The Role of Chromosomes in Cancer Biology provides a description of the molecular organization and function of chromosomes and the consequences of chromosomal aberrations in human development. The book presents accounts on the structure and function of the chromosome; the cellular features of primary tumors and ascetic fluid; the cytological actions of radiation and drugs and their relevance to therapy. Developmental disorders caused by chromosomal anomalies; chromosome aneuploidy in human malignancies; and viral oncogenesis are discussed as well. The book will prove to be very insightful to those involved in cancer research, oncologists, cytologists, and molecular biologists.
Chapter 1 Chromosome Structure and Function Summary Chapter 2 Chromosomal Anomalies as the Cause of Developmental Disorders1. Numerical Changes 2. Structural Changes 3. Chromosome Anomalies in the Fetus 4. Chromosomal Mosaicism Summary
Chapter 3 Mitotic Anomalies in Tumors and Boverts Theory Summary Chapter 4 Malignant Cell Populations and the Stemline Concept Summary Chapter 5 Chromosomal and Functional Differences in Malignant Cell Populations Summary Chapter 6 Primary Tumors in Animals1. "Spontaneous" Primary Tumors 2. Induced Primary Tumors Summary
Chapter 7 Chromosome Aneuploidy in Human Malignancies: Effusions Summary Chapter 8 Chromosome Aneuploidy in Human Malignancies: Solid Tumors Summary Chapter 9 Marker Chromosomes and the Clonal Evolution of Chromosome Aberrations Summary Chapter 10 Chromosomes in Precancerous Lesions and in Tumor Development Summary Chapter 11 Chromosomal Predisposition to Cancer Summary Chapter 12 Chromosomes and Viral Oncogenesis Summary Chapter 13 Chromosomes and the Treatment of Cancer Summary Conclusion References Subject Index
- No. of pages:
- © Butterworth-Heinemann 1972
- 1st January 1972
- eBook ISBN: