The Mouse in Biomedical Research - 2nd Edition - ISBN: 9780123694553, 9780080469065

The Mouse in Biomedical Research, Volume 1

2nd Edition

History, Wild Mice, and Genetics

Serial Volume Editors: James Fox Stephen Barthold Muriel Davisson Christian Newcomer Fred Quimby Abigail Smith
eBook ISBN: 9780080469065
Hardcover ISBN: 9780123694553
Imprint: Academic Press
Published Date: 4th December 2006
Page Count: 352
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Table of Contents

Volume I History, Genetics, and Wild Mice

  1. Building a Better Mouse: One Hundred Years of Genetics and Biology Herbert C. Morse III

  2. Systematics of the genus Mus Priscilla K. Tucker

  3. The Secret World of Wild Mice Grant R. Singleton and Charles J. Krebs

  4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types Melissa L. Berry and Carol Cutler Linder

  5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide Janan T. Eppig

  6. The Mouse Genome Mark D. Adams

  7. Gene Mapping Muriel T. Davisson

  8. Genetic Monitoring Richard R. Fox, Michael V. Wiles, and Petko M. Petkov

  9. Cytogenetics Muriel T. Davisson and Mary Ann Handel

  10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man M.H. Kaufman

  11. Gamete and Embryo Manipulation K.C. Kent Lloyd

  12. Chemical Mutagenesis in Mice Martin Hrabé de Angelis, Dian Michel, Sibylle Wagner, Sonja Becker and Johannes Beckers

  13. Gene-Specific Mutagenesis
    K.C. Kent Lloyd

  14. Gene Transfer Studies Using Mouse Models Robert G. Pergolizzi and Ronald G. Crystal

  15. Mouse and Human Pluripotent Stem Cells Leslie F. Lock

  16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics Lucia F. Jorge-Nebert, Sandrine Derkenne and Daniel W. Nebert


History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.


Researchers in laboratory medicine, genetics, immunology, infectious diseases and lab animals


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© Academic Press 2007
Academic Press
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Ratings and Reviews

About the Serial Volume Editors

James Fox Serial Volume Editor

Affiliations and Expertise

Massachusetts Institute of Technology, Cambridge, MA, USA

Stephen Barthold Serial Volume Editor

Affiliations and Expertise

Center for Comparative Medicine, UC Davis School of Veterinary Medicine, Davis CA

Muriel Davisson Serial Volume Editor

Affiliations and Expertise

The Jackson Laboratory, Bar Harbor, Maine

Christian Newcomer Serial Volume Editor

Affiliations and Expertise

Research Animal Resources and Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD

Fred Quimby Serial Volume Editor

Affiliations and Expertise

Laboratory Animal Research Center, The Rockefeller University, New York, NY

Abigail Smith Serial Volume Editor

Affiliations and Expertise

School of Veterinary Medicine, University of Pennsylvania Philadelphia, PA