The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in
The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
List of Contributors Preface Part I: Virulent Bacteriophages Chairman's Remarks The Natural History of Viruses as Suggested by the Structure of Their DNA Molecules Control of Virus: Induced Enzyme Synthesis in Bacteria Polypeptides Associated with Morphogenic Defects in Bacteriophage The Control of Protein Synthesis after Phage Infection Part II: Temperate Bacteriophages The Position and Orientation of Genes in λ and λ dg DNA The Synthesis of the λ Chromosome: The Role of the Prophage Termini The Regulation of Viral Genes and the Uncontrolled Expression of the Galactose Genes during λ Development Regulation and Development of the Temperate Phage Lambda Specificity of in Vitro RNA Synthesis on Lambda DNA Templates Part III: Single-Stranded DNA Bacteriophages Bacteriophage øX174: Viral Functions Gene Function in Phage S13 Heterozygotes of Phage fl Conditional Lethal Mutants of Coliphage M13 Discussion—Part III Part IV: RNA Bacteriophages Structure and Function of RNA from Small Phages The Interaction of Male-Specific Bacteriophage with F Pili Viral "Minus" Strands and the Replication of RNA Phages Infectious M12 Phage Replication Form RNA: A Tool for Studying Viral RNA Replication RNA Phage-Specific RNA Synthesis in Escherichia coli Discussion—Part IV Part V: Mammalian RNA Viruses Biological and Physicochemical Aspects of Poliovirus-Induced Double-Stranded RNA The Synthesis and Translation of Poliovirus RNA Genetics and Biochemistry of Arbovirus Temperature-Sensitive Mutants Studies on the Replication of Reovirus Inhibitory Effect of a Cytidine Analog on the Growth of Rabies Virus: Comparative Studies with Other Metabolic Inhibitors Properties of RNA from Vesicular Stomatitis Virus Discussion—Part V Part VI: Mammalian DNA Viruses Early and Late Functions during the Vaccinia Virus Multiplica
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- © Academic Press 1967
- 1st January 1967
- Academic Press
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