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The Epidemiology of Plasmodium Vivax: History, Hiatus and Hubris - 1st Edition - ISBN: 9780123979001, 9780123979117

The Epidemiology of Plasmodium Vivax: History, Hiatus and Hubris, Volume 80

1st Edition

Serial Volume Editors: Ric Price J. Kevin Baird S.I. Hay
eBook ISBN: 9780123979117
Hardcover ISBN: 9780123979001
Imprint: Academic Press
Published Date: 21st December 2012
Page Count: 368
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Table of Contents

  • Series Editors
  • Contributors
  • Preface
  • Chapter One. The Global Public Health Significance of Plasmodium vivax
    • 1 Introduction
    • 2 The Global Distribution of P. vivax Infections
    • 3 Spatial Distribution of P. vivax Malaria, Populations at Risk and Its Vectors
    • 4 Regional Summaries of the Public Health Significance of P. vivax Malaria
    • 5 Discussion
    • 6 Methods
    • References
  • Chapter Two. Relapse
    • 1 Introduction
    • 2 History
    • 3 Phenotypic Variation in P. vivax
    • 4 Relapse Determinants
    • 5 Geographic Distribution of Relapse Phenotypes
    • 6 The Effects of Age and Immunity on Relapse
    • 7 Drug Effects on Relapse
    • 8 Vivax Malaria Following Falciparum Malaria
    • 9 The Periodicity of Relapse
    • 10 Implications for Epidemiological Assessment
    • References
  • Chapter Three. Plasmodium vivax
    • 1 Introduction
    • 2 Pre-patent and Incubation Periods
    • 3 Symptoms and Signs of Vivax Malaria
    • 4 Clinical Illness Requiring Hospitalisation
    • 5 Severe Malaria
    • 6 Risk of Severe Disease and Death
    • 7 Vulnerable Groups
    • 8 Specific Clinical Manifestations of Severe Vivax Malaria
    • 9 Severe and Fatal Disease Resulting from Treatment with Primaquine
    • 10 Risk Factors for Uncomplicated and Severe Vivax Malaria
    • 11 Pathophysiology of Disease in Vivax Malaria
    • 12 Conclusion
    • References
  • Chapter Four. Diagnosis and Treatment of Plasmodium vivax Malaria
    • 1 Introduction
    • 2 Chemotherapeutics Terminology
    • 3 Historical Perspectives
    • 4 Chemoprophylaxis Against Vivax Malaria
    • 5 Diagnosis of Vivax Malaria
    • 6 Treatment of Uncomplicated Vivax Malaria
    • 7 Treatment of Severe and Complicated Vivax Malaria
    • 8 Evaluating Drug Resistance in Vivax Malaria
    • 9 Research and Development Urgencies
    • 10 Summary
    • References
  • Chapter Five. Chemotherapeutic Strategies for Reducing Transmission of Plasmodium vivax Malaria
    • 1 Introduction
    • 2 Transmission of P. vivax
    • 3 Reducing P. vivax Transmission by Treating Symptomatic Disease
    • 4 Reducing P. vivax Transmission Using Mass Drug Administration
    • 5 Conclusions
    • References
  • Chapter Six. Control and Elimination of Plasmodium vivax
    • 1 Why Controlling P. vivax Is Difficult
    • 2 Established Anti-transmission Measures
    • 3 Drugs for Control of Relapsing Malaria
    • 4 Difficulty Going from Low to No Malaria Transmission
    • 5 Surveillance as Key Intervention for Malaria Elimination
    • 6 Problems of Malaria Reintroduction into Eliminated Areas
    • 7 Prospects for Improved Drugs for Control/Elimination
    • 8 Prospects for Improved Anti-transmission Measures
    • 9 Conclusions
    • References
  • Index


First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology.

Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.

Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2010 impact factor is1.683.

Key Features

  • Informs and updates on all the latest developments in the field
  • Contributions from leading authorities and industry experts


Researchers in parasitology, tropical medicine and entomology


No. of pages:
© Academic Press 2012
21st December 2012
Academic Press
eBook ISBN:
Hardcover ISBN:


"One is struck by the quality and scholarship of the various chapters and the obviously efficient editing." --Parasitology

"The policy of the editors of Advances in Parasitology to include reviews from any aspect of parasitology and the high standard of individual papers have resulted in this series of volumes becoming an indispensable source for students, teachers, and research workers." --Annals of Tropical Medicine and Parasitology

Ratings and Reviews

About the Serial Volume Editors

Ric Price

J. Kevin Baird

S.I. Hay

Affiliations and Expertise

Professor of Epidemiology, Spatial Epidemiology and Ecology Group, Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, U.K.