The Retina: A Model for Cell Biology Studies, Part II, is the second of a two-part series that details developments in the study of retinal cell biology.
The book begins with a review of the current evidence for the role of putative neurotransmitters at particular synapses in the retina. It then discusses pre- and postsynaptic regulatory mechanisms; the interactions of neurotransmitter-neuromodulatory systems; and cellular effects of putative neurotransmitters and neuromodulators. This is followed by an introduction to vision psychophysics, showing its application in studying the functioning of cells in the retina. The remaining chapters discuss how the retinal pigment epithelium cell might be used as a model for studying biological problems of current interest; extracellular matrix molecules; concepts and controversies regarding the biology of endothelial cells, the key elements in the phenomenon of intraocular neovascularization; the use of genetic mutations and genetic mosaics for the study of the retina; and the retina as a regenerating organ.
Contributors Preface Neurotransmitters and Neuromodulators in the Retina: Regulation, Interactions, and Cellular Effects I. Introduction II. Putative Neurotransmitters and Neuromodulators of Retinal Neurons III. Pre- and Postsynaptic Regulatory Mechanisms IV. Interactions of Neurotransmitters and Neuromodulators V. Cellular and Morphological Effects of Neurotransmitters and Neuromodulators VI. Concluding Remarks References Vision Psychophysics and Retinal Cell Biology I. Introduction II. The Systems Approach of Psychophysics III. Psychophysical Studies of Photoreceptor Physiology IV. Psychophysical Studies of Abnormal Retinal Physiology in Retinitis Pigmentosa V. Retinal Cell Biology from a Psychophysicist's Perspective References The Cell Biology of the Retinal Pigment Epithelium I. Summary of RPE Cell Structure and Functions II. Cellular Processes That Have Been Studied in the RPE III. Use of Cultured RPE Cells to Study Cellular Processes IV. Summary and Future Research References Extracellular Matrix Molecules: Their Importance in the Structure and Function of the Retina I. Introduction II. Extracellular Matrices III. Retinal Extracellular Matrices IV. Effects of Extracellular Matrix Molecules on Retinal Neurons V. Concluding Comments References Cell Biology and Biochemistry of Endothelial Cells and the Phenomenon of Intraocular Neovascularization I. Introduction II. New Vessels from Preexisting Vessels III. Steps in Capillary Formation IV. Maturation of the Vascular Bed V. Factors Influencing Capillary Sprout Formation VI. Conclusion References Genetic Mosaics as Tolls for the Study of the Retina I. A Modest Catalog of Known Mutations Affecting the Eye II. Genetic Mosaics: A Primer III. The Study of the Site of Gene Action IV. The Study of Cell Line
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- © Academic Press 1986
- 12th May 1986
- Academic Press
- eBook ISBN: