The Eye, Volume 4

The Eye, Volume 4

1st Edition - February 1, 2023

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  • Editors: Ahmed El-Hashash, Eman Taher, Mohamed Elalfy
  • Paperback ISBN: 9780323999878

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The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.

Key Features

  • Provides cutting-edge research to understand stem cell functions used in disease treatments of the eye
  • Develops processes to bring stem cells from bench to bedside
  • Includes up-to-date references on stem cell biology and function in common eye diseases and disorders


Stem cell biology scientists, regenerative medicine scientists, physicians and surgeons, Graduate and undergraduate students, researchers and practitioners in these fields; Biomedicine, stem cell biology, regenerative medicine, and joint and bone biology, repair and regeneration, as well as translational regenerative medicine courses in the biomedical, biological and stem cell-related programs; These relevant courses are taught at schools of medicine, basic medicine and life sciences at a wide range of universities in the U.S. (e.g., University of South California), Europe (e.g. University of Edinburgh, Manchester, etc.), South East Asia (e.g. Zhejiang University, China) etc.

Table of Contents

  • Cutting edge Research on the Eye stem cell functions
    1. Organoid-based modality of Eye function and cellular processes
    2. Organoid culture system in Eye Development and Pathogenesis and genetic screening

    Cutting edge Research on stem cell application in the lung diseases (from bench to bed)
    3. Stem Cell-Based Organoid Culture
    4. Contributions of Stem Cell Engineering to New Therapies of Eye Diseases
    5. Preclinical and Clinical Applications of Innovative Gene Editing Technologies
    iPSCs as an Inexhaustible Source of Disease
    6. The Gold Standard Embryonic Stem Cells in Eye Regeneration and Diseases
    7. Preclinical and Clinical Applications Mesenchymal Stem/Stromal Cells in Eye Diseases
    8. Update on Stem/Progenitor Cell-based Clinical Trials of Eye Disorders – New chapter added per reviewer suggestion

Product details

  • No. of pages: 200
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: February 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323999878

About the Editors

Ahmed El-Hashash

Dr. El-Hashash is a fellow of the California Institute of Regenerative Medicine and New York University Medical School. Prof. El-Hashash worked as a senior biomedical research scientist at Mount Sinai School of Medicine of New York University and Children’s Hospital Los Angeles. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at Keck School of Medicine and Ostrow School of Dentistry of The University of Southern California. In 2016, Prof. El-Hashash joined The University of Edinburgh, Edinburgh Medical School-Zhejiang International Campus, as Tenure-Track Associate Professor and Senior Principal Investigator of Biomedicine, Stem Cell & Regenerative Medicine. Prof. El-Hashash has several breakthrough discoveries in genes/enzymes that control stem cell behavior and regenerative medicine and has published more than 25 papers in international journals and serves as an editorial board member of repute. He is the editor or author of several books on stem cell and regenerative medicine.

Affiliations and Expertise

The University of Edinburgh-Zhejiang International Campus, China and Edinburgh University Medical School, UK and Zhejiang University Schools of Medicine and Basic Medicine, China

Eman Taher

Dr. Eman E. Taher is a Professor in the Department of Microbiology and Clinical Parasitology at the Research Institute of Ophthalmology. The institute studies and performs different diagnostic techniques for parasites especially those affecting the eyes. Dr. Taher is the head of the Clinical Parasitology Unit. His extensive work has been on the diagnosis of Acanthamoeba, Toxoplasma, Toxocara and Schistosomiasis, as well as other different parasites, which has yielded over 20 papers, with different faculties, post-doctoral fellows and students. Additionally, Dr. Taher has also completed extensive research on different molecular diagnostic techniques for different parasites including electrophoresis, PCR, Western blot, DNA-extraction, ELISA and dot-ELISA. In addition, to stem cell preparation, characterization being a member of the stem cell laboratory at the Research Institute of Ophthalmology, he earned a six–month scholarship at the Eye and Ear Institute, Pittsburgh University, USA. His research portfolio includes variable papers on different parasites.

Affiliations and Expertise

Professor, Department of Microbiology and Clinical Parasitology, Research Institute of Ophthalmology, Cairo, Egypt

Mohamed Elalfy

Dr. Mohamed Elalfy is a fellow of the Royal College of Ophthalmologists in London, the Royal College of Surgeons in Edinburgh, the Royal College of Physicians and Surgeons in Glasgow, the European Board of Ophthalmology and the International Council of Ophthalmology. He is an active member of the European Society of Cataract and Refractive Surgery, and of The European Cornea Society and Refractive Surgery. Mr Elalfy travels abroad as an invited guest to share his expertise through teaching and live surgeries. He is Fellowship Programme Director in Corneoplastic Unit, Queen Victoria Hospital where he trains four fellows annually. Having obtained two academic qualifications through his career of more than 15 years in ophthalmology and with more than 30 peer-reviewed publications, Mr Elalfy puts evidence-based ophthalmology in the heart of his practice.

Affiliations and Expertise

Ophthalmologist - Private Practice, UK

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