The Nervous System, Discoveries in Pharmacology, Volume 1

The Nervous System, Discoveries in Pharmacology, Volume 1

1st Edition - September 1, 2022

Write a review

  • Editors: Michael Parnham, Clive Page, Jacques Bruinvels
  • Hardcover ISBN: 9780323855198

Purchase options

Purchase options
Available for Pre-Order
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


The Nervous System, Discoveries in Pharmacology, Volume One, the Second Edition in the Discoveries in Pharmacology series, presents commentary from contemporary scholars, an updated bibliography on subjects presented, and contributions from Nobel Prize winners and other pharmacology pioneers. The series brings together acknowledged experts in their fields, providing firsthand accounts of important discoveries and discussing scientific backgrounds and pivotal moments. This volume brings forth discussions on key discoveries in psycho- and neuro-pharmacology, hemodynamics, and hormones, including chapters on antipsychotic agents by Nobel winner Anders Carlsson, Willy Haefely on benzodiazepine, and butyrophenone-type neuroleptics by P. A. J. Janssen and J. P. Tollenaere. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area will find this series a useful teaching tool and launching pad to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. The book will also be of interest to those interested in the history of medicine.

Key Features

  • Contains primary-source documents currently unavailable
  • Presents the science behind major pharmacological breakthroughs by those who discovered them
  • Includes commentary that contextualizes the importance of discoveries and related readings


Academic researchers in pharmacology and medicine as well as advanced students in the area and teachers needing supplementary course material for undergraduate and graduate pharmacology or medical courses

Table of Contents

  • 1. Chemical transmission of nerve impulses
    2. The suppression of psychotic behaviour: Discovery of the clinical use of neuroleptics
    3. The suppression of psychotic behaviour: The discovery of the butyrophenone-type neuroleptics
    4. The suppression of psychotic behaviour: Antipsychotic agents: elucidation of their mode of action
    5. Antidepressants: Clinical discoveries with antidepressant drugs
    6. Antidepressants: Monoamine oxdase and its inhibitors in relation to antidepressive activity
    7. Levodopa and dopamine agonists in the treatment of Parkinson's disease
    8. Alleviation of anxiety
    9. The development of antiepileptic drugs

Product details

  • No. of pages: 510
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: September 1, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323855198

About the Editors

Michael Parnham

Professor Michael J. Parnham, Ph.D., C.Biol.MRSB, FBPhS studied Pharmacology at Chelsea (now King's) College, gaining practical experience in the department of the subsequent Nobel Prize winner, John R. Vane, at the Royal College of Surgeons. With a PhD from Bristol University (1976), he carried out postdoctoral research on prostaglandins and chronic inflammation with Ivan Bonta at Erasmus University Rotterdam, The Netherlands. He established laboratories in pharmacology and toxicology and was Director of Preclinical Discovery working on novel anti-inflammatory macrolides at GSK from 2006. From 2012 to 2019, Prof. Parnham built up preclinical research in the Fraunhofer Institute of Molecular Biology & Applied Ecology IME. Dr. Parnham has published and lectured extensively and organised symposia on various aspects of immunopharmacology and anti-inflammatory therapy and in 2015, received a Lifetime Achievement Award from the International Association of Inflammatory Societies (IAIS). He is a scientific advisor to several companies.

Affiliations and Expertise

Professor, Faculty of Biochemistry, Chemistry and Pharmacy, Goethe University Frankfurt, Frankfurt am Main, Germany

Clive Page

Professor Clive P. Page, BSc PhD OBE HonFBPhS is a Professor of Pharmacology, King’s College London and Director of the Sackler Institute of Pulmonary Pharmacology, King’s College London. Clive’s main research interests are in the pharmacology of inflammation and respiratory disease and he has published over 250 scientific papers. Clive was the co-founder and previous Chairman of the Board of Verona Pharma plc, an AIM listed Company developing new drugs for the treatment of Respiratory Diseases. He is a Non Executive Director of and on boards of several companies. He was awarded the Society of Biology President’s Medal in 2012 for an outstanding contribution to the life sciences over the previous year. He is a Fellow of the Royal Society of Biology and an Honorary Fellow and President Elect of the British Pharmacological Society. In 2017, Clive was awarded an OBE for Services to Pharmacology.

Affiliations and Expertise

Professor of Pharmacology and Director, Sackler Institute of Pulmonary Pharmacology, King’s College London, UK

Jacques Bruinvels

Professor Jacques Bruinvels, Ph.D. is Professor Emeritus of Pharmacology, Department of Pharmacology, Erasmus University Rotterdam, Rotterdam, The Netherlands. Full biography to follow

Affiliations and Expertise

Professor Emeritus of Pharmacology, Department of Pharmacology, Erasmus University Rotterdam, Rotterdam, The Netherlands

Ratings and Reviews

Write a review

There are currently no reviews for "The Nervous System, Discoveries in Pharmacology, Volume 1"