The Retina A Model for Cell Biology Studies Part_1 - 1st Edition - ISBN: 9780120442751, 9780323140720

The Retina A Model for Cell Biology Studies Part_1

1st Edition

Editors: Ruben Adler
eBook ISBN: 9780323140720
Imprint: Academic Press
Published Date: 28th April 1986
Page Count: 380
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The Retina: A Model for Cell Biology Studies, Part I, is the first of a two-part series that details developments in the study of retinal cell biology. The book begins with some basic information about retinal structure and development followed by a discussion of the advantages of the retina as a model system for cell biology studies. It reviews some of the major events in the maturation of the retina pertinent to the assembly of neuronal circuits. The book describes studies of neuronal assembly in order to demonstrate that adhesion-based neuronal assembly may be the most elaborated example of a wider class of morphogenetic phenomena categorized as ""adhesion-guided multicellular assembly"" systems. The remaining chapters discuss in vivo and in vitro studies on trophic interactions in retinal development and in retinal degenerations; cell motility in the retina; molecular properties of vertebrate rod cells; the role of cyclic nucleotides in the metabolism and function of the retina; and the cellular and molecular aspects of photosensitive membrane turnover.

Table of Contents

Contributors Preface Issues and Questions in Cell Biology of the Retina I. Introduction II. The Adult Retina III. The Developing Retina IV. The Pathological Retina V. Concluding Remark References The Development of Retinal Networks I. Introduction II. The Development of Retinal Layers III. Neurochemical Differentiation in the Retina IV. Maturation of Retinal Networks V. Summary References Differential Adhesion in Neuronal Development I. Introduction II. Neuronal Guidance Systems: Biological Studies III. Molecular Mechanisms of Adhesion IV. Neuronal Recognition and Differential Adhesion References Trophic Interactions in Retinal Development and In Retinal Degenerations. In Vivo and In Vitro Studies I. Introduction II. The Regulation of Neuronal Survival III. The Search for "Trophic" and Other Regulatory Factors IV. The Search for Molecules Controlling Survival and Differentiation of Retinal Neurons: In Vitro Studies V. Concluding Remarks References Cell Motility in the Retina I. Introduction II. The Structural Machinery: The Cytoskeleton III. Force-Producing Mechanisms IV. Vertebrate Retinomotor Movements V. Invertebrate Retinomotor Movements VI. Cytoskeleton and Motility in RPE Cells VII. Morphological Aspects of Retinal Synaptic Modulation VIII. Alignment of Photoreceptors IX. Concluding Remarks References Molecular Dynamics of the Rod Cell I. Structure of the Rod Cell II. Disk Membrane of the Rod Cell Outer Segment III. Rhodopsin: The Photoreceptor Protein IV. Light-Dependent Biochemistry of the Rod Cell References Cyclic Nucleotides in Retinal Function and Degeneration I. Introduction II. Cyclic Nucleotide Metabolism in Rod-Dominant Retinas III. Cyclic Nucleotides in Cone-Dominant Retinas IV. Abnormalities i


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© Academic Press 1986
Academic Press
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About the Editor

Ruben Adler

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