The Pulmonary Circulation in Health and Disease

The Pulmonary Circulation in Health and Disease

1st Edition - January 28, 1987

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  • Editor: James Will
  • eBook ISBN: 9780323145237

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The Pulmonary Circulation in Health and Disease covers the proceedings of a symposium purposed to create a more complete picture of the pulmonary circulation under normal and diseased conditions through the help of an interdisciplinary group of acknowledged experts. The book is divided into seven parts. The first part discusses morphology in relation to pulmonary circulation and includes an overview of the microscopic appearance of the pulmonary artery and the innervation of the pulmonary circulation, as well as the structure and infrastructure of the pulmonary microvasculature and the changes it undergoes. The second part concerns itself with the different pharmacological studies related to pulmonary circulation. The third part goes in-depth about concepts in pulmonary hemodynamics, such as its occlusion methods, its models based on anatomic and functional data, its active distribution, and gravity nondependent distribution of pulmonary blood flow; the fourth part on the other hand discusses pulmonary blood flow and gas exchange. The fifth part discusses pulmonary endothelial cells, its mechanisms, and its properties; the sixth and seventh parts cover the mechanisms of pulmonary hypertension. The text is recommended for basic scientists studying the lung and for clinicians such as cardiologists and pulmonologists. Those interested in the effects of alterations in lung function will also find this helpful.

Table of Contents

  • Contents




    An Overview of the Microscopic Appearance of the Pulmonary Artery and the Problems of Its Quantitation

    Innervation of the Pulmonary Circulation: An Overview

    The Pathology of Human Pulmonary Hypertension Pattern Recognition and Specificity

    The Structure and Ultrastructure of the Pulmonary Microvasculature

    The Pulmonary Vasculature and Experimental Pulmonary Hypertension in Animals

    Pulmonary Vascular Changes in Infants and Children

    Summary: The Morphology of the Pulmonary Vasculature


    Pharmacology of the Pulmonary Circulation: Introduction

    Pharmacology of the Pulmonary Circulation: An Overview

    Vascular Smooth Muscle Metabolism and Mechanisms of Oxygen Sensing

    Pharmacological Studies of Contractile and Relaxant Responses to Serotonin in Extralobar Pulmonary Arteries Isolated from the Guinea Pig

    Pulmonary Vascular Responses to Eicosanoids

    Relationship of Pharmacologic Agents, Pulmonary Endothelial cells and Pulmonary Circulation

    Pharmacology of the Pulmonary Circulation: Summary


    Pulmonary Hemodynamics: Introduction

    Pulmonary Microvascular Hemodynamics: Occlusion Methods

    Models of the Pulmonary Hemodynamics Based on Anatomic and Functional Data

    Interpretation of Pressure-Flow Curves in the Pulmonary Vascular Bed

    Gravity Nondependent Distribution of Pulmonary Blood Flow

    Active Regulation of the Pulmonary Circulation: A Model for Hypoxic Pulmonary Vasoconstriction

    Pulmonary Hemodynamics: Summary

    Pulmonary Blood Flow and Gas Exchange

    Pulmonary Blood Flow and Gas Exchange: Introduction

    Pulmonary Blood Flow and Gas Exchange: An Overview

    Gas Exchange in Pulmonary Vascular Disease

    Pulmonary Circulation in Exercise

    Effects of Hypoxic Vasoconstriction on the Mechanical Interaction between Pulmonary Vessels and Airways

    Vasomotor Tone and Optimization of Gas Exchange

    Endothelial Function

    The Pulmonary Endothelium: Summary

    Pulmonary Endothelial Cells

    Mechanisms of Lung Endothelial Injury

    Regulation of Transport and Permeability Properties of Pulmonary Endothelium

    Interactions of Anaphylatoxins with Endothelium

    Hemostatic Potential of the Pulmonary Endothelium

    Mechanisms of Pulmonary Hypertension

    Mechanisms of Pulmonary Hypertension, 1986: Introduction

    Mechanisms of Pulmonary Hypertension: An Overview

    Pulmonary Hypertension in the Presence of High Blood Flow

    Persistent Pulmonary Hypertension Syndromes in the Newborn

    Potential Mechanisms of Hypoxic Pulmonary Vasoconstriction

    Mechanisms of Control of the Perinatal Pulmonary Circulation


    Clinical Pulmonary Hypertension

    Clinical Pulmonary Hypertension: Introduction

    Clinical Pulmonary Hypertension: An Overview

    Epidemiologic and Clinical Characteristics of Primary Pulmonary Hypertension

    Diagnosis and Long-Term Management of Venous Thromboembolism

    Management of Chronic Unresolved Large Vessel Thromboembolism

    Exogenous Influences on the Initiation and Course of Pulmonary Hypertension


Product details

  • No. of pages: 584
  • Language: English
  • Copyright: © Academic Press 1987
  • Published: January 28, 1987
  • Imprint: Academic Press
  • eBook ISBN: 9780323145237

About the Editor

James Will

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