Key Features

  • Provides the expertise of new contributors and volume editors who are world-class authorities in the field for authoritative guidance.
  • Features thoroughly updated content including new chapters—Seizure Prediction; Drug Resistance Genes; Cortical Myoclonus and Epilepsy; Sudden Unexplained Death in Epilepsy; Seizures in the Elderly; Rasmussen’s Encephalitis; Epilepsies Due to Monogenic Disorders of Metabolism; Epilepsy and Sleep; Long-term Effects of Seizures on Brain Structure and Function; Brain Stimulation in Epilepsy—for the most current information for use in the decision-making process.
  • Includes coverage of the surgical management of epilepsy to help you determine when it’s best to recommend surgery and for which patients.
  • Emphasizes pharmacologic management of seizure patients that reflects advances in biotechnology and imaging.

Table of Contents

1 Seizure Prediction: Its Evolution and Therapeutic Potential, David Krieger and Brian Litt

2 Febrile Seizures, Céline M. Dubé and Tallie Z. Baram

3 Mechanisms of Action of Levetiracetam and Newer SV2A Ligands, Henrik Klitgaard and Alain Matagne

4 Long-Term Effects of Seizures on Brain Structure and Function, Howard P. Goodkin and Edward H. Bertram

5 Dipole Source Modeling in Epilepsy: Contribution to Clinical Management, John S. Ebersole

6 EEG-correlated fMRI in Epilepsy: Current State of the Art, Rachel Thornton and Louis Lemieux

7 Epilepsy and Sleep, Soheyl Noachtar and Jan Rémi

8 Cortical Myoclonus and Epilepsy: Overlap and Differences, Renzo Guerrini and Francesco Mari

9 The Life-Threatening Epilepsies of Childhood and Their Treatment, Catherine Chiron

10 The Spectrum of Epilepsies Associated with Generalized Spike and Wave Patterns, Michael Koutroumanidis and Chrysostomos P. Panayiotopoulos

11 Epilepsies due to Monogenic Disorders of Metabolism, Chantal Depondt

12 Rasmussen’s Encephalitis, Tiziana Granata and Carlo Antozzi

13 Seizures and Epilepsy in the Elderly, Anil Mendiratta and Timothy A. Pedley

14 Psychosis of Epilepsy, Andres M. Kanner

15 Sudden Unexpected Death in Epilepsy, Fergus J Rugg-Gunn and Lina Nashef

16 The Management of Epilepsy in Pregnancy, Torbjörn Tomson and Dina Battino

17 Does Early Treatment Influence the Long-Term Outcome of Epilepsy?, A.G. Marson

18 Pharmacodynamic Interactions of Antiepileptic Drugs, Gail D. Anderson and Jong M. Rho

19 The Surgery of Temporal Lobe Epilepsy I – Historical Development, Patient Selection, and Seizure Outcome, Nicholas Moran and Simon Shorvon

20 The Surgery of Temporal Lobe Epilepsy II – Surgical Complications and Long-Term Adverse Effects, Simon Shorvon and Nicholas Moran

21 Brain Stimulation in Epilepsy – An Old Technique with a New Promise?, Kristl Vonck and Paul


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© 2009
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About the editors

Simon Shorvon

Affiliations and Expertise

Professor in Clinical Neurology, Institute of Neurology, Consultant Neurologist, National Hospital for Neurology and Neurosurgery and Medical Director, National Society for Epilepsy, London, UK

Timothy Pedley

Affiliations and Expertise

Professor and Vice-Chairman, Department of Neurology, College of Physicians and Surgeons of Columbia University; Director, Columbia Comprehensive Epilepsy Center, NY, USA