
The Orexin/Hypocretin System
Functional Roles and Therapeutic Potential
Description
Key Features
- Provides an overview of new research on orexins/hypocretins
- Includes an overview of intracellular signaling and orexin physiology
- Discusses the effects on arousal, appetite, cognition, addiction and anxiety
- Examines orexin based therapies and their potential use in disorders
- Explores orexin receptors for drug development
Readership
Table of Contents
Part 1: Introduction
1. Hypocretins (orexins): 20 years of dissecting arousal circuits
2. Orexins and motivated behaviorsPart 2: Orexins and Sleep
3. Orexins and the stabilization of wake/sleep states
4. Orexins and narcolepsy in animal modelsPart 3: Orexins and Feeding
5. Orexin’s role in motivated behavior for food
6. Orexin drives energy expenditurePart 4. Orexins and Drug Abuse
7. Orexins/hypocretins and addiction
8. Hypocretin 1 receptor regulation of dopaminergic signaling and motivated behavior
9. Orexins and opioid addictionPart 5: Orexins and Cognition
10. Orexins and cognition: neurochemical and anatomical substrates
11. The hypocretin/orexin system and fear learningPart 6: Orexins and Psychological Disorders
12. Orexins and anxiety disorders
13. Orexins as targets for treating brain disorders
Product details
- No. of pages: 188
- Language: English
- Copyright: © Academic Press 2019
- Published: January 3, 2019
- Imprint: Academic Press
- Paperback ISBN: 9780128137512
- eBook ISBN: 9780128137529