Textbook of Neuro-Oncology

1st Edition

Authors: Mitchel Berger Michael Prados
Hardcover ISBN: 9780721681481
eBook ISBN: 9781437713251
Imprint: Saunders
Published Date: 6th October 2004
Page Count: 880


This new resource presents today's most comprehensive, multidisciplinary coverage of cancers of the central and peripheral nervous system. Experts in neurosurgery, neuroradiology, neuropathology, neuro-oncology, and all other relevant fields present well-rounded, in-depth, cutting-edge information on epidemiology, diagnosis, and treatment for each type of tumor entity. This practical organization allows readers to efficiently access complete clinical knowledge on any form of neurological cancer.

Key Features

  • Presents an outstanding review of state-of-the-art basic science, including epidemiology as well as molecular and cellular biology.
  • Describes the very latest approaches to diagnostic imaging and pathologic classification.
  • Covers the newest treatment techniques, from neurosurgery through radiation therapy · chemotherapy · neuro-interventional techniques · immunotherapy · and gene therapy, and discusses functional outcomes and clinical trial findings.
  • Explores all of the most challenging neurologic cancers that clinicians face, including meningiomas · chordomas and chondrosarcomas of the cranial base · benign and malignant peripheral nerve tumors · medulloblastomas · neurocutaneous syndromes · ependymomas · and malignant rhabdoid tumors.
  • Includes a thorough section on Pediatric Neuro-Oncology.
  • Offers more than 800 crisp clinical and pathological photos to facilitate diagnosis and treatment
  • Features a user-friendly full-color layout throughout for ease of reference.

Table of Contents

Part 1: Basic Essential Principles

Section A: Basic Science

Chapter 1: The Epidemiology of Brain Tumors

Chapter 2: Molecular and Cell Biology

Chapter 3: Animal Models

Section B: Diagnosis

Chapter 4: Diagnostic Imaging

Chapter 5: Pathologic Classification

Section C: Treatment Principles

Chapter 6: Neuro-Endocrinology

Chapter 7: Neurotology

Chapter 8: Neuro-Ophthalmology

Chapter 9: Surgical Strategies in the Management of Brain Tumors

Chapter 10: Basic Concepts Underlying Radiation Therapy

Chapter 11: Chemotherapy Principles

Chapter 12: Treatment Principles: Neuro-interventional Techniques

Chapter 13: Immunotherapy

Chapter 14: Gene Therapy

Chapter 15: Functional Outcomes

Chapter 16: Clinical Trials

Part 2: Tumor-Specific Principles

Section A: Intra-axial Tumors

Chapter 17: Diffuse Astrocytoma

Chapter 18: Anaplastic Astrocytoma

Chapter 19: Glioblastoma Multiforme

Chapter 20: Pilocytic Astrocytoma

Chapter 21: Pleomorphic Xanthoastrocytoma

Chapter 22: Subependymal Giant Cell Astrocytoma

Chapter 23: Oligodendroglial Tumors

Chapter 24: Mixed Gliomas

Chapter 25: Ependymal Tumors

Chapter 26: Choroid Plexus Tumors: Choroid Plexus Papilloma and Choroid Plexus Carcinoma

Chapter 27: Astroblastoma

Chapter 28: Gliomatosis Cerebri

Chapter 29: Chordoid Glioma of the Third Ventricle

Chapter 30: Mixed Neuronal- Tumors

Chapter 31: Neuronal Tumors

Chapter 32: Dysembryoplastic Neuroepithelial Tumor

Chapter 33: Pineocytoma

Chapter 34: Pineoblastoma

Chapter 35: Medulloblastoma (Infratentorial PNET)

Chapter 36: Adult Supratentorial Primitive Neuroectodermal Tumors

Chapter 37: Lipomatous Tumors<


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About the Author

Mitchel Berger

Mitchel S. Berger M.D., F.A.C.S., F.A.A.N.S. is the Berthold and Belle N. Guggenhime Professor and Chairman of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), and is an expert in the fields of neurosurgery and neuro-oncology. He also serves as Director of UCSF’s Brain Tumor Research Center. After graduating from Harvard University in 1974, Dr. Berger earned his medical degree from the University of Miami School of Medicine. He completed a clinical fellowship in neuro-oncology at UCSF, a fellowship in pediatric neurosurgery at the Hospital for Sick Children of the University of Toronto, and his neurosurgical residency at UCSF. In 1986, he became Assistant Professor of Neurosurgery at the University of Washington School of Medicine, after which he was named Associate Professor (1990) and Professor (1996). Dr. Berger has clinical expertise in treating adult and pediatric brain and spinal cord tumors. He is a pioneer of intraoperative brain mapping — a technique used to avoid functional areas of the brain during surgical resection of a tumor. His work has enabled surgeons to perform more extensive resection of tumor with less chance of producing sensorimotor or language deficit. Dr. Berger is a leader of translational research and is the Principal Investigator of the UCSF Brain Tumor Research Center’s Specialized Program of Research Excellence in neuro-oncology, funded by the National Cancer Institute. His specific research interests lie in identifying molecular markers related to the progression and prognosis of glial tumors, as well as the development of small-molecule therapeutic agents that can be administered directly to the brain via convection-enhanced drug delivery. During his distinguished career, Dr. Berger has served as President of the American Association of Neurological Surgeons, President of the Society of Neuro-Oncology, President of the North Pacific Society of Neurology, and Vice President o

Affiliations and Expertise

Kathleen M. Plant Distinguished Professor and Chairman, Department of Neurological Surgery; Director, Neurological Surgery Research Centers and Brain Tumor Research Center; Director, Brain Tumor Surgery Program, University of California, San Francisco, San Francisco, CA

Michael Prados

Affiliations and Expertise

Charles B. Wilson Endowed Chair, Department of Neurosurgery, Director, Clinical Neuro-Oncology Program, Program Member and Clinical Leader, Neuro-Oncology Program, UCSF Comprehensive Cancer Center, University of California-San Francisco, San Francisco, CA, USA