The Pathophysiology and Pharmacotherapy of Myocardial Infarction - 1st Edition - ISBN: 9780122380457, 9781483277141

The Pathophysiology and Pharmacotherapy of Myocardial Infarction

1st Edition

Editors: Nabil El-Sherif C. V. Ramana Reddy
eBook ISBN: 9781483277141
Imprint: Academic Press
Published Date: 28th January 1986
Page Count: 402
Sales tax will be calculated at check-out Price includes VAT/GST
54.95
72.95
43.99
Unavailable
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications.

This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock.

The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death.

This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

Table of Contents


Contributors


Preface


1. Pathogenesis of Coronary Atherosclerosis: Prevention of Atherogenesis


I. The Atherosclerotic Lesion


II. Pathogenesis of Atherosclerosis


III. Risk Factors in Atherogenesis


IV. Clinical Trials


V. Regression of Atheroma in Humans


VI. Regression of Atheroma in Experimental Animals


References


2. Hemodynamic Consequences of Myocardial Infarction and the Role of Vasodilators in Acute and Chronic Management


I. Introduction


II. Hemodynamic Consequences of Heart Failure


III. Potential Benefits of Vasodilators in Congestive Heart Failure


IV. Classification and Mechanisms of Vasodilation


V. Site of Action of the Vasodilators


VI. Vasodilator Agents: Pharmacology, Hemodynamics, and Side Effects


VII. Clinical Applications


VIII. Summary


References


3. Pump Failure: Role of Vasopressor Agents


I. Introduction


II. Pathophysiology


III. Role of Vasopressor Agents in the Treatment of Pump Failure


IV. Future Directions


References


4. Coronary Artery Spasm and Pharmacology of Coronary Vasodilators


I. Introduction


II. Coronary Artery Spasm: Evolution of Current Concepts


III. Coronary Artery Spasm and Myocardial Infarction


IV. Pathophysiological Mechanisms


V. Pharmacology of Coronary Vasodilators


VI. Summary


References


5. Physiologic Basis and Results of Thrombolytic Therapy in Acute Myocardial Infarction


I. Introduction


II. Physiology of Thrombus Formation and Fibrinolytic Enzyme System


III. Early Trials of Long-Duration, Late Intravenous Thrombolytic Therapy in Acute Myocardial Infarct

Details

No. of pages:
402
Language:
English
Copyright:
© Academic Press 1986
Published:
Imprint:
Academic Press
eBook ISBN:
9781483277141

About the Editor

Nabil El-Sherif

C. V. Ramana Reddy

Ratings and Reviews