The Pharmacological Potential of Cyanobacteria

The Pharmacological Potential of Cyanobacteria

1st Edition - January 19, 2022

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  • Editors: Graciliana Lopes, Marisa Silva, Vitor Vasconcelos
  • Paperback ISBN: 9780128214916
  • eBook ISBN: 9780128214923

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The Pharmacological Potential of Cyanobacteria explores the bioactive compounds isolated from cyanobacteria and their relationship to human health and biotechnological applications. The book presents an overview of the chemistry and ecology of cyanobacteria, focusing on culture needs and techniques of biomass production. It is organized according to the different biological activities and biotechnological applications of compounds discovered in recent years. Besides biological activity, the mechanism of action of compounds is explained, along with molecular structure. Finally, compounds already used in therapeutics and biotechnology, as well as those in phases of approval or clinical trials are explored. Each chapter is written by a different research group with expertise in the field and publications in peer reviewed journals. Researchers and students in pharmaceutical academic research, pharmaceutical industrial sector personnel, health professionals, and nutritionists will find this book to be very useful.

Key Features

  • Covers all the bioactive compounds of cyanobacteria discovered thus far
  • Includes chapters by experts in the field, covering the chemistry and mechanisms of action of cyanobacteria-bioactive compounds
  • Provides a general overview of organisms, from biomass production to compound isolation and evaluation of bioactivities in different cell and cell-free systems


Scientists developing their research in the field of cyanobacteria, especially in the structure elucidation of new compounds with interest for human health, and in the biotechnological applications of these organisms. Advanced students and academic researchers in the disciplines of Biology, Biochemistry and Phytochemistry

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • List of Contributors
  • Preface
  • Chapter 1. Trends in Cyanobacteria: a contribution to systematics and biodiversity studies
  • Abstract
  • 1.1 General aspects of Cyanobacteria
  • 1.2 Cyanobacteria biodiversity
  • 1.3 Classification systems and future challenges for Cyanobacteria taxonomy
  • References
  • Chapter 2. Specialized metabolites from cyanobacteria and their biological activities
  • Abstract
  • 2.1 Introduction
  • 2.2 Secondary metabolites isolated from cyanobacteria
  • Acknowledgments
  • References
  • Chapter 3. Cyanobacterial anticancer compounds in clinical use: Lessons from the dolastatins and cryptophycins
  • Abstract
  • 3.1 Introduction
  • 3.2 Cyanobacterial compounds in clinical trials
  • 3.3 Discussion
  • 3.4 Concluding remarks
  • Acknowledgments
  • References
  • Chapter 4. Anti-inflammatory compounds from cyanobacteria
  • Abstract
  • 4.1 Introduction
  • 4.2 Inflammatory process—general overview
  • 4.3 Cyanobacteria as source of anti-inflammatory compounds
  • 4.4 Applicability of cyanobacterial compounds as anti-inflammatory agents
  • 4.5 Final remarks
  • Acknowledgments
  • References
  • Chapter 5. UV-protective secondary metabolites from cyanobacteria
  • Abstract
  • 5.1 Introduction
  • 5.2 Scytonemins
  • 5.3 Mycosporine-like amino acids of cyanobacteria
  • 5.4 Future perspectives on scytonemins and mycosporine-like amino acids
  • 5.5 Other potentially UV-protective compounds
  • References
  • Chapter 6. Antimicrobial activity of Cyanobacteria-derived compounds
  • Abstract
  • 6.1 Introduction
  • 6.2 Antibiotic resistance crisis and impact
  • 6.3 Cyanobacteria as a promising source for antibiotic discovery
  • 6.4 Recent studies in antimicrobial activity of Cyanobacteria
  • 6.5 Perspectives and novel technologies for antimicrobial study in Cyanobacteria
  • 6.6 Conclusions
  • Acknowledgments
  • References
  • Chapter 7. The role of toxins: impact on human health and aquatic environments
  • Abstract
  • 7.1 Bloom definition and toxin biologic role
  • 7.2 Cyanotoxins
  • 7.3 Cyanotoxin impacts
  • Acknowledgments
  • References
  • Chapter 8. Cyanobacterial pigments: photosynthetic function and biotechnological purposes
  • Abstract
  • 8.1 Introduction
  • 8.2 Biotechnological uses of cyanobacterial pigments
  • 8.3 Cyanobacterial pigment production—approaches and biotechnological perspectives
  • 8.4 Conclusions
  • Acknowledgments
  • References
  • Chapter 9. Cyanobacteria in cosmetics: a natural alternative for anti-aging ingredients
  • Abstract
  • 9.1 General introduction
  • 9.2 Cyanobacteria in cosmetics
  • 9.3 Conclusions
  • Acknowledgments
  • References
  • Chapter 10. The nutraceutical potential of cyanobacteria
  • Abstract
  • 10.1 Introduction
  • 10.2 Cyanobacteria production methods
  • 10.3 Cyanobacteria as food supplements
  • 10.4 Spirulina
  • 10.5 Klamath
  • 10.6 Nostoc
  • 10.7 Cyanobacteria and micropathogens out of control
  • 10.8 Microalgae as food supplements
  • 10.9 Conclusions
  • References
  • Index

Product details

  • No. of pages: 356
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: January 19, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780128214916
  • eBook ISBN: 9780128214923

About the Editors

Graciliana Lopes

Graciliana Lopes is a pharmacist, with specialization in Phytochemistry and Pharmacognosy, and with a strong background in biological assays in cell and cell-free systems, and mechanisms of action of drugs. Her research has been most devoted to the fields of inflammation, microbiology, oxidative stress and chromatography.

Affiliations and Expertise

CIIMAR – Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Novo Edifício do Terminal de Cruzeiros de Leixões, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal

Marisa Silva

Marisa Silva is a Biologist has a strong background in marine toxins and in chromatographic techniques, with emphasis on LC-MS/MS. Her research contributed to the update of EFSA’s recommendations regarding emergent marine toxins monitoring and public health risk hazard.

Affiliations and Expertise

MARE - Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016, Lisbon, Portugal

Vitor Vasconcelos

Department of Biology the Faculty of Sciences , Porto University and the head of the Laboratory of Ecotoxicology, Genomics and Evolution (LEGE) at the Marine and Environmental Research Center (CIIMAR) of Porto University, Portugal

Affiliations and Expertise

Interdisciplinary Centre of Marine and Environmental Research (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4450-208, Matosinhos, Portugal Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Rua Campo Alegre s/n, 4169-007, Porto, Portugal

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