The Biology of the Laboratory Rabbit - 1st Edition - ISBN: 9780127421506, 9781483270319

The Biology of the Laboratory Rabbit

1st Edition

Editors: Steven H. Weisbroth Ronald E. Flatt Alan L. Kraus
eBook ISBN: 9781483270319
Imprint: Academic Press
Published Date: 28th October 1974
Page Count: 510
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The Biology of the Laboratory Rabbit is a compendium of papers that discusses the use of the rabbit as an experimental substrate in the scientific process. The collection describes normative biology, research utilization, and rabbit disease. These papers emphasize naturally occurring diseases which affect the value of the rabbit as a research tool. Some papers describe these effects and their impact for investigators engaged in laboratory experimental work on animal medicine. Other papers tackle the value of certain rabbit diseases as models of considerable interest in comparative medicine. Several papers discuss bacterial diseases, viral diseases, protozoal diseases, arthropod parasites, helminth parasites, neoplastic diseases, inherited diseases, nutritional diseases, metabolic, traumatic, mycotic, and miscellaneous diseases of the rabbit. One paper describes a number of diseases that man can acquire from domestic and laboratory rabbits. These include tularemia (which is endemic in wild rabbits and hares), plague (transmitted by fleas), listeriosis (rare in laboratory rabbit colonies), salmonellosis (from rabbit feces), and Pasteurella multocida (common in laboratory and domestic rabbits). The paper notes that laboratory and domestic rabbits are not a major health hazard. The compendium can benefit veterinarians, the medically-oriented investigator, the biologist, the medical and chemical researcher, and others whose work involve laboratory animal care.

Table of Contents

Chapter 1 Taxonomy and Genetics

I. Taxonomy and Geographical Distribution of Rabbit Populations

II. Origin and Domestication of the Rabbit

IIΙ. Genetics of the Rabbit

IV. Inbred Strains


Chapter 2 Colony Husbandry

I. Introduction

II. Sexual Behavior and Breeding

III. Feeds and Feeding Behavior

IV. Commercial Herd Management

V. Laboratory Management


Chapter 3 The Anatomy, Physiology, and the Biochemistry of the Rabbit

I. Introduction

II. Anatomy—New Zealand White Rabbit

III. Physiology

IV. Biochemistry

V. Hematology


Chapter 4 Basic Biomethodology

I. Introduction

II. Handling and Restraint

III. Sampling Techniques

IV. Methods of Compound Administration

V. Anesthesiology

VI. Specialized Research Techniques

VII. Euthanasia

VIII. Necropsy Procedures


Chapter 5 The Fetus in Experimental Teratology

I. Introduction

II. Summarized Cyclic and Embryological Phenomena

III. Summarized Laboratory Techniques for Observation and Evaluation

IV. Fetal Pathology and Anatomical Variation

V. Teratological Investigation

VI. Conclusions


Chapter 6 Specialized Research Applications: I. Arteriosclerosis Research

I. Introduction and Scope of the Review

II. History of the Use of Rabbits in Arteriosclerosis

III. Research

IV. Naturally Occurring Arteriosclerosis of Rabbits

V. Diet-Induced Atherosclerosis of Rabbits

VI. Regression of Cholesterol-Induced Atherosclerosis of Rabbits


Chapter 7 Specialized Research Applications: II. Serological Genetics

I. The Blood Group Antigens

II. The Transplantation Antigens


Chapter 8 Gnotobiology

I. Introduction

II. The Caesarian Concept

III. Hand Rearing

IV. Intestinal Flora

V. Sterility Testing

VI. Gnotobiotic Isolators and their Maintenance

VII. Microbiological Monitoring and Histological Evaluation

VIII. Research Utilization


Chapter 9 Bacterial Diseases

I. Introduction

II. Pasteurellosis

III. Tularemia

IV. Yersiniosis (Pseudotuberculosis)

V. Necrobacillosis

VI. Salmonellosis

VII. Tyzzer's Disease

VIII. Listeriosis

IX. Tuberculosis

X. Treponematosis

XI. Staphylococcosis

XII. Miscellaneous Bacterial Diseases


Chapter 10 Viral Diseases

I. Introduction

II. DNA Virus Infections

III. Diseases Caused by RNA Viruses

IV. Diseases Possibly of Viral Origin


Chapter 11 Protozoal Diseases

I. General Introduction

II. Sporozoa

III. Toxoplasmida

IV. Microsporida

V. Flagellates and Amoebae

VI. Organisms of Uncertain Classification


Chapter 12 Arthropod Parasites

I. Introduction

II. The Principal Arthropod Groups


Chapter 13 Helminth Parasites

I. Introduction

II. Natural Infections

III. Experimental Infections

IV. Conclusions


Chapter 14 Neoplastic Diseases

I. Introduction

II. Neoplasms of Oryctolagus sp.

III. Neoplasms of Sylvilagus sp.

IV. Neoplasms of Lepus sp.

V. Neoplasms Associated with Oncogenic Viruses

VI. Transplantable Neoplasms Used as Model Systems


Chapter 15 Inherited Diseases and Variations

I. Introduction

II. Conditions Controlled by Single (Mutant) Genes

III. Familial or Polygenic Conditions

IV. Sources of Rabbits with Inherited Diseases and Variations


Chapter 16 Nutrition and Nutritional Diseases of the Rabbit

I. Comparative Nutrition

II. Vitamins

III. Minerals

IV. Summary


Chapter 17 Metabolic, Traumatic, Mycotic, and Miscellaneous Diseases of Rabbits

I. Introduction

II. Pregnancy Toxemia

III. Shock Disease

IV. Pylorospasm

V. Mucoid Enteropathy

VI. Superficial Mycoses

VII. Deep Mycoses

VIII. Mastitis

IX.Ulcerative Pododermatitis (Sore Hocks)

X. Traumatic Vertebral Fracture (Traumatic Vertebral Dislocation, Paralysis of the Hindquarters, Broken Back)

XI. Moist Dermatitis

XII. Heat Prostration

XIII. Hair Balls

XIV. Plant Toxicosis

XV. Band Keratopathy

XVI. Pulmonary Emphysema

XVII. Extrauterine Pregnancy (Abdominal Pregnancy, Ectopie Pregnancy)

Chapter 18 Diseases of Public Health Significance

I. Introduction

II. Bacterial Diseases

III. Mycotic Diseases

IV. Viral Diseases

V. Rickettsial Diseases

VI. Protozoan Diseases

VII. Helminth Diseases

VIII. Arthropod Infestations


Author Index

Subject Index


No. of pages:
© Academic Press 1974
Academic Press
eBook ISBN:

About the Editor

Steven H. Weisbroth

Ronald E. Flatt

Alan L. Kraus

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