The Neuroscience of Normal and Pathological Development

1st Edition - June 5, 2021
Editors: Colin R Martin, Victor R Preedy, Rajkumar Rajendram
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 8 1 8 3 7 1 - 7
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 8 3 7 2 - 4

Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurod… Read more

The Neuroscience of Normal and Pathological Development

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Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. This book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. It also examines pharmacological and non-pharmacological interventions of development-related conditions.

Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with proper and abnormal development. This book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurodevelopment. It also examines in vitro and in vivo modelling of development with stem cells and model systems.

Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience Of Development:

I. Introductory Chapters: Setting The Scene For The Neuroscience Of Development

1. The brain and its structures: an overview
Richard Armstrong

2. Neural tube defects: embryonic origin, clinical features and cell survival equilibrium impact
Valentina Massa and Paolo Grazioli

3. Chemical substances affecting neurodevelopment
Munekazu Komada

4. High-risk babies and Neurodevelopmental outcome
Merina Shrestha

5. Genomic Imprinting and neurodevelopment
S R. Ferron

6. Insights from model systems: Alcohol, neurodevelopment and zebrafish
Robert Gerlai

7. Early life nutrition and brain development: maternal iodine nutrition and neurodevelopment
Shao J. Zhou

8. Endocrine Aspects of Development. Thyroid hormone actions in neurological processes during brain development
Ana Guadaño-Ferraz

II. Impairments and Diseases

9. Pediatric brain tumors
Stephanie Terezakis

10. Neurofibromatosis Type 1: from cellular phenotypes to human brain function
Miguel Castelo-Branco

11. The role and development of neural crest cells
Martin I. Garcia-Castro

12. Spina Bifida: A Biopsychosocial Perspective
Diana Ohanian

13. Diabetic ketoacidosis and neurodevelopment
Aye Tandy

14. Four-dimensional features of fetal brain: applications to diabetes
Panos Antsaklis, George Daskalakis and Asim Kurjak

15. Prenatally exposed to nicotine and neurodevelopment
Kristi A. Kohlmeier

16. Maternal methamphetamine and impact on the brain
Romana Slamberova

17. Alcohol, cannabis and brain development
Kristen Rian Breit

18. The Environmental Pollutant Trichloroethylene Disrupts Key Neural Pathways During Brain Development
Sarah Blossom

19. Developmental neurotoxicity of the herbicide atrazine
Jennifer L. Freeman

20. Neurodevelopmental delays and in utero hyperemesis gravidarum
Marlena Fejzo

21. Neurodevelopment and Infantile Epileptic Encephalopathy-9 (EIEE9)
Maria Passafaro

22. Neurodevelopment in Turner syndrome
Rebecca C. Knickmeyer

23. Very preterm children and the impact on neurodevelopmental outcomes
Peter John Anderson and Leona Pascoe

24. Linking congenital heart disease and brain functional connectivity in newborns
Catherine Limperopoulos and Josepheen De Asis-Cruz

25. Brain Growth in Congenital Heart Disease from Prenatal Environment to Adulthood
Cynthia Ortinau

26. Linking dopamine, amphetamine and neurodevelopment
Cecilia Flores and Lauren Mackenzie Reynolds

27. Developmental coordination disorder
Jill Glennis Zwicker

III. Biomarkers, Screening, Methods and Diagnosis

28. Neurodevelopment and the The Ages and Stages Questionnaire, third edition (ASQ-3)
Nora granana

29. Screening for Attention Deficit Hyperactivity Disorder in children
Steven James Korzeniewski

30. The Mini-Mental State Pediatric Examination screening tool: Italian perspectives
Valeria Peviani

31. Predictors of neurodevelopment in preterm infants: from the neonatal intensive care unit into adulthood
Pilar Medina-Alva

32. The antenatal fetal neurodevelopmental test: uses and applications
T. Hata

IV: Management and Treatments

33. Pain, evaluation and management in neurodevelopmental conditions
Eva Widerstrom-Noga

34. Use of levetiracetam: Features and applications to neonatal seizures
L. Manganas and Shannon Pollock

35. Quetiapine treatment in paediatric scenarios
Maja Drobnic Radobuljac

36. Treatments with cannabinoids and brain development
Fábio Klamt

37. Pediatric dystonia and deep brain stimulation
George Ibrahim

38. Use of repetitive transcranial magnetic stimulation in neurodevelopment: a narrative review
Y. Noda

39. Cognitive behavioral therapy in children with anxiety disorders
Eric A. Storch and Sophie Schneider

40. Cognitive behavioral therapy for anxiety in children with autism spectrum disorder
Eric A. Storch and Sophie Schneider

