The Clinical Biology of Sodium: The Physiology and Pathophysiology of Sodium in Mammals presents a comparative view of mammalian sodium regulation and its clinical disturbances. This book covers a wide range of topics, including the physiological basis of fluid therapy, oral rehydration for diarrhea, the pathogenesis of edema, hypovolemia, endocrine regulation and disturbances, and nutritional requirement.
Organized into 12 chapters, this book begins with an overview of the distribution and physiological functions of sodium. This text then explores the two processes that provide the basis of most of the non-endocrine functions of the kidneys, namely, glomerular filtration and tubular reabsorption of sodium. Other chapters consider the avoidable human and material costs of hypertension. This book discusses as well the molecular biology of sodium transport. The final chapter deals with the three mechanisms capable of detecting changes in cardiovascular filling.
This book is a valuable resource for doctors, nurses, and veterinarians.
1. Body Sodium in Context: Distribution, Functions and Regulation
Introduction: Some Problems in Context
Distribution and Concentration of Sodium
Sodium in Brain and Cerebrospinal Fluid
Functions of Sodium
Sodium Transport: Na-K ATPase
Factors Affecting Activity
2. Renal Sodium Regulation
Segmental Distribution of Sodium Reabsorption
Effects of Hypovolaemia
Endocrine Aspects of Renal Sodium Regulation
Loop of Henlé
Ascending Thick Limb
Regulation of ADH Release
Immaturity of Renal Function
3. Enteric Sodium Uptake
Enteric Sodium Transport
Enteric Sodium Regulation
Enteric Responses to Changes in Sodium Balance
Principles and Criteria of Efficacy
Sequestration: Third Space'
4. Behavioural Regulation of Sodium Intake
An Assumed Need, or a Real One?
Early Studies of Salt Appetite
Studies in Sodium-Depleted Sheep
1. Neural Aspects
- No. of pages:
- © Pergamon 1995
- 1st January 1995
- eBook ISBN:
- Hardcover ISBN: