The Inflammatory Process - 2nd Edition - ISBN: 9780127834023, 9781483220802

The Inflammatory Process

2nd Edition

Volume 2

Editors: Benjamin W. Zweifach Lester Grant Robert T. McCluskey
eBook ISBN: 9781483220802
Imprint: Academic Press
Published Date: 1st January 1973
Page Count: 436
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.


The Inflammatory Process, Second Edition is an account of the inflammatory process and covers topics ranging from microvascular aspects of tissue injury and capillary permeability to rheologic factors in inflammation. The effects of inflammation on the lymphatic system are also explored, along with the sticking and emigration of white blood cells in inflammation.

Comprised of 11 chapters, this volume begins with an overview of vascular events in the inflammatory process, paying particular attention to the microvascular aspects of tissue injury and structural and physiological considerations in capillary permeability. The rheology of inflammation and the effects of inflammation on the lymphatic system are also examined. Subsequent chapters focus on the natural role of amines, polypeptides, and proteases in the inflammatory process; mediation of increased vascular permeability in inflammation; and hemostatic mechanisms in tissue injury. The book concludes with an analysis of thrombosis as an initiator of inflammation and as a complication of inflammation, and how it can be prevented.

This monograph will be of interest to practitioners in fields ranging from biochemistry to pathology, bacteriology, physiology, and immunology.

Table of Contents

List Of Contributors


Preface to First Edition

Contents of Other Volumes

Part I. Vascular Events in the Inflammatory Process

Chapter 1. Microvascular Aspects of Tissue Injury

I. General Aspects of Reaction

II. Specific Components

III. Summary


Chapter 2. Capillary Permeability

I. Structural Consideration

I. Introduction

II. Permeability of Capillaries

III. Capillary Structure

IV. Discussion of Various Mechanisms Proposed for the Control of Capillary Permeability

V. Summary and Conclusions


Chapter 3. Capillary Permeability

II. Physiological Considerations

I. Introduction

II. General Outline of Capillary Permeability

III. Modes of Transport through Capillary Walls

IV. Methods for Studying Diffusion Permeability of Capillaries


Chapter 4. Capillary Permeability

III. Connective Tissue

I. Historical Perspective

II. Morphology and Composition of Connective Tissue

III. Organization and Functions of Connective Tissue

IV. Physical Chemistry of Connective Tissue

V. Role of the Connective Tissue in Vascular Exchange

VI. Reaction of Connective Tissue of Certain Agents

VII. Connective Tissue Homeostasis


Chapter 5. Rheologic Factors in Inflammation

I. Introduction

II. Rheology of Normal Blood

III. Rheology of Inflammation

IV. Summary


Chapter 6. The Lymphatic System in Inflammation

I. Introduction

II. Structure

III. Permeable Paths through the Lymphatic Wall

IV. Functioning of the Lymphatic System

V. Effects of Inflammation on the Lymphatic System

VI. Effects of the Lymphatic System on Inflammation

VII. Therapeutic Measures


Chapter 7. The Sticking and Emigration of White Blood Cells in Inflammation

I. Introduction

II. History of the Problem

III. Fate of Emigrated Cells in the Extravascular Tissue

IV. The Influence of pH on the Emigration of White Cells

V. Relationship Between White Cell Sticking and Vascular Permeability

VI. Chemotaxis

VII. Electrochemical Factors

VIII. Summary


Chapter 8. Chemical Mediators

I. Introduction

II. Early Vascular Events in Inflammation

III. Endogenous Mediators of the Vascular Events

IV. Evidence for the Natural Role of Amines, Polypeptides, and Proteases in the Inflammatory Process

V. Inflammatory Response in Various Organs

VI. Conclusions


Chapter 9. Mediation of Increased Vascular Permeability in Inflammation

I. Introduction

II. Acute Inflammation

III. Trigger Mechanisms

IV. Leukocytes as Mediators

V. The Case against Mediators

VI. Delayed Hypersensitivity

VII. Unifying Hypothesis of Inflammation

VIII. Conclusions

Note Added in Proof


Part II. Hematological Considerations

Chapter 10. Hemostatic Mechanisms in Tissue Injury

I. Introduction

II. The Hemostatic Plug

III. Vascular and Tissue Factors in Hemostasis

IV. Hemostasis as a Whole


Chapter 11. Thrombosis

I. Thrombosis as an Initiator of Inflammation

II. Thrombosis as a Complication of Inflammation

III. Prevention of Thrombosis


Author Index

Subject Index


No. of pages:
© Academic Press 1973
Academic Press
eBook ISBN:

About the Editor

Benjamin W. Zweifach

Lester Grant

Robert T. McCluskey

Ratings and Reviews