The Bone and Mineral Manual

2nd Edition

A Practical Guide

Editors: Michael Kleerekoper Michael Kleerekoper Ethel Siris Michael McClung
Print ISBN: 9780120885695
eBook ISBN: 9780080470740
Imprint: Academic Press
Published Date: 11th August 2005
Page Count: 208
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80.95 + applicable tax
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Key Features

Brings together up-to-date bone and mineral metabolism methods in one easily, accessible volume Provides a quick reference for bone and mineral disorders Addresses problems likely to be seen at all ages, from the pre-term infant to the centenarian Ideal for practicing physicians, residents, medical students, and researchers


Bone biologists, osteologists, and cell biologists.

Table of Contents

  1. Indications for Bone Mass Measurement
  2. A Practical Guide to Bone Densitometry
  3. Laboratory Analyses Useful in the Diagnosis of Bone and Calcium Metabolic Disorders
  4. Biochemical Markers of Bone Remodeling
  5. Skeletal Imaging: Radiographs, CT, MRI
  6. Scintigraphy
  7. Hypocalcemia and Hypercalcemia in Neonates
  8. Preterm Infants with Fractures
  9. Rickets
  10. Osteogenesis Imperfecta
  11. Juvenile Osteoporosis
  12. Fibrous Dysplasia
  13. Optimizing Peak Bone Mass
  14. Bone Disorders Associated with Primary or Secondary Amenorrhea
  15. Nephrolithiasis
  16. Acute Spinal Cord Injury and Tramatic Brain Injury
  17. Reflex Sympathetic Dystrophy
  18. Evaluation of the Patient with Low Bone Density
  19. Calcium and Vitamin D
  20. Pharmacologic Therapy
  21. Nonpharmacalgic Prevention and Management of Falls and Fractures
  22. Osteoporosis in Men
  23. Steroid-Induced Osteoporosis
  24. Organ Transplantation
  25. Paget’s Disease
  26. Renal Bone Diseases
  27. Metastatic Bone Disease
  28. Osteomalacia
  29. High Bone Mass
  30. Hypercalcemia
  31. Primary Hyperparathyroidism
  32. Hypocalcemia
  33. Phosporous and Magnesium
  34. Principles of Patient and Family Education and Support
  35. Resources for Education and Support


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Academic Press
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About the Editor

Michael Kleerekoper

Michael Kleerekoper

Affiliations and Expertise

Professor of Internal Medicine and Section Chief, Division of Endocrinology, University of Toledo Medical School, Toledo, OH, USA

Ethel Siris

Ethel S. Siris, MD, is the Madeline C. Stabile Professor of Clinical Medicine in the Department of Medicine, College of Physicians and Surgeons of Columbia University, and the Director of the Toni Stabile Osteoporosis Center of the Columbia University Medical Center, New York-Presbyterian Hospital, all in New York, New York. She is a graduate of Radcliffe College, Harvard University, and received her medical degree from the College of Physicians and Surgeons of Columbia University. An endocrinologist, she works as a clinician, as a clinical investigator and as a medical educator, all in the area of metabolic bone diseases, including osteoporosis and Paget's disease of bone. In her career she has participated in research activities with bisphosphonates, selective estrogen receptor modulators (SERMS) and RANKL inhibitors. Dr. Siris served as the Medical Director of NORA, the National Osteoporosis Risk Assessment, a public health initiative and longitudinal study of osteoporosis that included over 200,000 postmenopausal women in the US. Most recently her research activity has focused both on risk factors for osteoporosis and treatment adherence with osteoporosis medications. Dr. Siris is the immediate past president of the National Osteoporosis Foundation and currently serves on the Board of Trustees of both the National Osteoporosis Foundation in the US and the International Osteoporosis Foundation. She is also a member and former vice chair of the Board of Directors of the Paget Foundation for Paget's Disease of Bone and Related Disorders. She has previously served on the Council of the American Society for Bone and Mineral Research and on the Endocrinologic and Metabolic Drugs Advisory Committee of the US Food and Drug Administration. She has published widely in the medical literature and is co-editor of the book, The Bone and Mineral Manual. Dr. Siris has been interviewed frequently on both television and radio and is often quoted in print media regarding osteop

Affiliations and Expertise

Professor of Clinical Medicine, Department of Medicine, College of Physicians and Surgeons of Columbia University; Director of the Toni Stabile Osteoporosis Center of the Columbia University Medical Center, New York-Presbyterian Hospital, New York, New York, USA

Michael McClung

Dr. Michael McClung is the founding director of the Oregon Osteoporosis Center. He graduated from Rice University in Houston and from the University of Texas Southwestern Medical School in Dallas. After his training in Internal Medicine at Parkland Hospital in Dallas, he completed a fellowship in Endocrinology at the National Institute of Health in Bethesda, Maryland. He then joined the faculty at the Oregon Health Sciences University, where he is an Associate Professor of Medicine. At OHSU, he founded a clinic devoted to the care of patients with disorders of bone and calcium metabolism that eventually grew into the Oregon Osteoporosis Center. In 1987, Dr. McClung joined the Department of Medical Education at Providence Medical Center where he is actively involved in the training of young physicians. He is board certified in both Internal Medicine and in Endocrinology and Metabolism, and is a fellow of the American College of Endocrinologists and the American College of Physicians. Dr. McClung is an internationally recognized expert in the fields of osteoporosis and bone density testing. His Center has been involved in many of the important clinical studies that resulted in the availability of the medications now used to treat osteoporosis and Paget's disease of bone. He has published more than 200 papers and book chapters, is co-editor of a book for clinicians about disorders of bone and mineral metabolism and is a member of the editorial boards for several journals in his field. Dr. McClung is widely known as an educator, translating clinical research information into practical strategies of evaluation and treatment for other physicians. He is an active member of multiple international societies focusing on bone diseases and their treatment. He serves as a member of the Council of Scientific Advisors for the International Osteoporosis Foundation, on the Scientific Advisory Board of the National Osteoporosis Foundation, and as a medical advisor for t

Affiliations and Expertise

Founding Director of the Oregon Osteoporosis Center; Associate Professor of Medicine, Oregon Health Sciences University, Portland, OR, USA