The Liver

The Liver

Oxidative Stress and Dietary Antioxidants

1st Edition - January 3, 2018

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  • Editors: Vinood Patel, Rajkumar Rajendram
  • Paperback ISBN: 9780128039519
  • eBook ISBN: 9780128039786

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Description

The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies.

Key Features

  • Provides a framework for in-depth analysis of the basic processes of oxidative stress, from molecular biology, to whole organs in relation to the liver
  • Bridges the trans-disciplinary divide between the basic science and mechanisms of liver disease and oxidative stress to advance medical sciences and enable preventative and treatment strategies
  • Contains contributions from leading national and international experts, including those from world renowned institutions

Readership

Research scientists, gastroenterologists, nutritionists and physicians

Table of Contents

  • Oxidative Stress and the Liver
    1. Oxidative stress in hepatitis C infection 
    Birke Bartosch
    2. Peroxidases and oxidative stress in fatty livers 
    Lixin Zhu
    3. Alterations in nucleocytoplasmic localization of the methionine cycle induced by oxidative stress during liver disease  
    Maria Angeles Pajares
    4. Oxidative stress in iron toxicity of the liver
    Kosha Mehta
    5. Cardiac glycosides and oxidative stress in liver cancer
    Rengul Cetin-Atalay
    6. Acetaldehyde effects on cellular redox state. 
    Luis Enrique Gomez-Quiroz
    7. The role of glyoxalase-I in oxidant stress of liver damage
    Marcus Hollenbach
    8. Antioxidants 1 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury an overview
    Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger

    Antioxidants and the Liver
    9. Antioxidants 2 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury: role of arginine and glutamine 
    Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger
    10. Antioxidants 2 Reactive oxygen and nitrogen species and liver ischemia-reperfusion injury: role of lipoic acid
    Fabienne T.E. Alban, Rowan F. van Golen, Daniel Gyamfi and Michal Heger
    11. Oxidative stress as crucial factor in liver disease: Potential Therapeutic effect of Antioxidants 
    H.A. Hassan
    12. L-NAME as a synthetic antioxidant in liver injury 
    Adnan Ayhanci, Sila Appak and Mustafa Cengiz
    13. Vitamin C, oxidative stress and liver protection 
    Rocio IR Macias
    14. Lycopene, liver protection and oxidative stress 
    Kazim Sahin
    15. Vitamin E protection against hyperthyroidism-induced liver oxidative stress
    Paola Venditti
    16. Citric acid an antioxidant in liver  
    O. M. E. Abdel-salam
    17. Resveratrol and protection in hepatic steatosis: antioxidant effects 
    Maria Puy Portillo
    18. Astaxanthin, a marine carotenoid against hepatic oxidative stress: A systematic review. 
    C.V. Anuradha
    19. Effects of melatonin as an antioxidant in liver 
    Vijay K. Bharti
    20. Antioxidant role of the Mayan fruit canistel (Pouteria campechiana) in liver protection
    T. Sivasudha
    21. Endogenous mitochondrial aldehyde dehydrogenase-2 as an antioxidant in liver
    Yanfeng Wang
    22. Comparing antioxidants in liver disease: L-carnitine, N-acetylcysteine and genistein 
    Kaan Demiroren
    23. Coenzyme Q10, liver protection and oxidative stress 
    Farnaz Farsi, Pezhman Alavinejad Sr. and Nava Morshedzadeh
    24. Carnosine as a putative antioxidant in usage against liver disease
    S. Dogru-Abbasoglu
    25. Dioscin as a natural saponin and protection in oxidative stress in hepatic fibrosis
    J. Peng
    26. Gallic acid as a putative antioxidant in usage against liver disease
    Jesus Morlett-Chavez
    27. Oleuropein as an antioxidant and liver protection
    Seung Kew Yoon
    28. Garlic and Liver Diseases 
    George L. Tipoe, Jia Xiao, Liangliang Zou, Rui Zhang and Hao Gao

Product details

  • No. of pages: 368
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: January 3, 2018
  • Imprint: Academic Press
  • Paperback ISBN: 9780128039519
  • eBook ISBN: 9780128039786

About the Editors

Vinood Patel

Dr Vinood B. Patel is a Senior Lecturer in Clinical Biochemistry at the University of Westminster and honorary fellow at King’s College London. He presently directs studies on metabolic pathways involved in liver disease, particularly related to mitochondrial energy regulation and cell death.

Affiliations and Expertise

Professor, University Westminster, UK

Rajkumar Rajendram

Dr. Rajendram is a clinician scientist whose focus is on perioperative medicine, anesthesia, and intensive care. He graduated in 2001 with a distinction from Guy’s, King’s, and St. Thomas Medical School in London, and began his postgraduate medical training in general medicine and intensive care in Oxford. Dr. Rajendram returned to Oxford as a consultant in general medicine at the John Radcliffe Hospital, Oxford, before moving to the Royal Free London Hospitals as a consultant in intensive care, anesthesia, and perioperative medicine. He is currently a consultant in internal and perioperative medicine at King Abdulaziz Medical City, Riyadh, Saudi Arabia. As a visiting lecturer in the Division of Diabetes and Nutritional Sciences, King’s College London, he has published over 100 textbook chapters, review articles, peer-reviewed papers, and abstracts.

Affiliations and Expertise

Visiting Lecturer, Division of Diabetes and Nutritional Sciences, King’s College London, UK

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