The Cerebellum: From Structure to Control - 1st Edition - ISBN: 9780444823137, 9780080862392

The Cerebellum: From Structure to Control, Volume 114

1st Edition

Editors: C.I. De Zeeuw P. Strata J. Voogd
Hardcover ISBN: 9780444823137
eBook ISBN: 9780080862392
Imprint: Elsevier Science
Published Date: 23rd May 1997


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Table of Contents

List of contributors. Preface. Acknowledgements. I. Development and compartmentation of cerebellar cortex.

  1. Functional cloning of candidate genes that regulate purkinje cell-specific gene expression. 2. Transverse and longitudinal patterns in the mammalian cerebellum. 3. An anatomical model of cerebellar modules. II. Neurotransmission in cerebellar cortex. 4. The distribution of corticotropin-releasing factor (CRF), CRF binding sites and CRF1 receptor mRNA in the mouse cerebellum. 5. The physiological effects of serotonin on spontaneous and amino acid-induced activation of cerebellar nuclear cells: an in vivo study in the cat. 6. Cholinergic innervation and receptors in the cerebellum. 7. Molecular organization of cerebellar glutamate synapses. 8. Compartmentalised distribution of GABAA and glutamate receptors in relation to transmitter release sites on the surface of cerebellar neurons. III. Unipolar brush cells in cerebellar cortex. 9. The unipolar brush cells of the mammalian cerebellum and cochlear nucleus: cytology and microcircuitry. 10. Physiology of transmission at a giant glutamatergic synapse in cerebellum. IV. Anatomy and physiology of cerebellar nuclei. 11. Cerebellar nuclei: the olivary connection. 12. Functional significance of excitatory projections from the precerebellar nuclei to interpositus and dentate nucleus neurons for mediating motor, premotor and parietal cortical inputs. 13. Involvement of cerebellar cortex and nuclei in the genesis and control of unconditioned and conditioned eyelid motor responses. V. Pontocerebellar connections. 14. Salient anatomic features of the cortico-ponto-cerebellar pathway. 15. Mossy-fibre sensory input to the cerebellum. VI. Plasticity in olivocerebellar system. 16. Reciprocal trophic interactions between climbing fibres and purkinje cells in the rat cerebellum.
  2. Intrinsic properties and environmental factors in the regeneration of adult cerebellar axons. VII. Vestibulocerebellar coordination of movements.
  3. Signal processing in the C2 module of the flocculus and its role in head movement control. 19. Control of the three-dimensional dynamic characteristics of the angular vestibulo-ocular reflex by the nodulus and uvula. 20. Cholinergic control in the floccular cerebellum of the rabbit. 21. Behavioural analysis of purkinje cell output from the horizontal zone of the cat flocculus. VIII. Vestibulocerebellar learning. 22. Characterization of purkinje cells in the goldfish cerebellum during eye movement and adaptive modification of the vestibulo-ocular reflex. 23. Role of the y-group of the vestibular nuclei and flocculus of the cerebellum in motor learning of the vertical vestibulo-ocular reflex. IX. Cerebellar coordination of movements. 24. Aspects of cerebellar function in relation to locomotor movements. 25. The control of forelimb movements by intermediate cerebellum. 26. What features of visually guided arm movements are encoded in the simple spike discharge of cerebellar Purkinje cells. 27. Some organizing principles for the control of movement based on olivocerebellar physiology. 28. Is the cerebellum sensory for motors sake, or motor for sensorys sake: the view from the whiskers of a rat? X. Cerebellar learning and cognition.
  4. Cerebellar contributions to the acquisition and execution of learned reflex and volitional movements. 30. A new functional role for cerebellar long term depression. 31. On the role of the cerebellum and basal ganglia in cognitive signal processing. 32. Dentate output channels: motor and cognitive components. XI. Cerebellar diseases. 33. The genetic basis of hereditary ataxia. 34. Buspiron a serotonergic 5-HT1A agonist, is active in cerebellar ataxia. A new fact in favor of the serotonergic theory of ataxia. 35. Cerebellar somatotopic representation and cerebro-cerebellar interconnections. Subject index.


Many of the cerebellar scientists of the established generation have contributed substantially to the quality of this issue. In addition, the book is marked by chapters from the coming generations of scientists who will determine the direction of cerebellar research for the next century. As in other fields of neuroscience, this research will be dominated by molecular neurobiology and new functional imaging techniques. Altogether, the book is pluriform and unique in that it is multidisciplinary, in that it promotes different views on cerebellar function, and that it is being published on the verge of different era's dominated by different generations of cerebellar scientists. The wealth of new information and ideas contained in these important papers will stimulate even more intensive research in the twenty-first century leading to a greater understanding of cerebellar function(s).


© Elsevier Science 1997
Elsevier Science
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About the Editors

C.I. De Zeeuw Editor

Affiliations and Expertise

Department of Anatomy, Erasmus University Rotterdam, Dr. Molewaterplein 50, Rotterdam, The Netherlands

P. Strata Editor

Affiliations and Expertise

Human Anatomy and Physiology, University of Turin, Corso Raffaelo 30, Torino, Italy.

J. Voogd Editor

Affiliations and Expertise

Department of Anatomy, Erasmus University Rotterdam, Dr. Molewaterplein 50, Rotterdam, The Netherlands