Section I. The mitochondrion and gametes
Chapter 1 The role of the mitochondrion in sperm function. Is there a place for oxidative phosphorylation or is this a purely glycolytic process? Eduardo Ruiz-Pesini, Carmen Díez-Sánchez, Manuel José López-Pérez and José Antonio Enríquez
Chapter 2 The role of mitochondrial function in the oocyte and embryo Remi Dumollard, Michael Duchen, John Carroll
Chapter 3 Mitochondrial DNA in the Oocyte and the developing embryo Pascale May-Panloup, Marie-Françoise Chretien, Yves Malthier, Pascal Reynier
Section II. Transmission
Chapter 4 Mitochondrial DNA and the mammalian oocyte Eric A. Shoubridge and Timothy Wai
Chapter 5 Mitochondrial disease - its impact, aetiology and pathology McFarland R, Taylor RW and Turnbull DM
Chapter 6 Cybrid models of mtDNA disease and transmission, from cells to mice Ian A. Trounce, Carl A. Pinkert
Section III. The use of ARTs to regulate mtDNA disease.
Chapter 7 The use of Micromanipulation Methods as a Tool to Prevention of Transmission of Mutated Mitochondrial DNA Helena Fulka, Josef Fulka, Jr.
Chapter 8 Difficulties and possible solutions in the Genetic Management of mtDNA disease in the pre-implantation embryo Joanna Poulton, Pippa Oakeshott, Stephen H. Kennedy
Section IV. The effects of invasive ARTs on mtDNA transmission
Impact of assisted reproductive techniques: a mitochondrial perspective from the cytoplasmic transplantion
Carol Brenner, A. J. Harvey, T. C. Gibson
Chapter 10 Nuclear Transfer – preservation of a nuclear genome at the expense of its associated mtDNA genome(s) Emma J. Bowles, Keith H. S. Campbell, Justin C. St. John
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. These volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
- Includes many descriptive figures
- Topics covered include the role of mitochondrial function, the use of ARTs to regulate mtDNA disease, nuclear transfer, and more
- Latest volume in the series that covers 10 reviews from leading authorities in developmental biology
Developmental biologists, cell biologists, genetics researchers, molecular biologists, and plant and animal biologists
- No. of pages:
- © Academic Press 2007
- 17th January 2007
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
University of Pittsburgh School of Medicine, PA, U.S.A.
The Medical School, The University of Birmingham, U.K.