
The DNA Replication-Repair Interface
Description
Key Features
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in Methods in Enzymology series
- Includes the latest information on replication-coupled repair
Readership
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists
Table of Contents
Preface
Brandt F. Eichman
1. Eukaryotic DNA replication with purified budding yeast proteins
John Diffley
2. Monitoring the replication of structured DNA through heritable epigenetic change
Julian Sale and Guillaume Guilbaud
3. Visualizing replication fork encounters with DNA interstrand crosslinks
Michael Seidman
4. Single-molecule imaging of replication fork conflicts at genomic DNA G4 structures in human cells
Eli Rothenberg, Dipika Gupta and Wei Ting C. Lee
5. Studying the DNA damage response in embryonic systems
Domenico Maiorano, Elena Lo Furno, Bénédicte Recolin, Siem van der Laan and Antoine Aze
6. Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast
Andrés Aguilera
7. Determining the kinetics of break-induced replication (BIR) by the assay for monitoring BIR elongation rate (AMBER)
James E. Haber
8. Genomic mapping of DNA reaction intermediates in living cells with engineered DNA structure-trap proteins
Susan Rosenberg, Jingjing Liu and Qian Mei
9. A mapping platform for mitotic crossover by single-cell multi-omics
Yi Yin
10. Characterization of DNA-PK-bound end fragments using GLASS-ChIP
Tanya Paull
11. Light activation and deactivation of Cas9 for DNA repair studies
Taekjip Ha and Roger Zou
12. A Detection method for the capture of genomic signatures: from disease diagnosis to genome editing
Pierre Billon, Orléna Benamozig and Lou Baudrier
13. A method to sequence genomic sites of mitotic DNA synthesis in mammalian cells
Thanos Halazonetis, Jonathan Mailler and Laura Padayachy
14. Loop-seq: a high-throughput technique to measure the mesoscale mechanical properties of DNA
Aakash Basu
15. Characterization of the telomerase modulating activities of yeast DNA helicases
Matthew Bochman
16. Single-molecule studies of yeast Rad51 paralogs
Eric Greene and Upasana Roy
17. Synthesis and polymerase bypass studies of DNA-peptide and DNA-protein conjugates
Natalia Tretyakova and Suresh S. Pujari
18. Chemistry and structural screen integrated efficiently for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2
John Tainer, Davide Moiani, Susan Tsutakawa, Youngchang Kim, Todd Link, Chris Brosey, Panagiotis Katsonis, Olivier Lichtarge, Andrzej Joachimiak, Zhijun Ma, In-Kwon Kim, Zamal Ahmed and Darin E. Jones
Product details
- No. of pages: 452
- Language: English
- Copyright: © Academic Press 2021
- Published: November 12, 2021
- Imprint: Academic Press
- eBook ISBN: 9780323907347
- Hardcover ISBN: 9780323907330
About the Serial Volume Editor
Brandt Eichman

Affiliations and Expertise
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