
The Mouse in Biomedical Research, Volume 1
2nd Edition
History, Wild Mice, and Genetics
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Table of Contents
Volume I History, Genetics, and Wild Mice
Building a Better Mouse: One Hundred Years of Genetics and Biology Herbert C. Morse III
Systematics of the genus Mus Priscilla K. Tucker
The Secret World of Wild Mice Grant R. Singleton and Charles J. Krebs
Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types Melissa L. Berry and Carol Cutler Linder
Mouse Strain and Genetic Nomenclature: an Abbreviated Guide Janan T. Eppig
The Mouse Genome Mark D. Adams
Gene Mapping Muriel T. Davisson
Genetic Monitoring Richard R. Fox, Michael V. Wiles, and Petko M. Petkov
Cytogenetics Muriel T. Davisson and Mary Ann Handel
Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man M.H. Kaufman
Gamete and Embryo Manipulation K.C. Kent Lloyd
Chemical Mutagenesis in Mice Martin Hrabé de Angelis, Dian Michel, Sibylle Wagner, Sonja Becker and Johannes Beckers
Gene-Specific Mutagenesis
K.C. Kent LloydGene Transfer Studies Using Mouse Models Robert G. Pergolizzi and Ronald G. Crystal
Mouse and Human Pluripotent Stem Cells Leslie F. Lock
Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics Lucia F. Jorge-Nebert, Sandrine Derkenne and Daniel W. Nebert
Description
History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.
Readership
Researchers in laboratory medicine, genetics, immunology, infectious diseases and lab animals
Details
- No. of pages:
- 352
- Language:
- English
- Copyright:
- © Academic Press 2007
- Published:
- 4th December 2006
- Imprint:
- Academic Press
- Hardcover ISBN:
- 9780123694553
- eBook ISBN:
- 9780080469065
Ratings and Reviews
About the Serial Volume Editors
James Fox
James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.
Affiliations and Expertise
Massachusetts Institute of Technology, Cambridge, MA, USA
Stephen Barthold
Affiliations and Expertise
Center for Comparative Medicine, UC Davis School of Veterinary Medicine, Davis CA
Muriel Davisson
Affiliations and Expertise
The Jackson Laboratory, Bar Harbor, Maine
Christian Newcomer
Affiliations and Expertise
Research Animal Resources and Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD
Fred Quimby
Affiliations and Expertise
Laboratory Animal Research Center, The Rockefeller University, New York, NY
Abigail Smith
Affiliations and Expertise
School of Veterinary Medicine, University of Pennsylvania Philadelphia, PA
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