The Pituitary
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The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors. Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders.
Key Features
- Provides a detailed description of the wide spectrum of clinical disorders emanating from the dysfunction of the “master gland” and the fundamental science underlying pituitary dysfunction
- Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches
- Describes the mechanisms for disease pathogenesis, including both subcellular and extrinsic mechanisms that subserve normal and disordered pituitary hormone secretion and action
Readership
Researchers, practitioners, and graduate students in endocrinology and researchers of endocrine diseases across biomedical disciplines, as well as those working with endocrinologists such as neurosurgeons and OB/GYNs
Table of Contents
- 1. Pituitary Development
2. Hypothalamic Regulation of Anterior Pituitary Function
3. Adrenocorticotropin
4. Growth Hormone
5. Prolactin
6. Thyroid-stimulating Hormone
7. Gonadotropin Hormones
8. The Posterior Pituitary
9. The Hypothalamus
10. Anterior Pituitary Failure
11. Pituitary-Immune Interface
12. Pituitary Function in Systemic Disorders
13. Drugs and Pituitary Function
14. The Pituitary Gland in Pregnancy
15. Acromegaly
16. Prolactinoma
17. Cushing's Disease
18. Non-functioning and Gonadotroph Tumors
19. Thyrotropin-Secreting Pituitary Tumors
20. Aggressive Pituitary Adenomas
21. Genetics of Pituitary Tumor Syndromes
22. Nonpituitary Sellar Masses
23. Pituitary Imaging
24. Pituitary Surgery
25. Pituitary Radiotherapy
Product details
- No. of pages: 790
- Language: English
- Copyright: © Academic Press 2022
- Published: June 1, 2022
- Imprint: Academic Press
- Hardcover ISBN: 9780323998994
About the Editor
Shlomo Melmed
Shlomo Melmed, MB, ChB, FRCP, MACP, is Executive VP and Dean of the Medical Faculty at Cedars-Sinai Medical Center. He leads Cedars-Sinai’s research and education programs, recruiting nationally recognized faculty leadership, establishing new educational programs and maintaining the highest academic standards. Dr. Melmed holds the Helene A. and Philip E. Hixon Distinguished Chair in Investigative Medicine. An international authority on pituitary medicine, he has pioneered the discovery and application of novel treatments for endocrine tumors and has authored more than 350 peer-reviewed articles.
Dr. Melmed has been a faculty leader at Cedars-Sinai for nearly 40 years and has been the health system’s chief academic officer since 1998. Dr. Melmed's laboratory consistently has received competitive grant awards from the National Institutes of Health since 1980, and he has trained over 80 physicians, scientists and graduate students who occupy leading positions in academic endocrinology worldwide. He is on the editorial board of the Journal of Clinical Investigation and is also an Associate Dean of the UCLA School of Medicine.
Affiliations and Expertise
Professor of Medicine, Dean of the Medical Faculty, Cedars Sinai Health System, USA