The Human Genome - 2nd Edition - ISBN: 9780123334626, 9780080474588

The Human Genome

2nd Edition

A User's Guide

Authors: Julia Richards R. Scott Hawley
eBook ISBN: 9780080474588
Imprint: Academic Press
Published Date: 7th October 2004
Page Count: 480
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Description

This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society.

The Human Genome, Second Edition is ideal for students and non-professionals, but will also serve as a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics.

Key Features

New in this edition: · 60% new material, including data from the Human Genome Project and the latest genetics and ethics discussions · Several new case studies and personal stories that bring the concepts of genetics and heredity to life · Simplified treatment of material for non-biology majors · New full-color art throughout the text · New co-author, Julia Richards, joins R. Scott Hawley in this revision

Readership

Professionals and educated laypersons studying the impact of genetics, medicine, and society; and non-biology majors in courses such as Genetics in Society.

Table of Contents

Acknowledgments Preface

SECTION 1: The Basics of Heredity

  1. Slaying Molecular Dragons: Brenda’s Tale
  2. The Answer in a Nutshell: Genes, Proteins, and the Basis of Life
  3. Mendel and the Concept of the Gene
  4. Human Mendelian Genetics
  5. One Man’s Trait Is Another Man’s DiseaseSECTION 2: The Central Dogma of Molecular Biology
  6. DNA: The Genetic Alphabet
  7. The Central Dogma of Molecular Biology: How Genes Encode Proteins
  8. Splicing the Modular Gene
  9. Orchestrating the Human GenomeSECTION 3: How Chromosomes Move
  10. So What are Chromosomes Anyway?
  11. How Cells Move Your Genes Around
  12. Passing Genes Between Generations
  13. The Chromosomal Basis of HereditySECTION 4: Mutation
  14. Absent Essentials and Monkey Wrenches
  15. How We Detect Mutations
  16. We Are All Mutants
  17. What Constitutes Normal?
  18. Mutations in Mammoth Genes
  19. Expanded Repeat TraitsSECTION 5: Genes, Chromosomes, and Sex
  20. The X and Y Chromosomes: The Odd Couple
  21. Genetics of Sex, Gender, and Orientation
  22. Aneuploidy: When Too Much or Too Little CountsSECTION 6: Breaking the Rules
  23. Imprinting
  24. Imitating Heredity: One Trait, Many CausesSECTION 7: The Human Genome Landscape
  25. The Human Genome Project
  26. There’s Cloning and Then There’s Cloning
  27. The Human Genome Sequence
  28. Finding Genes in the Human GenomeSECTION 8: Complex and Heterogeneous Traits
  29. Genotype Phenotype Correlations
  30. How Complex Can It Get?
  31. Quantitative Traits
  32. The MAOA Gene: Is There a Genetic Basis for Criminality?
  33. The Multiple-Hit Hypothesis: The Genetics of CancerSECTION 9: Genetic Testing and Therapy
  34. Genetic Testing and Screening
  35. Magic Bullets: The Potential for Gene TherapySECTION 10: Fears, Faith, and Fantasies
  36. Heroes Among Us
  37. Fears, Faith, and Fantasies Credits Index

Details

No. of pages:
480
Language:
English
Copyright:
© Academic Press 2005
Published:
Imprint:
Academic Press
eBook ISBN:
9780080474588

About the Author

Julia Richards

Julia Richards

Julia E. Richards (PhD, Genetics, University of Wisconsin) is Professor of Ophthalmology and Visual Sciences and Professor of Epidemiology at the University of Michigan in Ann Arbor where she teaches introductory genetics to graduate students in the School of Public Health. She is widely known for her research on inherited eye diseases and has published numerous chapters and research articles focused on human genetics.

Affiliations and Expertise

University of Michigan, Ann Arbor, MI

R. Scott Hawley

R. Scott Hawley (PhD, Genetics, University of Washington) is an American Cancer Society Research Professor and Investigator at the Stowers Institute for Medical Research. He has served as President of the Genetics Society of America in 2010 and in 2008 he received that society's Elizabeth W. Jones Award for Excellence in Teaching. He widely known for his teaching, for his research on meiosis and for the authorship of numerous textbooks and research papers.

Affiliations and Expertise

Stowers Institute for Medical Research, Kansas City, MO

Reviews

"This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absord its basic implications." -BIOWORLD, 2006 "The clarity of writing and thought in The Human Genome, A User's Guide makes an understanding of genetics and its impact in modern society accessible to everyone." -Bruce Chase, University of Nebraska at Omaha "It is easy to read, well thought-out, and full of good examples that clearly explain some of the more difficult concepts in modern genetics." -Richard K. Wilson, Washington University "The authors have done a superb job of identifying the key concepts and breaking them down into understandable and relevant explanations..." -Neil Lamb, Emory University "This is an excellent version of classical human genetics for sophomore level science students or for all levels of non-science majors." -John Merriam, University of California at Los Angeles "It is enjoyable to read, clear, and accurate... The first edition was excellent but this one is even better." -Philip Meneely, Haverford College