The Cell Nucleus V2

The Cell Nucleus V2

1st Edition - January 1, 1974

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  • Editor: Harris Busch
  • eBook ISBN: 9780323145077

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The Cell Nucleus, Volume II covers mainly the chromosomes, including its pathology. It also reviews the information onthe isolated mitotic apparatus highlighting on its chemistryand relevant morphology. This volume particularly discusses the mammalian chromosomes, the staining techniques, the kinetics of DNA replication in chromosomes, and the difference of meiotic chromosomes from mitotic chromosomes. It also presents studies on isolated mammalian metaphase chromosomes; chromosomes of birds and plants; as well as the polytene chromosomes of the two-winged insects, the Diptera. Furthermore, this volume describes the giant chromosomes. Lastly, the autosomal disorders, the abnormalities of sex development, and types of virus-induced chromosome alterations are explained to elucidate the pathology of chromosome.

Table of Contents

  • List of Contributors


    Contents of Other Volumes


    Part I Chromosomes-General

    Chapter 1 Mammalian Chromosomes

    I. Introduction

    II. DNA Content, Chromosome Number, and Chromosome Morphology

    III. Sex Chromosomes

    IV. Heterochromatin

    V. Cytochemical Differentiation of Chromosomal Regions

    VI. Somatic Cell Hybridization

    VII. Chromosomes in Evolution


    Chapter 2 The Human Cell Nucleus: Quinacrine and Other Differential Stains in the Study of Chromatin and Chromosomes

    I. Perspectives on Human and Medical Cytogenetics

    II. Human Chromosome Identification

    III. Human Chromosome Polymorphisms

    IV. Study of Chromosome Abnormalities

    V. Chromosome Abnormalities in Malignancies

    VI. Paternity Studies

    VII. Parental Origin of Chromosome Abnormalities

    VIII. Gene Mapping Using Chromosome Polymorphisms, Rearrangements,

    and Somatic-Cell Hybridization

    IX. Chromatin: Differentially Marked Regions on Autosomes and the Y in Interphase

    X. Meiotic Chromosomes

    XI. Chromosome Evolution and Banding


    Chapter 3 Studies of Isolated Mammalian Metaphase Chromosomes

    I. Introduction

    II. Isolation of Metaphase Chromosomes

    III. Chemical Composition of Metaphase Chromosomes

    IV. Studies with Fractionated Metaphase Chromosomes

    V. The Structure of Metaphase Chromosomes

    VI. Conclusions


    Chapter 4 The Kinetics of DNA Replication in Chromosomes

    I. Introduction

    II. The Replicon

    III. The Replicon Series

    IV. The Chromosome

    V. Discussion

    VI. Conclusions


    Chapter 5 The Organization of Meiotic Chromosomes

    I. Introduction

    II. General Organization of DNA in Chromosomes

    III. Special Features of Meiotic Chromosomes

    IV. Relation of Chromosome Structure to Meiotic Chromosome Behavior

    V. Summary and Conclusions


    Chapter 6 Progress in Human Gene Mapping by Somatic Cell Hybridization

    I. Introduction

    II. Methodology and Rationale of Human Gene Mapping

    III. Assignments of Genes to Human Chromosomes

    IV. Regional Localization of Human Genes

    V. Conclusion


    Part II Chromosomes-Specific

    Chapter 7 Chromosomes of Birds

    I. Introduction

    II. Phylogeny of Birds and Genome Size

    III. Mitotic Chromosomes

    IV. Meiotic Chromosomes

    V. Heterochromatin

    VI. Heteroploidy

    VII. Summary


    Chapter 8 Plant Cytogenetics

    I. Physical and Chemical Constitution of Chromosomes

    II. Behavior of Chromosomes in Different Tissues

    III. Differentiation of Chromosome Segments

    IV. Numerical and Structural Variability of Chromosome Complement—Origin and Role

    V. Size and Morphology of Chromosomes in Evolution

    VI. Karyotype as an Aid in Taxonomy

    VII. Conclusion


    Chapter 9 Polytene Chromosomes in Studies of Gene Expression

    I. Introduction

    II. DNA Content of the Chromosome Band

    III. Genetic Equivalent of the Chromosome Band

    IV. Relation of Puffing to Gene Activity

    V. The Transcriptory Activity

    VI. Release of Chromosomal RNA to the Nuclear Sap

    VII. Puff RNA in the Cytoplasm

    VIII. Conclusions and Perspectives


    Chapter 10 Giant Chromosomes

    I. Structural Organization of Giant Chromosomes

    II. Metabolic Activities of Giant Chromosomes

    III. Giant Chromosomes from the View of Genome



    Part III Chromosomes-Pathology

    Chapter 11 Clinical Cytogenetics

    I. Trisomy

    II. Monosomy G

    III. Trisomy 18

    IV. Deletion-18 Syndromes

    V. B Deletion Syndromes

    VI. Trisomy 13

    VII. D-Deletion Syndromes

    VIII. C-Group Trisomies

    Chapter 12 Viruses and Chromosomes

    I. Introduction

    II. Types of Virus-Induced Chromosome Alterations

    III. Studies on the Mechanisms of Virus-Induced Chromosomal Alteration

    IV. Significance of Virus-Induced Chromosome Alterations

    V. Summary


    Part IV Mitosis and Meiosis

    Chapter 13 The Mitotic Apparatus

    I. Introduction

    II. Fine Structure of the Mitotic Apparatus

    III. Biochemistry of the Isolated Mitotic Appartus


    Chapter 14 Genome Separation Mechanisms in Prokaryotes, Algae, and Fungi

    I. Introduction

    II. Prokaryotes

    III. Introduction to Microtubules

    IV. Algae

    V. Fungi

    VI. Summary


    Author Index

    Subject Index

Product details

  • No. of pages: 590
  • Language: English
  • Copyright: © Academic Press 1974
  • Published: January 1, 1974
  • Imprint: Academic Press
  • eBook ISBN: 9780323145077

About the Editor

Harris Busch

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