41. Nutritional treatment in fetal alcohol spectrum disorder
O. Garcia-Algar

42. Nurturing the Developing Brain to Reduce Neurological Delay
Kelly A. Vaughn, Bartlett Moore and Dana DeMaster

43. Normalizing perinatal neurological development via intervention
Dana DeMaster, Kelly A. Vaughn and Bartlett Moore

V. Models And Modelling

44. Microplatforms as a Model for Neurological Conditions
Rami Mhanna

45. Disease models in neurodevelopmental disorders
Maximo Ibo Galindo

46. Endosulfan and impact on neurodevelopment: modelling with zebrafish (Danio rerio)
Ståle Ellingsen

47. Neurodevelopment of the zebrafish spinal serotonin system
Jacob E. Montgomery

48. Inbred mouse model of brain development and intestinal microbiota
Reinaldo B. Oria

49. The myelin mutant taiep rat as a model of developmental disorder
Jose R. Eguibar Sr.

50. The MAM-E17 neurodevelopmental model of schizophrenia
Marzena Mackowiak

VI. Resources

51. Research and recommended resources in the neuroscience of development
Rajkumar Rajendram

　
Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior, and Diet:
I. Genetics, Molecular and Celluar Biology

1. Hereditary motor neuropathies
Carmen Espinos

2. Dopamine transporter (DAT1) polymorphism and development
Karen Elizabeth Waldie

3. Genome wide association studies (GWAS) and neurodevelopment: Autism spectrum disorder
Rita M. Cantor

4. SNPs and cerebral palsy
Juan Antonio Gonzalez-Barrios Sr.

5. Epigenetic regulation of cortical neurogenesis
Mareike Albert

6. Functions and dynamics of axonal mitochondria
G. Gallo

7. Linking apoptosis and caspases in fetal neural tube defects
Aiguo Ren

8. Brain oxidative stress in Down syndrome
Keiichi Ishihara

9. Linking Adhesion GPCRs to Glial Cell Development and Function
X. Piao

10. Immunoglobulin cell adhesion molecule superfamily and neurodevelopment
J. P.H. Burbach

11. Brain-derived neurotrophic factor (BDNF) and neurogenesis
T. Numakawa

12. slc7a5 and neural development
Hiroyuki Sakurai

13. Linking SOX3, SRY and disorders of neurodevelopment
Helena Brentani

14. Neuronal Src-homology-2 (SH2)B adaptor protein-1 (Sh2b1) and brain growth
L. Rui

15. Effects of extrinsic factors and intracellular signalling and transcription factors regulating the development and
cell fate of spinal cord ependymal cells
Masaaki Kitada

16. Signaling molecules controlling oligodendrocyte development and brain myelination
Carmen Sato-Bigbee

II. Neurological and Imaging Features

17. Fetal brain structures: imaging oriented
Elka Miller

18. Four-dimensional (4D) ultrasonography: Methods, uses and fetal neuroscience
Mihaela Grigore

19. Linking histology and neurological development of the fetal and infant brain
Ivica Kostovic and Ana Katušić

20. Development of Corticospinal tract axons: from embryonic stage to adulthood
Hector Ramiro Quinta

21. Vascular endothelial growth factor (VEGF) and neurodevelopment
C. Theiss and V. Theiss

22. Brain-wide connectivity architecture: developmental aspects
Nanyin Zhang

23. Development and pathology of the germinal matrix
Gregory W. Kirschen

24. Development of the GABAergic network in the mouse spinal cord
C. Takayama

25. Postnatal development, electrophysiology and sensory sural nerves
Angel I. Melo

26. Neuroscience of the developing axonal strata in the human fetal brain
Iris Zunic Isasegi

27. Neuroactive steroids and neurodevelopment
Roberto Cosimo Melcangi

28. Voltage and ligand-gated ion channels appearance and function in neurodevelopment
Sahar Kiani and Sara Mirsadeghi

29. Features of brain development over 13 years in preterms
D. Thompson and Courtney Gilchrist

30. The medial pulvinar in neurodevelopment
James Bourne and Jihane Homman-Ludiye

31. Cortical sulci in the human fetal brain and development
Kiho Im

32. The prenatal development of the human cerebellum
J. Dudink

33. Developing cerebello-cerebral connectivity in health and disease: a focus on epilepsy
J. Dudink and Freek Hoebeek

34. Prenatal exposure to progestins: impact on neurodevelopment of the child
Marie-Odile Soyer-Gobillard

III. Physiological Aspects

35. Brain lesion characteristics in relation to upper limb function in children with unilateral cerebral palsy
Lisa Mailleux

