The Alkaloids

The Alkaloids

Chemistry and Physiology

1st Edition - January 1, 1954

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  • Editors: R. H. F. Manske, H. L. Holmes
  • eBook ISBN: 9781483221915

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The Alkaloids: Chemistry and Physiology, Volume IV contains an account of the chemistry and biosynthesis of the various classes of isoquinolines. This book discusses the extraction and separation of the anhalonium alkaloids, other natural simple isoquinolines, and anhalonium isoquinolines. The location of the alkaloids in tissues of the cacti, monophenolic bases of the laudanosine type, and extraction of cactus alkaloids are elaborated in detail. This text also describes the several types of alkaloids such as protoberberine, aporphine, protopine, phthalideisoquinoline, and bisbenzylisoquinoline. The cularine, a-naphthaphenanthridine, erythrophleum, aconitum, and delphinium alkaloids are likewise included. This publication is recommended for chemists, specialists, and students interested in isoquinolines.

Table of Contents

  • Preface

    The Biosynthesis of Isoquinolines

    Simple Isoquinoline Alkaloids

    I. Introduction

    II. The Anhalonium Alkaloids

    III. Extraction and Separation of the Anhalonium Alkaloids

    IV. The Anhalonium Isoquinolines

    V. Structure and Synthesis of the Anhalonium Alkaloids

    VI. Other Natural Simple Isoquinolines

    VII. Pharmacology

    VIII. References

    Cactus Alkaloids

    I. Introduction

    II. Constitution and Occurrence

    III. Location of the Alkaloids in Tissues of the Cacti

    IV. Extraction of Cactus Alkaloids

    V. References

    The Benzylisoquinoline Alkaloids

    I. Introduction

    II. Papaverine

    III. Laudanosine

    IV. Monophenolic Bases of the Laudanosine Type

    V. Biogenesis of the Benzylisoquinoline Alkaloids

    VI. References

    The Protoberberine Alkaloids

    I. Introduction

    II. Occurrence

    III. Berberine

    IV. Canadine

    V. Palmatine

    VI. Shobakunine

    VII. Tetrahydropalmatine

    VIII. Jatrorrhizine and Columbamine

    IX. Corypalmine and Isocorypalmine

    X. Scoulerine

    XI. Sinactine

    XII. Cheilanthifoline

    XIII. Ophiocarpine

    XIV. Capaurine and Capauridine

    XV. Capaurimine

    XVI. Stylopine and Coptisine

    XVII. Corydaline

    XVIII. Corybulbine

    XIX. Isocorybulbine

    XX. Thalictrifoline

    XXI. Thalictricavine

    XXII. Nandinine

    XXIII. Worenine

    XXIV. Umbellatine

    XXV. Neprotine

    XXVI. Thalictrine

    XXVII. Coreximine

    XXVIII. References

    The Aporphine Alkaloids

    I. Introduction

    II. Glaucine

    III. Glaucentrine

    IV. Boldine

    V. Laurotetanine

    VI. N-Methyllaurotetanine

    VII. Dicentrine

    VIII. Actinodaphnine

    IX. Domesticine

    X. Nantenine

    XI. Phanostenine

    XII. Crebanine

    XIII. Corydine

    XIV. Isocorydine

    XV. Corytuberine

    XVI. Suaveoline

    XVII. Bulbocapnine

    XVIII. Laurepukine

    XIX. Isothebaine

    XX. Tuduranine

    XXI. Laureline

    XXII. Pukateine

    XXIII. Anolobine

    XXIV. Stephanine

    XXV. Roemerine

    XXVI. Anonaine

    XXVII. Other Aporphines

    XXVIII. References

    The Protopine Alkaloids

    I. Introduction

    II. Occurrence

    III. Cryptopine

    IV. Cryptocavine

    V. Protopine

    VI. Allocryptopine

    VII. Hunnemanine

    VIII. Cryptopalmatine

    IX. Corycavine

    X. Corycavamine

    XI. Corycavidine

    XII. References

    Phthalideisoquinoline Alkaloids

    I. Introduction

    II. Constitution

    III. Syntheses

    IV. Discovery, Isolation, and Properties

    V. Physiology and Pharmacology

    VI. References

    Bisbenzylisoquinoline Alkaloids

    I. Introduction

    II. Alkaloids Containing One Diphenyl Ether Linkage

    III. Alkaloids Containing Two Diphenyl Ether Linkages

    IV. Alkaloids Containing Three Diphenyl Ether Linkages

    V. References

    The Cularine Alkaloids

    I. Introduction

    II. Cularine

    III. Cularimine

    IV. Cularidine

    V. References

    α-Naphthaphenanthridine Alkaloids

    I. Introduction

    II. Occurrence

    III. Structure

    IV. Pharmacology

    V. References

    The Erythrophleum Alkaloids

    I. Isolation

    II. Properties of the Alkaloids

    III. Pharmacology

    IV. References

    The Aconitum and Delphinium Alkaloids

    I. Introduction

    II. The Chemistry of the Atisines

    III. The Chemistry of the Aconitines

    IV. The Monoester Alkaloids Derived from Methoxyl-Rich Amino Alcohols Analogous to the Aconines

    V. "Miscellaneous" Alkaloids Isolated from Aconitum and Delphinium Species

    VI. References

    Author Index

    Subject Index

Product details

  • No. of pages: 368
  • Language: English
  • Copyright: © Academic Press 1954
  • Published: January 1, 1954
  • Imprint: Academic Press
  • eBook ISBN: 9781483221915

About the Editors

R. H. F. Manske

Affiliations and Expertise

Dominion Rubber Research Laboratory, Guelph, Ontario

H. L. Holmes

Affiliations and Expertise

University of British Columbia Vancouver, Canada

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