cultures in Heterozygotes with Each Other

Acquisition of Paramutagenicity by Rr in Stippled Hétérozygotes

Association of the R Locus with Paramutation

Continuous Variation in Paramutation

Compound Nature of the Stippled Allele

Progressive Paramutation in Successive Generations

Occurrence of Paramutation in Somatic Cells

Manifestation of Paramutation in Sporophytic Tissues

The Origin and Geographic Distribution of Paramutable and Nonparamutable R Alleles

R Action in Structurally Altered Chromosome 10

Paramutability of Rr When Carried by Chromosome K10

Level of R Action in Relation to Mode of Sexual Transmission

Effects on Rr and Rst of High Energy Irradiation

Is a Gene-Dependent Cytoplasmic Particle Associated with R Paramutation?

Paramutation in Other Organisms

Summary and Discussion

References

Genetic Control and Regulation of Developmental Pathways

Introduction

Genetic Methods for the Analysis of Development

The Bithorax Pseudoallelic Series

Developmental Effects of the Bithorax Mutants

Gene Dosage Studies

Somatic Mosaics

Cis-Trans Effects

The Trans-Vection Effect

Discussion

Summary

References

Macronuclear Differentiation and Subnuclear Assortment in Ciliates

Morphological Nuclear Differentiation

Caryonidal Distribution: Mating Type Differentiation in Syngen 1, Paramecium aurelia

Subnuclear Assortment: Mating Type Differentiation in Syngen 1, Tetrahymena pyriformis

Subnuclear Assortment: Allelic Repression or Hétérozygote Resolution?

Conclusion

References

Author Index

Subject Index


Details

No. of pages:
302
Language:
English
Copyright:
© Academic Press 1964
Published:
Imprint:
Academic Press
eBook ISBN:
9780323156851

About the Editor

Michael Locke