
The Exposome
A Primer
Description
Readership
Table of Contents
Dedication
Preface
Chapter 1. The Exposome: Purpose, Definition, and Scope
1.1 Why a Primer?
1.2 What is the Exposome?
1.3 Darwin Would Be Proud
1.4 If it is So Obvious, Why This Book?
1.5 Environmental Health Practitioners
1.6 The Exposome as an Educational Tool
1.7 Discussion Questions
Further Reading
Chapter 2. When the Genome Falls Short: Limitations of a Gene-Centric View of Health
2.1 DNA, No Longer a Secret
2.2 The Gene Versus Environment Continuum
2.3 A Dangerous Metaphor?
2.4 ENCODE Project
2.5 Epigenetics: A Clear Gene–Environment Interface
2.6 Obstacles and Opportunities
2.7 Discussion Questions
Further Reading
Chapter 3. The Explosion of -Omic-Based Technology and its Impact on the Exposome
3.1 The Science of “Me, Too”
3.2 Transcriptome
3.3 Proteome
3.4 Pharmacogenomics/Toxicogenomics
3.5 Epigenomics
3.6 Metabolome
3.7 Microbiome
3.8 What to Do with All of These -Omes
3.9 What Type of Omic is the Exposome?
3.10 Obstacles and Opportunities
3.11 Discussion Questions
Further Reading
Chapter 4. The Exposome in Environmental Health Sciences and Related Disciplines
4.1 Welcome Home Exposome
4.2 Toxicology—Mechanisms of Toxicity
4.3 Exposure Science (or Assessment, or Biology)
4.4 Epidemiology and the Exposome
4.5 Global Epidemiology
4.6 Pesticides as an Example of Strained Relationships
4.7 Obstacles and Opportunities
4.8 Discussion Questions
Further Reading
Chapter 5. Managing and Integrating Exposome Data: Maps, Models, Computation, and Systems Biology
5.1 Maps, Models, and Technology
5.2 Mapping
5.3 Big Data, Really Big
5.4 I am so Smart, S-M-R-T
5.5 Mathematical Modeling
5.6 Models
5.7 Predicting Predictions
5.8 Obstacles and Opportunities
5.9 Discussion Questions
Further Reading
Chapter 6. The Practical Exposome: Education at the University and Community Level
6.1 Immediate Practical Utility
6.2 The Modifiable Exposome
6.3 Behaviors, Mandates, and Nudges
6.4 Academic Education: The Exposome in the Ivory Tower
6.5 Introducing the Exposome as a Single Lecture
6.6 The Exposome as a Unit Within a Course
6.7 The Exposome as the Basis for an Entire Course
6.8 The Exposome Outside of the Classroom
6.9 Obstacles and Opportunities
6.10 Discussion Questions
Further Reading
Chapter 7. Staging the Exposome: A Vision for International Collaboration
7.1 Measuring the Exposome
7.2 What is in Us? What is Near Us? Does it Matter?
7.3 A Basis in Biology
7.4 It Has Already Started
7.5 So What are the Exposome Deliverables?
7.6 Gene × Environment × Grants
7.7 An Exposome Index
7.8 A Human Exposome Project?
7.9 Obstacles and Opportunities
7.10 Discussion Questions
Further Reading
Product details
- No. of pages: 118
- Language: English
- Copyright: © Academic Press 2013
- Published: November 16, 2013
- Imprint: Academic Press
- Paperback ISBN: 9780124172173
- eBook ISBN: 9780124172180
About the Author
Gary Miller

Affiliations and Expertise
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
KyungTaek R. Fri Mar 16 2018
Exposome
Good to read and so helpful.