The Biology of the Pancreatic Cell - 1st Edition - ISBN: 9780762305476, 9780080877143

The Biology of the Pancreatic Cell, Volume 29

1st Edition

Editors: S.L. Howell
Hardcover ISBN: 9780762305476
eBook ISBN: 9780080877143
Imprint: Elsevier Science
Published Date: 15th April 1999
Page Count: 354
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Table of Contents

Preface (S.L. Howell). Section1 &Bgr;-CellCell Development, Replication, and Death. Developmental Biology of the &Bgr;-CellCell (J.M.W. Slack). Pancreatic &Bgr;-Cell Lines: Their Roles in-Cell Research and Diabetes Therapy (S.J. Persaud). &Bgr;-Cell Dysfunction and Death (D.L. Eizirik and A. Hoorens). Islet Proteins Implicated in Pathogenesis of Type 1 Diabetes Mellitus (M.R. Christie). Section II Cellular Mechanisms of Insulin Synthesis and Secretion. Insulin Gene Expression (K. Docherty). Proinsulin Processing and Insulin Storage (C. Wasmeier, J.W.M. Creemers, R.S. Jackson, and J.C. Hutton). Mechanism of Insulin Exocytosis (R. Regazzi). Section III Regulation of Insulin Secretion. Potentiators and Inhibitors of Insulin Secretion (B. Ahren). Signal Recognition: Glucose and Primary Stimuli (E. Van Schaftingen and F. Schuit). Ion Channel Signal Transduction in Pancreatic-Cells (A.S. Rajan and L. Aguilar-Bryan). Signal Transduction: Regulation of Insulin Secretion by Changes in Ca2+ Concentration and Action in Pancreatic &Bgr;-Cells (J. Henquin, J. Jonas, Y. Sato, P. Detimary, and P. Gilon). Roles of Phospholipids and Phospholipase Activiation in &Bgr;-Cell Function (S.A. Metz). Signal Transduction: Protein Phosphorylation and the Regulation of Insulin Secretion (P.M. Jones, S.J. Persaud, and T.E. Harris). Section IV Conclusion. Future Challenges in &Bgr;-Cell Research (S.L. Howell). Index.


Description

Preface (S.L. Howell). Section1 &Bgr;-CellCell Development, Replication, and Death. Developmental Biology of the &Bgr;-CellCell (J.M.W. Slack). Pancreatic &Bgr;-Cell Lines: Their Roles in-Cell Research and Diabetes Therapy (S.J. Persaud). &Bgr;-Cell Dysfunction and Death (D.L. Eizirik and A. Hoorens). Islet Proteins Implicated in Pathogenesis of Type 1 Diabetes Mellitus (M.R. Christie). Section II Cellular Mechanisms of Insulin Synthesis and Secretion. Insulin Gene Expression (K. Docherty). Proinsulin Processing and Insulin Storage (C. Wasmeier, J.W.M. Creemers, R.S. Jackson, and J.C. Hutton). Mechanism of Insulin Exocytosis (R. Regazzi). Section III Regulation of Insulin Secretion. Potentiators and Inhibitors of Insulin Secretion (B. Ahren). Signal Recognition: Glucose and Primary Stimuli (E. Van Schaftingen and F. Schuit). Ion Channel Signal Transduction in Pancreatic-Cells (A.S. Rajan and L. Aguilar-Bryan). Signal Transduction: Regulation of Insulin Secretion by Changes in Ca2+ Concentration and Action in Pancreatic &Bgr;-Cells (J. Henquin, J. Jonas, Y. Sato, P. Detimary, and P. Gilon). Roles of Phospholipids and Phospholipase Activiation in &Bgr;-Cell Function (S.A. Metz). Signal Transduction: Protein Phosphorylation and the Regulation of Insulin Secretion (P.M. Jones, S.J. Persaud, and T.E. Harris). Section IV Conclusion. Future Challenges in &Bgr;-Cell Research (S.L. Howell). Index.


Details

No. of pages:
354
Language:
English
Copyright:
© Elsevier Science 1999
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080877143
Hardcover ISBN:
9780762305476

About the Editors

S.L. Howell Editor

Affiliations and Expertise

School of Biomedical Sciences, King's College London, London, England