Development of Responsiveness to Steroid Hormones

1st Edition

Advances in the Biosciences

Editors: Alvin M. Kaye Myra Kaye
Hardcover ISBN: 9780080249407
eBook ISBN: 9781483153087
Imprint: Pergamon
Published Date: 18th February 1980
Page Count: 494
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Development of Responsiveness to Steroid Hormones is a collection of papers presented at the Bat-Sheva Seminar of the same name which was held in Rehovot, Israel, on October 18-26, 1978 and sponsored by the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel in cooperation with The Weizmann Institute of Science. Contributors explore how the steroid receptor complex modulates transcription of RNA and cover topics ranging from the sequential acquisition of responsiveness to estrogen in the rat uterus to the ontogeny of steroid receptors in the guinea pig.

This book is comprised of 29 chapters and begins with a review of estrogen and estrogen effects in rat uterus and pituitary in culture. The embryonic chick Müllerian duct and several fetal guinea pig organs are then considered, followed by discussions on mammalian and chick liver, multi-hormonal control in rat liver; progesterone and decidualization; and rat mammary gland in culture. Glucocorticoids in developing pancreas, lung, and liver are examined, along with ecdysteroids in both locusts and Drosophila. Refractoriness is exemplified by gonadotropin action in the ovary. The remaining chapters deal with the role of steroid hormone receptors in brain development; the neural trigger for ovulation; aromatization and development of responsiveness of the brain to gonadal steroids; and neuroendocrine correlates of female-offspring interaction in maternal rats.

This monograph will be of value to physiologists, biologists, and biochemists.

Table of Contents

Preface Sequential Acquisition of Responsiveness to Estrogen in the Rat Uterus Regulation of Prolactin Synthesis by Estrogen Rodent Alpha1-Fetoprotein and Its Interaction with Estrogens Influence of Rat Estradiol Binding Plasma Protein (EBP) On Estrogen Binding to Its Receptor and on Induced Biological Responses Ontogeny of the Receptor and Responsiveness to Estrogen in the Genital Tract of the Chick Embryo Ontogeny of Steroid Receptors in the Guinea Pig Estrogen Receptor in the Mammalian Liver: Developmental and Metabolic Aspects The Development of Estrogen Receptors and of the Vitellogenic Response to Estradiol in Embryonic Chick Liver Development of Hormonal Control of Histidase Functional Development of Rat Trophoblast and Decidual Cells during Establishment of the Hemochorial Placenta The Role of Progesterone in Induction of Decidualization in the Uterus of the Pseudopregnant Rat Modulation of Progesterone Metabolizing Enzyme in Lymphocytes during Development and By Endocrine Manipulation Alterations in Steroid-Responsiveness During Ontogeny of Mouse Mammary Epithelium Differential Response of Embryonic Chick Pancreas Enzymes to Glucocorticoids Glucocorticoids and Fetal Lung Development Developmental Changes in the Glucocorticoid Induction of Hepatic Tyrosine Aminotransferase Sequential Action of Ecdysone and 20-Hydroxyecdysone on Locust Epidermis Ecdysteroid Action in Imaginai Discs of Drosophila melanogaster Control By Estrogen of Reversible Gene Expression: the Vitellogenin Model Development of Refractoriness of the Ovarian Cyclic AMP System to Gonadotrophins Control of Responsiveness to Gonadotropins and Steroids in the Neonatal Rat Ovary Development of Ovarian Responsiveness: Follicle Maturation and Luteinization Receptors for Glucocorticosteroids in the Embryonic Neural Retina in Relation to the Development of the Biological Response Steroid Hormone Receptors during Brain Development The Neural Trigger For Ovulation - A Safety Cat


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About the Editor

Alvin M. Kaye

Myra Kaye