Metabolic bone degeneration (osteoporosis) affects millions of people--primarily postmenopausal women--and is directly responsible for debilitating hip, vertebral, and limb fractures in the elderly. Incorporating advances made within just the past five years, The Osteoporotic Syndrome: Detection, Prevention, and Treatment serves as an up-to-date, practical guide to the major clinical aspects of osteoporosis. The text is liberally illustrated with detailed figures. As a resource for the clinician dealing with metabolic bone degeneration, this book represents an excellent source of information on the diagnosis and day-to-day management of osteoporosis.

Key Features

@introbul:Topics covered include @bul:* Therapy with Vitamin D metabolites, sodium fluoride, thiazides, and isoflavones * Biochemical markers of bone turnover * Calcium, Vitamin D, and bone metabolism * Estrogens and tissue selective estrogens for prevention and treatment of osteoporosis * The effects of osteoporosis on orthopaedic surgery * The therapy of glucocorticoid bone disease * Effects of aging on bone structure and metabolism * Management of osteoporotic patients in our health care delivery system * The genetics of osteoporosis * Bisphosphonate therapy for osteoporosis * Calcitonin * Bone mass measurement techniques in clinical practice * Osteoporosis and the bone biopsy


Professionals and academic clinicians in endocrinology, bone and mineral metabolism, and osteoporosis.

Table of Contents

Contents Contributors Preface 1. The Necessity of a Managed Care Approach for Osteoporosis 2. Effects of Aging on Bone Structure and Metabolism 3. The Genetics of Osteoporosis 4. Bone Mass Measurement Techniques in Clinical Practice 5. Biochemical Markers of Bone Turnover 6. Calcium, Vitamin D, and Bone Metabolism 7. Estrogens and Selective Estrogen Receptor Modulators for Prevention and Treatment of Osteoporosis 8. Bisphosphonate Treatment for Osteoporosis 9. Calcitonin Treatment in Postmenopausal Osteoporosis 10. Therapy with Vitamin D Metabolites, Sodium Fluoride, Thiazides, and Isoflavones 11. Orthopedics and the Osteoporotic Syndrome 12. Glucocorticoid-Related Osteoporosis 13. Osteoporosis and the Bone Biopsy Index


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© 2000
Academic Press
eBook ISBN:
Print ISBN:

About the editor

Louis Avioli

Dr. Louis V. Avioli, M.D. is widely regarded as the leading authority on osteoporosis and calcium metabolism. His distinguished career as a clinician, academician, and practicing endocrinologist covers more than 30 years of service. He is the founder and past president of the American Society for Bone and Mineral Research, and the founder and current president of the Association of Osteobiology. He is currently the Shoenberg Professor of Medicine, Professor of Orthopedic Surgery and director of the Division on Bones and Mineral Diseases at Washington University School of Medicine.

Affiliations and Expertise

Washington University, St. Louis, Missouri, U.S.A.