The Gene Knockout Factsbook, Two-Volume Set

1st Edition

Editor-in-Chiefs: Tak Mak
Hardcover ISBN: 9780124660441
eBook ISBN: 9780080532363
Imprint: Academic Press
Published Date: 26th October 1998
Page Count: 1140
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Table of Contents

5-HT1B. 5-HT2c. ACE. ACP5. AROSIN. ACTIVIN REC TYPE II. ACTIVIN/INHIBIN BETA B. ACTIVIN/INHIBIN BETA A. Ada. Ae1. AGA. AGT. AGTR1A. AGTR2. AHR. Alox12p. Alpha Galactosidase. Alpha Lactalbumin. Alpha-Globin. Alpha-Inhibin. Alx-4. AML-1. ANP. Ant1. AP-2. Apo A-1. ApoA-II. ApoB. Apobec-1. ApoC-I. ApoC-III. ApoE. APP. APRT. ARNT. ASGPR2. Asmase. ASS. ATF-2. B7.1. B7.2. Bax. Bcl-x. Bcl2. Bcl6. Bcr. BDNF. Beta C Chain. Beta IL-3. Beta-2 Microglobulin. BETA-CATENIN. BF-1. BF-2. BK2R. BMP1. BMP2. BMP4. BMP7. Bmp8a. Bmp8b. BMPR. Brca1. Brca2. C-erb Aalpha. C-kit. C-mpl. C-rel. C-ROS. C/EBP a. C/EBP beta (NF-IL6). C/EBP delta. C3. C5aR. Calbindin. Calretinin. CART HOMEOPROT1. Casein-Beta. CBFA1. Cbfb. CBS. CCHB1. CCR2. CCR5. CD11a. CD11Bcd14. Cd19. CD1d1. CD22. CD23. CD24. CD28. CD3 Epsilon. CD3 Eta.<BR


The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference.

Key Features

@introbul:Key Features @bul:* Entries provide information on:

  • general description of the protein and its function
  • gene symbol and database accession number
  • knockout construct
  • mouse phenotype
  • key references


Geneticists and life scientists in all branches, particularly immunologists, cell and developmental biologists, neuroscientists, and molecular biologists.


No. of pages:
© Academic Press 1998
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Editor-in-Chiefs

Tak Mak Editor-in-Chief

Tak W. Mak is the Director of the Campbell Family Institute for Breast Cancer Research in the Princess Margaret Hospital, Toronto, Canada, and a University Professor in the Departments of Medical Biophysics and Immunology, University of Toronto. He was trained at the University of Wisconsin in Madison, the University of Alberta, and the Ontario Cancer Institute. He gained worldwide prominence in 1984 as the leader of the team that first cloned the genes of the human T cell antigen receptor. His group went on to create a series of genetically altered mice that have proved critical to understanding intracellular programs governing the development and function of the immune system, and to dissecting signal transduction cascades in various cell survival and apoptotic pathways. His current research remains centered on mechanisms of immune recognition/regulation, malignant cell survival/death, inflammation in autoimmunity and cancer, and metabolic adaptation in tumor cells. Dr. Mak has published over 700 papers and holds many patents. He has been granted honorary doctoral degrees from universities in North America and Europe, is an Officer of the Orders of Canada and Ontario, and has been elected a Foreign Associate of the National Academy of Sciences (U.S.), a Fellow of the Royal Society of London (U.K.), and a Fellow of the AACR Academy. Dr. Mak has won international recognition as the recipient of the Emil von Behring Prize, the King Faisal International Prize for Medicine, the Gairdner Foundation International Award, the Sloan Prize of the General Motors Cancer Foundation, the Novartis Prize in Immunology, the Robert Noble Prize, the Killam Prize, the Stacie Prize, the McLaughlin Medal, and the Paul Ehrlich and Ludwig Darmstaedter Prize.

Affiliations and Expertise

The Campbell Family Institute for Breast Cancer Research, Ontario, Canada