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Volume IV Immunology
The Molecular Basis of Lymphoid Architecture in the Mouse Carola G. Vinuesa and Matthew C. Cook
The Biology of Toll-like Receptors in Mice Osamu Takeuchi and Shizuo Akira
Genomic Organization of the Mouse Major Histocompatibility Complex Attila Kumánovics
Some Biological Features of Dendritic Cells in the Mouse Kang Liu, Anna Charalambous and Ralph M. Steinman
Mouse Models Revealed the Mechanisms for Somatic Hypermutation and Class Switch
Recombination of Immunoglobulin Genes Maria D. Iglesias-Ussel, Ziqiang Li, and Matthew D. Scharff
Mouse Natural Killer Cells: Function and Activation Francesco Colucci
Cytokine-activated JAK-STAT Signaling in the Mouse Immune System Bin Liu and Ke Shuai
Signal Transduction Events Regulating Integrin Function and T Cell Migration in the Mouse Lakshmi R. Nagarajan and Yoji Shimizu
Mouse Models of Negative Selection Troy A. Baldwin, Timothy K. Starr and Kristin A. Hogquist
Peripheral Tolerance of T Cells in the Mouse Vigo Heissmeyer, Bogdan Tanasa, and Anjana Rao
The Genetics of Mouse Models of Systemic Lupus Srividya Subramanian and Edward K. Wakeland
Inhibitory Receptors and Autoimmunity in the Mouse Menna R. Clatworthy and Kenneth G.C. Smith
Mouse Models of Immunodeficiency B. Anne Croy, James P. Di Santo, Marcus Manz, and Richard B. Bankert
Mouse Models to Study the Pathogenesis of Allergic Asthma Chad E. Green, Nicholas J. Kenyon, Scott I. Simon, and Fu-Tong Liu
The Mouse Trap: How Well Do Mice Model Human Immunology? Javier Mestas and Christopher C.W. Hughes
Immunology, the third volume in the four volume set, The Mouse in Biomedical Research, is a completely new addition to this series, dedicated to mouse immunology. It is based on the vast body of knowledge which has made the mouse the model of choice when studying immunity in man. Arguably more is known about the immune system in mice than any other species except man. In large part this is due to the power of genetic engineering to delineate molecular mechanisms. In this volume we present an Overview to mouse immunology, including both the innate and adaptive immune systems, followed by 15 chapters, each dealing with a specific area of immunology in the mouse. These chapters illustrate the power of genetic engineering in dissecting each component of the immune response from the development of lymphoid tissues to signal transduction pathways in activated cells.
Veterinary and medical students, graduate students, post-docs, immunologists, and researchers who utilize animals in biomedical research
- No. of pages:
- © Academic Press 2006
- 5th December 2006
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.
Massachusetts Institute of Technology, Cambridge, MA, USA
Center for Comparative Medicine, UC Davis School of Veterinary Medicine, Davis CA
The Jackson Laboratory, Bar Harbor, Maine
Research Animal Resources and Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD
Laboratory Animal Research Center, The Rockefeller University, New York, NY
School of Veterinary Medicine, University of Pennsylvania Philadelphia, PA
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