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The Neuroscience of Cocaine - 1st Edition - ISBN: 9780128037508, 9780128037928

The Neuroscience of Cocaine

1st Edition

Mechanisms and Treatment

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Editor: Victor Preedy
Hardcover ISBN: 9780128037508
eBook ISBN: 9780128037928
Imprint: Academic Press
Published Date: 16th May 2017
Page Count: 774
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The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms.

Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse.

Key Features

  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Illustrated in full color
  • Provides unique full coverage of all aspects of cocaine and its related pathology
  • Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms


Researchers and advanced students in neuroscience, pharmacology, psychopathology, and addiction, as well as drug-abuse workers, public-health workers, and physicians treating addiction

Table of Contents

Part 1. Cocaine, Behavior, and Psychopathological Effects
Part 2. Effects of Cocaine Misuse on Neurological Function and Features
Part 3. Pharmacology and Neuropharmacology
Part 4. Withdrawal and Abstinence
Part 5. Cocaine as a Component of Dual-Use and Polydrug Use or Poly Addictions
Part 6. Cellular Effects and Molecular Biology of Cocaine
Part 7. Treatments for Cocaine Misuse and Dependency and Related Features


No. of pages:
© Academic Press 2017
16th May 2017
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK


"...comprehensively covers all aspects of the neurobiology of cocaine and its related pathology. It is an extensive, thorough, in-depth reference regarding all aspects of cocaine's pharmacological, cellular, and molecular effects influencing neurobiological function. Score: 98 - 5 Stars"--Doody's

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