The Anterior Pituitary

The Anterior Pituitary

1st Edition - January 1, 1975

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  • Editors: A. Tixier-Vidal, Marilyn G. Farquhar
  • eBook ISBN: 9781483273945

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Ultrastructure in Biological Systems, Volume 7: The Anterior Pituitary presents the mechanisms involved in the release of adenohypophysial hormones. This book explores the morphological approach to fundamental aspects of pituitary cell biology. Organized into eight chapters, this book begins with an overview of how the ultrastructure of cellular organelles can yield valid criteria of identification. This text then discusses the cellular and subcellular localization of anterior pituitary hormones by immunoelectron microscopy. Other chapters consider the localization of possible receptor sites for hormonal messengers on anterior pituitary cells. This book discusses as well the in vitro systems that have undergone a significant development, which is the ultrastructure and function of dispersed anterior pituitary cells. The final chapter deals with the ultrastructure of pituitary tumors, which can be divided into two categories, namely, functional and nonfunctional, according to the presence or the absence in the host of hormonal hypersecretion signs. This book is a valuable resource for biochemists, endocrinologists, histologists, and pathologists.

Table of Contents

  • List of Contributors



    I. The Identification of the Pituitary Cells with Electron Microscopy

    II. The Contribution of Electron Microscopy to the Functional Exploration of the Anterior Pituitary


    Mechanisms Involved in the Release of Adenohypophysial Hormones

    I. Introduction

    II. The Release Process

    III. Summary



    Identification of Anterior Pituitary Cells by Immunoelectron Microscopy

    I. Introduction

    II. Materials and Methods

    III. Results

    IV. Discussion


    Localization of Hormones in the Pituitary: Receptor Sites for Hormones from Hypophysial Target Glands and the Brain

    I. Methods

    II. Estrogens

    III. Androgens

    IV. Progestins

    V. Glucocorticoids

    VI. Thyroid Hormones

    VII. TRH

    VIII. Discussion

    IX. Conclusions


    Structure and Function of the Anterior Pituitary and Dispersed Pituitary Cells. In Vitro Studies

    I. Introduction

    II. General Background

    III. Evaluation of in Vitro Systems

    IV. Studies on Dispersed Pituitary Cells

    V. In Vitro Studies on Follicular Cells: Their Role in Phagocytosis of Cells and Cell Debris

    VI. Summary


    Separation of Organelles and Cells from the Mammalian Adenohypophysis

    I. Introduction

    II. Isolation of Subcellular Organelles from Adenohypophysial Tissue

    III. Dissociation and Separation of Cells from the Rat Adenohypophysis

    IV. Summary


    Ultrastructure of Anterior Pituitary Cells in Culture

    I. Introduction

    II. The Secretion of Pituitary Hormones by the Anterior Pituitary in Culture

    III. Ultrastructural Data

    IV. Conclusion


    Ultrastructure of Pituitary Tumor Cells: A Critical Study

    I. Introduction

    II. Cytogenesis in Normal Pituitary

    III. General Features of Pituitary Tumors

    IV. Morphological Features of Pituitary Tumors

    V. Summary


    Subject Index

Product details

  • No. of pages: 298
  • Language: English
  • Copyright: © Academic Press 1975
  • Published: January 1, 1975
  • Imprint: Academic Press
  • eBook ISBN: 9781483273945

About the Editors

A. Tixier-Vidal

Marilyn G. Farquhar

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