The Flaviviruses: Detection, Diagnosis and Vaccine Development

The Flaviviruses: Detection, Diagnosis and Vaccine Development

1st Edition - December 12, 2003

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  • Editors: Thomas Chambers, Thomas Monath
  • Hardcover ISBN: 9780120398614
  • eBook ISBN: 9780080493831

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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Detection, Diagnosis and Vaccine Development, the third volume of The Flaviviruses details the current status of technologies for detection and differentiation of these viruses, their use in surveillance and outbreak investigation, and also reviews the latest clinical research.

Key Features

  • Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions
  • Descibes the technologies that have contributed to our current knowledge about the Flaviviruses
  • Identifies the major problems faced in understanding the virus-host interactins that result in disease
  • An exhaustive compendium of current and past knowledge on the Flavivirus family


Virologists, molecular epidemologists, clinicians and public health specialists, immunologists, and researchers in vaccine development

Table of Contents

  • Diagnosis and Surveillance
    Serodiagnosis of Flaviviral Infections and Vaccinations in Humans
    Molecular amplification assays for the detection of Flaviviruses
    Virus Epidemiology, Ecology and Emergence
    Japanese Encephalitis
    Epidemiology of St Louis encephalitis virus
    West Nile Virus: epidemiology and Ecology in North America
    Dengue Epidemiology: Virus Epidemiology, Ecology and Emergence.
    Epidemiology and Ecology of Yellow Fever virus
    Virus Epidemiology, Ecology and Emergence of Tick-borne flaviviruses
    Vaccines and Antiviral Agents
    Formalin-inactivated whole virus and recombinant subunit flavivirus vaccines
    Empirically derived live, attenuated vaccines against Dengue and Japanese Encephalitis
    DNA vaccines for Flaviviruses
    Chimeric Flaviviruses: novel vaccines against dengue fever, tick-borne encephalitis and Japanese encephalitis
    Prospects for antiviral therapy

Product details

  • No. of pages: 577
  • Language: English
  • Copyright: © Academic Press 2003
  • Published: December 12, 2003
  • Imprint: Academic Press
  • Hardcover ISBN: 9780120398614
  • eBook ISBN: 9780080493831

About the Serial Volume Editors

Thomas Chambers

Thomas Monath

Affiliations and Expertise


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