The Common Marmoset in Captivity and Biomedical Research

The Common Marmoset in Captivity and Biomedical Research

1st Edition - November 19, 2018

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  • Editors: Robert Marini, Lynn Wachtman, Suzette Tardif, Keith Mansfield, James Fox
  • Hardcover ISBN: 9780128118290
  • eBook ISBN: 9780128118306

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Description

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism.

Key Features

  • Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications
  • Includes contributions from renowned and international authors and editors
  • Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Readership

Vivarium professionals maintaining marmoset colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using them to gain critical insights into human physiology and disease

Table of Contents

  • Section I: BIOLOGY AND MANAGEMENT
    1. Taxonomy and Natural History
    2. The Anatomy of the Common Marmoset
    3. Neuroanatomy of the Marmoset
    4. Marmoset Nutrition and Dietary Husbandry
    5. Husbandry and Housing of Common Marmosets
    6. Normal Clinical and Biological Parameters of the Common Marmoset (Callithrix jacchus)
    7. Behavior and Behavioral Management
    8. Reproduction, Growth, and Development
    9. Regulatory Considerations

    Section II: DISEASES AND CLINICAL APPLICATIONS
    10. Physical Examination, Diagnosis, and Common Clinical Procedures
    11. Anesthesia and Common Surgical Procedures
    12. Diseases of the Urogenital System
    13. Diseases of the Gastrointestinal System
    14. Bone, Muscle, and Skeletal Disease
    15. Viral Diseases of Common Marmosets
    16. Bacterial Diseases
    17. Parasitic Diseases
    18. Neoplastic Diseases

    Section III: RESEARCH AND APPLICATIONS
    19. The Genome of the Common Marmoset
    20. Creating Genetically Modified Marmosets
    21. Marmosets in Aging Research
    22. The Marmoset Monkey as a Model for Visual Neuroscience
    23. Marmosets in Neurologic Disease Research: Parkinson’s Disease
    24. Experimental Autoimmune Encephalomyelitis in the Marmoset as a Translational Model for Multiple Sclerosis
    25. Marmosets in Auditory Research
    26. The Marmoset as a Model in Behavioral Neuroscience and Psychiatric Research
    27. The Use of the Marmoset in Toxicity Testing and Nonclinical Safety Assessment Studies
    28. Experimental Infections of the Common Marmoset (Callithrix jacchus)
    29. Insights Gained from Marmoset Endocrine Research

Product details

  • No. of pages: 570
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: November 19, 2018
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128118290
  • eBook ISBN: 9780128118306

About the Editors

Robert Marini

Robert P. Marini, DVM, DACLAM, Assistant Director, is a member of MIT’s Division of Comparative Medicine’s clinical staff and is Chief of the Division’s clinical surgical facilities. Dr. Marini is responsible for coordinating and supervising all major survival surgery in non-rodent mammalian species.

Affiliations and Expertise

MIT Division of Comparative Medicine, Cambridge, MA USA

Lynn Wachtman

Harvard Medical School, Boston MA USA

Affiliations and Expertise

Lynn M. Wachtman, DVM, MPH, is a clinical veterinarian and instructor in Pathology at Harvard Medical School.

Suzette Tardif

Suzette D. Tardif, Ph.D., is the Associate Director of Research at the Southwest National Primate Research Center. She is an adjunct faculty of The Barshop Institute. The Tardif laboratory's activities center on the development of the marmoset monkey as a disease model. Dr. Tardiff is a past-President of the American Society of Primatologists.

Affiliations and Expertise

Barshop Institute for Longevity & Aging Studies, San Antonio, TX USA

Keith Mansfield

Keith Mansfield is Associate Director for Resource and Collaborative Affairs and Chair, Division of Primate Resources, New England National Primate Research Center, Harvard Medical School, Harvard University, Southborough, US. His research focuses on primarily on the recognition of spontaneously occurring infectious diseases of nonhuman primates and their development into novel animal models to investigate disease pathogenesis.

Affiliations and Expertise

Novartis Institutes for Biomedical Research,Cambridge, MA, U.S.A.

James Fox

James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.

Affiliations and Expertise

Massachusetts Institute of Technology, Cambridge, MA, USA

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