The Cell Nucleus V2
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The Cell Nucleus, Volume II covers mainly the chromosomes, including its pathology. It also reviews the information onthe isolated mitotic apparatus highlighting on its chemistryand relevant morphology. This volume particularly discusses the mammalian chromosomes, the staining techniques, the kinetics of DNA replication in chromosomes, and the difference of meiotic chromosomes from mitotic chromosomes. It also presents studies on isolated mammalian metaphase chromosomes; chromosomes of birds and plants; as well as the polytene chromosomes of the two-winged insects, the Diptera. Furthermore, this volume describes the giant chromosomes. Lastly, the autosomal disorders, the abnormalities of sex development, and types of virus-induced chromosome alterations are explained to elucidate the pathology of chromosome.
Table of Contents
List of Contributors
Preface
Contents of Other Volumes
Introduction
Part I Chromosomes-General
Chapter 1 Mammalian Chromosomes
I. Introduction
II. DNA Content, Chromosome Number, and Chromosome Morphology
III. Sex Chromosomes
IV. Heterochromatin
V. Cytochemical Differentiation of Chromosomal Regions
VI. Somatic Cell Hybridization
VII. Chromosomes in Evolution
References
Chapter 2 The Human Cell Nucleus: Quinacrine and Other Differential Stains in the Study of Chromatin and Chromosomes
I. Perspectives on Human and Medical Cytogenetics
II. Human Chromosome Identification
III. Human Chromosome Polymorphisms
IV. Study of Chromosome Abnormalities
V. Chromosome Abnormalities in Malignancies
VI. Paternity Studies
VII. Parental Origin of Chromosome Abnormalities
VIII. Gene Mapping Using Chromosome Polymorphisms, Rearrangements,
and Somatic-Cell Hybridization
IX. Chromatin: Differentially Marked Regions on Autosomes and the Y in Interphase
X. Meiotic Chromosomes
XI. Chromosome Evolution and Banding
References
Chapter 3 Studies of Isolated Mammalian Metaphase Chromosomes
I. Introduction
II. Isolation of Metaphase Chromosomes
III. Chemical Composition of Metaphase Chromosomes
IV. Studies with Fractionated Metaphase Chromosomes
V. The Structure of Metaphase Chromosomes
VI. Conclusions
References
Chapter 4 The Kinetics of DNA Replication in Chromosomes
I. Introduction
II. The Replicon
III. The Replicon Series
IV. The Chromosome
V. Discussion
VI. Conclusions
References
Chapter 5 The Organization of Meiotic Chromosomes
I. Introduction
II. General Organization of DNA in Chromosomes
III. Special Features of Meiotic Chromosomes
IV. Relation of Chromosome Structure to Meiotic Chromosome Behavior
V. Summary and Conclusions
References
Chapter 6 Progress in Human Gene Mapping by Somatic Cell Hybridization
I. Introduction
II. Methodology and Rationale of Human Gene Mapping
III. Assignments of Genes to Human Chromosomes
IV. Regional Localization of Human Genes
V. Conclusion
References
Part II Chromosomes-Specific
Chapter 7 Chromosomes of Birds
I. Introduction
II. Phylogeny of Birds and Genome Size
III. Mitotic Chromosomes
IV. Meiotic Chromosomes
V. Heterochromatin
VI. Heteroploidy
VII. Summary
References
Chapter 8 Plant Cytogenetics
I. Physical and Chemical Constitution of Chromosomes
II. Behavior of Chromosomes in Different Tissues
III. Differentiation of Chromosome Segments
IV. Numerical and Structural Variability of Chromosome Complement—Origin and Role
V. Size and Morphology of Chromosomes in Evolution
VI. Karyotype as an Aid in Taxonomy
VII. Conclusion
References
Chapter 9 Polytene Chromosomes in Studies of Gene Expression
I. Introduction
II. DNA Content of the Chromosome Band
III. Genetic Equivalent of the Chromosome Band
IV. Relation of Puffing to Gene Activity
V. The Transcriptory Activity
VI. Release of Chromosomal RNA to the Nuclear Sap
VII. Puff RNA in the Cytoplasm
VIII. Conclusions and Perspectives
References
Chapter 10 Giant Chromosomes
I. Structural Organization of Giant Chromosomes
II. Metabolic Activities of Giant Chromosomes
III. Giant Chromosomes from the View of Genome
Organization
References
Part III Chromosomes-Pathology
Chapter 11 Clinical Cytogenetics
I. Trisomy
II. Monosomy G
III. Trisomy 18
IV. Deletion-18 Syndromes
V. B Deletion Syndromes
VI. Trisomy 13
VII. D-Deletion Syndromes
VIII. C-Group Trisomies
Chapter 12 Viruses and Chromosomes
I. Introduction
II. Types of Virus-Induced Chromosome Alterations
III. Studies on the Mechanisms of Virus-Induced Chromosomal Alteration
IV. Significance of Virus-Induced Chromosome Alterations
V. Summary
References
Part IV Mitosis and Meiosis
Chapter 13 The Mitotic Apparatus
I. Introduction
II. Fine Structure of the Mitotic Apparatus
III. Biochemistry of the Isolated Mitotic Appartus
References
Chapter 14 Genome Separation Mechanisms in Prokaryotes, Algae, and Fungi
I. Introduction
II. Prokaryotes
III. Introduction to Microtubules
IV. Algae
V. Fungi
VI. Summary
References
Author Index
Subject Index
Product details
- No. of pages: 590
- Language: English
- Copyright: © Academic Press 1974
- Published: January 1, 1974
- Imprint: Academic Press
- eBook ISBN: 9780323145077