The Hallucinogens

PrefaceChapter I. Plant ß-Phenethylamines Introduction Mescaline Mescaline Analogs Amphetamines Methylenedioxyamphetamines Asarone Kava Kava Safrole Sympathomimetic Amines ReferencesChapter II A. d-Lysergic Acid Diethylamide Introduction Sources of LSD Chemistry of LSD Pharmacology Biochemistry of LSD Neurophysiological Effects Comparison of Some Ergot Alkaloids for Psychotomimetic Activity Toxicology of LSD Complications When LSD is Given Dose and Psychological Activity Effect of LSD on Normal Subjects Psychotomimetic Reaction to LSD The Psychedelic Experience Effect of LSD on Schizophrenic Patients Use of LSD in Psychotherapy Rapid Personality Change and LSD Criticisms of LSD Therapy and Rebuttal Modifiers of the LSD Experience How Does LSD Work Some Consequences of LSD's Introduction to PsychiatryChapter II B. Ololiuqui: The Ancient Aztec Narcotic History and Identification Taxonomy of Convolvulaceae Containing Ergot Alkaloids Chemistry Psychological Properties ReferencesChapter III. Adrenochrome and Some of Its Derivatives Introduction Chemistry Chemical Properties Biochemical Properties Formation and Metabolism of Adrenochrome Psychological Properties of Adrenochrome Adrenolutin Prolonged Reactions to Adrenochrome and Adrenolutin Anxiety and Adrenochrome Anxiety and Adrenolutin 5,6-Dihydroxy-N-Methylindole Adrenochrome Monosemicarbazone ReferencesChapter IV. Indole Hallucinogens Derived from Tryptophan Introduction Tryptophan Tryptamine Cohoba, the Narcotic Snuff of Ancient Haiti Dimethyl- and Diethyltryptamines Effect of Bufotenine, Dimethyltryptamine (DMT), and Diethyltryptamine (DET) on Animal Behavior Cross-Tolerance of DMT α-Methyltryptamine α-Ethyltryptamine Methyl-2-Methyltryptamine Iboga Alkaloids Harmine Psilocybin Yohimbine How Tryptamine Hallucinogens Act Serotonin Drugs and Central Serotonin or Noradrenaline ReferencesChapter V. Hallucinogens Related to Parasympathetic Biochemistry Introduction Factors Which Produce Synaptic Depression Factors Which Produce Excitation Acetylcholine Acetylcholinesterase Anticholinesterases as Hallucinogens Cholinergic-Blocking Hallucinogens Benactyzine Cholineacetylase Inhibitors as Antihallucinogens Anesthetic Hallucinogens ReferencesChapter VI. Taraxein Introduction Biochemistry of Taraxein Psychological Properties How Does Taraxein Work ReferencesChapter VII. Animal Studies of Hallucinogenic Drugs Introduction Studies in Invertebrates Lower Vertebrates Higher Vertebrates General Effect of Hallucinogenic Drugs Introduced Intrasystemically Intracerebral Effect of Hallucinogenic Drugs Behavioral Correlates of Electrophysiological Effects of Hallucinogens Effects of Hallucinogenic Drugs on Learning and Other Higher Cognitive Functions Summary and Conclusions ReferencesAuthor IndexSubject Index