The Management of Scientific Integrity within Academic Medical Centers

The Management of Scientific Integrity within Academic Medical Centers discusses the impact scientific misconduct has in eight complex case studies. Authors look at multifaceted mixtures of improper behavior, poor communication, cultural issues, adverse medical/health issues, interpersonal problems and misunderstandings to illustrate the challenge of identifying and managing what went wrong and how current policies have led to the establishment of quasi legal processes within academic institutions. The book reviews the current global regulations and concludes with a section authored by a US federal court judge who provides his perspective on the adequacy of current regulations and policies.

• Shows how complex most scientific integrity cases are, and how little is clear cut in the adjunction of each
• Discusses how timely and important scientific misconduct is, and its impact on science at large
• Reviews the current regulations and policies that guide how we manage scientific integrity
• Examines this complexity in 8 anonymous case studies
• Concludes with a section authored by an expertly qualified federal court judge

Students/researchers interested in science and ethics, graduate students in public policy and in the biomedical sciences (across disciplines), faculty at academic medical centers, and those engaged in healthcare administration who must manage the oversight of scientific integrity. Psychologists and trainees as well.

• Dedications
• Foreword
• About the Authors
• Acknowledgments
• Chapter 1. Introduction: Research Misconduct in Biomedical Research Institutions
• Chapter 2. Research Integrity: The Legal and Regulatory Landscape
  • 1. Introduction
  • 2. The Institutional and Agency Process
  • 3. Other Legal Consequences for Researchers Engaging in Research Misconduct
  • 4. Process-Based Challenges
  • 5. Other Types of Claims Arising Out of Institutional Proceedings
  • 6. Litigation over Records
  • 7. Summary
• Case Studies
  • Introduction
    • A Note on the Presentation of Nine Research Integrity Case Studies
  • Chapter 3. Question of Data Manipulation in Failure to Replicate Findings in Published Manuscript
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 4. Violation of Institutional and Public Health Service Policies Governing the Care and Use of Animals in Research: Cultural Barriers in the Academic Workplace
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 5. Research Assistants Coming Forward with Concerns about Perceived Behavior of Principal Investigator
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 6. Questionable Mentorship and Oversight of Federal Grant Funding
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions For Discussion
  • Chapter 7. Submission of Fraudulent Data to a Peer-Review Journal: What Is the Role of the Lab Head/Mentor?
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Interview with Dr Alatas
    • 6. Interview with Dr Perkasa
    • 7. Synthesis and Formulation
    • 8. Resolution
    • 9. Commentary
    • Questions for Discussion
  • Chapter 8. Plagiarism versus Data Shared between Junior and Senior Investigators
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 9. Misappropriation and Use of Data from a Multisite and Multi-investigator Study
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 10. Determining the Extent of Data Fabrication Following an Apparent Single Incident
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 11. Anonymous Allegations of Scientific Misconduct
    • 1. Presenting Complaint
    • 2. Background and History
    • 3. Relevant Evidence
    • 4. Case Management and Adjudication
    • 5. Synthesis and Formulation
    • 6. Resolution
    • 7. Commentary
    • Questions for Discussion
  • Chapter 12. Management of Research Integrity within Academic Medical Centers: A Summary and Suggested “Best Practices”
    • 1. Themes Illustrated in the Case Material
    • 2. Recommendations and Best Practices
    • 3. Conclusion
• Appendix 1. Federal Policy on Research Misconduct
• Appendix 2. Lifespan System-wide Policy
• Appendix 3. Policies and Procedures for Dealing with Allegations of Academic Misconduct at Yale University
• Index