The Endocrine Function of the Human Testis - 1st Edition - ISBN: 9780123801012, 9781483257907

The Endocrine Function of the Human Testis

1st Edition

Editors: V. H. T. James M. Serio L Martini
eBook ISBN: 9781483257907
Imprint: Academic Press
Published Date: 1st January 1973
Page Count: 602
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Description

The Endocrine Function of the Human Testis, Volume 1, contains papers that comprise the series of lectures given in a short course on the "Endocrine Function of the Human Testis" which was organized by the Post-Graduate School of Endocrinology in the University of Florence. The course was held in two parts, the first on April 25-27 and the second on October 24-26, 1972. The topics which were covered were: methods for the assay of androgens; binding of androgens in plasma; metabolism of testosterone; the chemistry, biology, and radioimmunoassay of hypophiseal gonadotrophins; the mechanism of control of the secretion of pituitary gonadotrophins; and the biosynthesis of androgens in the human testis.

Table of Contents


Preface

Determination of Androgens in Human Plasma

Methodologic Considerations on the Measurement of Plasma Androgens by Competitive Protein Binding Methods and Radio-Assays

Problems Connected with Steroid Radioimmunoassay

Mathematical Analysis of the Results of Competitive Binding Methods

Determination of Androgens in Plasma

Determination of Testosterone in Peripheral and Spermatic Venous Plasma by a Competitive Protein Binding Method

Gas Chromatographic Determination of Plasma Testosterone

Elements of a Forward Approach to the Mechanism of Androgen Action

The Physical State of Testosterone in Plasma

Mathematical Models for the Study of Androgen Metabolism

The Metabolic Clearance Rate and the Metabolism of Testosterone

Recent Data on the Chemistry of Human Gonadotropins

Immunochemical and Biological Nature of Gonadotrophin Subunits

Aspects of the Mechanism of Action of Gonadotrophins

Radioimmunoassays of Gonadotropins

Characteristics of a Solid Phase Method for FSH and LH

Sexual Differentiation of the Hypothalamic "Prolactin Inhibiting Factor Center" and Other Brain Areas

Organizing Effects of "Early" Testosterone Secretion on Steroid Metabolism and Binding

Mechanisms Which Control Puberty in Males

The Hypothalamic Gonadotrophin Releasing Factors

In Vitro Methods for the Study of Releasing Hormones

Synthetic Gonadotropin Releasing Hormone: A Powerful Tool for the Clinician

Feedback Activity of Testosterone and of Its 5a-Reduced Metabolites Human Gonadotrophin Secretion in Male Subjects

Regulation of the Production of Testicular Steroids

Androgen Dependency of Spermatogenesis and the Physiological Significance of Steroid Metabosism In vitro by the Seminiferous Tubules

Biochemical Functions of Isolated Interstitial Tissue and Seminiferous Tubules from Rat Testis

Evaluation of Male Infertility by Dynamic Tests

Subject Index


Details

No. of pages:
602
Language:
English
Copyright:
© Academic Press 1973
Published:
Imprint:
Academic Press
eBook ISBN:
9781483257907

About the Editor

V. H. T. James

M. Serio

L Martini