The Molecular Biology of Viruses

The Molecular Biology of Viruses

Colter and Paranchych

1st Edition - January 1, 1967

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  • Editor: John Colter
  • eBook ISBN: 9780323142731

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The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.

Table of Contents

  • List of Contributors


    Part I: Virulent Bacteriophages Chairman's Remarks

    The Natural History of Viruses as Suggested by the Structure of Their DNA Molecules

    Control of Virus: Induced Enzyme Synthesis in Bacteria

    Polypeptides Associated with Morphogenic Defects in Bacteriophage

    The Control of Protein Synthesis after Phage Infection

    Part II: Temperate Bacteriophages

    The Position and Orientation of Genes in λ and λ dg DNA

    The Synthesis of the λ Chromosome: The Role of the Prophage Termini

    The Regulation of Viral Genes and the Uncontrolled Expression of the Galactose Genes during λ Development

    Regulation and Development of the Temperate Phage Lambda

    Specificity of in Vitro RNA Synthesis on Lambda DNA Templates

    Part III: Single-Stranded DNA Bacteriophages

    Bacteriophage øX174: Viral Functions

    Gene Function in Phage S13

    Heterozygotes of Phage fl

    Conditional Lethal Mutants of Coliphage M13

    Discussion—Part III

    Part IV: RNA Bacteriophages

    Structure and Function of RNA from Small Phages

    The Interaction of Male-Specific Bacteriophage with F Pili

    Viral "Minus" Strands and the Replication of RNA Phages

    Infectious M12 Phage Replication Form RNA: A Tool for Studying Viral RNA Replication

    RNA Phage-Specific RNA Synthesis in Escherichia coli

    Discussion—Part IV

    Part V: Mammalian RNA Viruses

    Biological and Physicochemical Aspects of Poliovirus-Induced

    Double-Stranded RNA

    The Synthesis and Translation of Poliovirus RNA

    Genetics and Biochemistry of Arbovirus Temperature-Sensitive Mutants

    Studies on the Replication of Reovirus

    Inhibitory Effect of a Cytidine Analog on the Growth of Rabies Virus: Comparative Studies with Other Metabolic Inhibitors

    Properties of RNA from Vesicular Stomatitis Virus

    Discussion—Part V

    Part VI: Mammalian DNA Viruses

    Early and Late Functions during the Vaccinia Virus Multiplication Cycle

    Enzyme Inductions in Cell Cultures during Productive and Abortive

    Infections by Papovavirus SV40

    Studies on the Control of the Infective Process in Cells Infected with Pseudorabies Virus

    Control of Biosynthesis of Host Macromolecules in Cells Infected with Adenoviruses

    Discussion—Part VI

    Part VII: Oncogenic Viruses I

    Studies on the Basis for the Observed Homology between DNA from Polyoma Virus and DNA from Normal Mouse Cells

    On the Interaction of Polyoma Virus with the Genetic Apparatus of Host Cells

    Deoxyribonucleic Acid Synthesis in Cells Infected with Polyoma Virus

    Analysis of Some Viral Functions Related to Neoplastic Transformation

    Discussion—Part VII

    Part VIII: Oncogenic Viruses II

    On the Mechanism of Transformation of Mammalian Cells by SV40

    Tumor Virus RNA and the Problem of Its Synthesis

    Metabolic Requirements in Rous Sarcoma Virus Replication

    Studies on Carcinogenesis by Avian Sarcoma Viruses

    Discussion—Part VIII

    Subject Index

Product details

  • No. of pages: 746
  • Language: English
  • Copyright: © Academic Press 1967
  • Published: January 1, 1967
  • Imprint: Academic Press
  • eBook ISBN: 9780323142731

About the Editor

John Colter

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