The enormity of the literature on growth factors, plus the breadth of the biological disciplines and technical expertise required prohibits a comprehensive review by even a multi-disciplinary panel of authors. To provide an alternative that is feasible for authors and digestible by readers, this review compendium consists of a collection of articles, each covering an aspect of teh ErbB/EGF field. This compilation features articles on growth factor ligands, neuregulins, and individual receptors. The second part of the book concentrates on the biological context of the ErbB receptors, particularly in mammary development and in cancer. It concludes with a discussion of the genetic systems that have enabled significant advances in research in this area.
Cancer researchers, oncologists, cell biologists, pharmacologists, neurologists, and biochemists.
EGF Receptor Ligands
Neuregulins: Functions, Forms, and Signaling Strategies
Epidermal Growth Factor Receptor: Mechanisms of Activation and Signaling
The Deaf and Dumb: The Biology of ErbB-2 and ErbB-3
ErbB-4: Mechanism of Action and Biology
Trafficking of the ErbB Receptors and Its Influence on Signaling
Erbbs in Mammary Development
The ErbB Receptors and their Role in Cancer Progression
Ligand-Independent Oncogenic Signaling by the Epidermal Growth Factor Receptor: V-ErbB as a Paradigm
ErbB-Targeted Therapeutic Approaches in Human Cancer
Mechanism of Action of erbB Tyrosine Kinase Inhibitors
Signaling by the Drosophila Epidermal Growth Factor Receptor Pathway during Development
The Epidermal Growth Factor System in Caenorhabaditis Elegans
- No. of pages:
- © Academic Press 2003
- 19th December 2003
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
Vanderbilt University, Nashville, TN, U.S.A.