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Volume I History, Genetics, and Wild Mice
1. Building a Better Mouse: One Hundred Years of Genetics and Biology
Herbert C. Morse III
2. Systematics of the genus Mus
Priscilla K. Tucker
3. The Secret World of Wild Mice
Grant R. Singleton and Charles J. Krebs
4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
Melissa L. Berry and Carol Cutler Linder
5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
Janan T. Eppig
6. The Mouse Genome
Mark D. Adams
7. Gene Mapping
Muriel T. Davisson
8. Genetic Monitoring
Richard R. Fox, Michael V. Wiles, and Petko M. Petkov
Muriel T. Davisson and Mary Ann Handel
10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man
11. Gamete and Embryo Manipulation
K.C. Kent Lloyd
12. Chemical Mutagenesis in Mice
Martin Hrabé de Angelis, Dian Michel, Sibylle Wagner, Sonja Becker and Johannes Beckers
13. Gene-Specific Mutagenesis
K.C. Kent Lloyd
14. Gene Transfer Studies Using Mouse Models
Robert G. Pergolizzi and Ronald G. Crystal
15. Mouse and Human Pluripotent Stem Cells
Leslie F. Lock
16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics
Lucia F. Jorge-Nebert, Sandrine Derkenne and Daniel W. Nebert
History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.
Researchers in laboratory medicine, genetics, immunology, infectious diseases and lab animals
- No. of pages:
- © Academic Press 2006
- 4th December 2006
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.
Massachusetts Institute of Technology, Cambridge, MA, USA
Center for Comparative Medicine, UC Davis School of Veterinary Medicine, Davis CA
The Jackson Laboratory, Bar Harbor, Maine
Research Animal Resources and Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD
Laboratory Animal Research Center, The Rockefeller University, New York, NY
School of Veterinary Medicine, University of Pennsylvania Philadelphia, PA
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