36. Maternal exercise and brain development
Cristiane Matte

37. Pyramidal neurons: physiology, Pathophysiology and postnatal development
T.-U. Woo

38. Working memory: physiology and neurodevelopment
Carlos M. Gomez

39. EEG development in resting states
Elena Rodriguez

40. Availability and metabolism of thyroid hormones in the developing brain
Ana Guadaño-Ferraz

IV. Behavior And Psychopathological Aspects

41. Psychosocial issues and quality of life following childhood stroke
Fiadhnait O'Keeffe

42. Neuropsychological function following childhood stroke
Fiadhnait O'Keeffe

43. Youths with autism and working memory
Margot J. Taylor

44. Linking the mesial temporal lobe, 3D probabilistic maps and development
M. Noulhiane

45. Cognitive aspects of Down Syndrome
Claire Enea-Drapeau

46. Adolescent cannabis use and neurocognitive development
Brenden Tervo-Clemmens

47. The Role of Social Anxiety in Autism and the Broader Autism Phenotype: Evidence from Childhood through Adulthood
Cheryl L. Dickter and Josh Burk

48. Impact of touch on bonding and neurodevelopment
I. Croy

49. Neurobehaviour and catch up growth
Akihito Takeuchi

V. Diet And Nutrition

50. Caloric restriction and the developing brain
Cristiane Matte

51. High-fat diet, tryptophan hydroxylase-2 mRNA expression and neurodevelopment
Elinor Sullivan

52. Bone mineral density and nutritional status in children with cerebral palsy
Edgar M. Vasquez-Garibay Sr.

53. Epigallocatechin-3-gallate: linking the neurogenesis, hippocampus and Down syndrome
Renata Bartesaghi

54. Folic acid-to prevent spina bifida and anencephaly
Vijaya Kancherla

Colin R Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.

Affiliations and expertise

Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

Victor R Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Affiliations and expertise

Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UK

Rajkumar Rajendram

Dr Rajkumar Rajendram is a clinician scientist with a focus on internal medicine, anaesthesia, intensive care and peri-operative medicine. He graduated with distinctions from Guy’s, King’s and St. Thomas Medical School, King’s College London in 2001. As an undergraduate he was awarded several prizes, merits and distinctions in pre-clinical and clinical subjects.

Dr Rajendram began his post-graduate medical training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004 and completed specialist training in acute and general medicine in Oxford in 2010. Dr Rajendram subsequently practiced as a Consultant in Acute General Medicine at the John Radcliffe Hospital, Oxford.

Dr Rajendram also trained in anaesthesia and intensive care in London and was awarded a fellowship of the Royal College of Anaesthetists (FRCA) in 2009. He completed advanced training in regional anaesthesia and intensive care. He was awarded a fellowship of the Faculty of Intensive Care Medicine (FFICM) in 2013 and obtained the European diploma of intensive care medicine (EDIC) in 2014. He then moved to the Royal Free London Hospitals as a Consultant in Intensive Care, Anaesthesia and Peri-operative Medicine. He has been a fellow of the Royal College of Physicians of Edinburgh (FRCP Edin) and the Royal College of Physicians of London (FRCP Lond) since 2017 and 2019 respectively. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia.

Dr Rajendram’s focus on improving outcomes from Coronavirus Disease 2019 (COVID-19) has involved research on point of care ultrasound and phenotypes of COVID-19. Dr Rajendram also recognises that nutritional support is a fundamental aspect of medical care. This is particularly important for patients with COVID-19. As a clinician scientist he has therefore devoted significant time and effort into nutritional science research and education. He is an affiliated member of the Nutritional Sciences Research Division of King’s College London and has published over 400 textbook chapters, review articles, peer-reviewed papers and abstracts.

Affiliations and expertise

Consultant in Internal Medicine, King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia