Key Features

  • Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer.
  • Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures.
  • Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy.

Table of Contents

The Molecular Basis of Cancer, 4e

Mendelsohn, Howley, Israel, Gray, Thompson

 

Part I: Carcinogenesis and Cancer Genetics

1. Cancer, A Genetic Disorder

2. Oncogenes and Signal Transduction

3. Tumor Suppressor Genes

4. Genomic Instability and DNA Repair

5. Epigenetics and Cancer

6. Infectious Agents and Cancer

7. Environmental Carcinogenesis

8. Animal Models: Flies, Fish and Yeast

9. Genetic Mouse Models of Cancer

Part II: Cancer Biology

10. Cancer Stem Cells

11. Regulation of the Cell Cycle

12. Cell Growth

13. Cancer Cell Metabolism

14. Apoptosis, Autophagy and Necrosis

15. Cell Growth Arrest and Senescence

  16. Stromal-Cancer Interactions in the Microenvironment

  17. Hypoxia and Angiogenesis

18. Invasion and Metastasis

19. Inflammation and Cancer

  20. Molecular Pathways and Systems Biology

Part III: Molecular Pathology and Diagnostics

21. Biomarkers Assessing Risk of Cancer

22. Biomarkers for Detecting Cancer: Molecular Screening

  23. Biomarkers for Predicting Response to Specific Therapy

24. The Technology of Analyzing Nucleic Acids

25. Imaging Cancer

  

Details

No. of pages:
888
Language:
English
Copyright:
© 2015
Published:
Imprint:
Saunders
Print ISBN:
9781455740666
Electronic ISBN:
9780323324885