Textbook of Nephro-Endocrinology - 1st Edition - ISBN: 9780123738707, 9780080920467

Textbook of Nephro-Endocrinology

1st Edition

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Editors: Ajay Singh Gordon Williams
Hardcover ISBN: 9780123738707
eBook ISBN: 9780080920467
Imprint: Academic Press
Published Date: 19th December 2008
Page Count: 522
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The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.

Key Features

  • Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems
  • Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work
  • Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field


Researchers and clinicians in nephrology and endocrinology

Table of Contents

Part 1: The Kidney as an Endocrine Organ

Section 1: Erythropoietin
1.Erythropoientin: An Historical Overview of Physiology, Molecular Biology And Gene Regulation David R. Mole, Peter J. Ratcliffe

2.Erythropoiesis: The Role of Erythropoietin and Iron Herbert Lin

3.Extra-Hematopoietic Action of Erythropoietin Zheqing Cai, Gregg Semenza

4.Development of Recombinant Erythropoietin and Erythropoietin Analogues Iain Macdougall

5.Erythropoietin Disease States & Resistance Ajay K. Singh, Tejas Patel, Shona Pendse, Sairam Keithi-Reddy
Section 2: Vitamin D, PTH and Novel Regulators of Phosphate

6.Vitamin D and the Kidney: Introduction and Historical Perspective Ajay K. Singh, Tejas Patel

  1. Vitamin D: Molecular Biology and Gene Regulation Adriana Dusso, Alex J. Brown

  2. Molecular Biology of Parathyroid Hormone Peter A. Friedman

9.Endocrine Regulation of Phosphate Homeostasis Harald Jüppner
Section 3: Renin-angiotensin
10.Introduction and Historical Overview Joel Menard

11.Molecular Biology of Renin and Regulation of Its Gene Timothy L. Reudelhuber, Daniel F. Catanzaro

  1. Physiology and Regulation of the RAAS System Robert Carey, Shetal H. Padia

  2. The Renin Angiotensin Aldosterone System and the Kidney George Bakris, Benjamin Ko

  3. The Renin Angiotensin and the Heart
    Carlos Ferrario, Aaron Trask

  4. The Renin-Angrotensin blockade: Therapeutic Agents Domenic Sica
    Part 2: The Kidney as a Hormonal target Section 4: Anti-diuretic Hormone

  5. Vasopressin in the Kidney: Historical Aspects Jeffrey Sands, Lynn E. Schlanger

  6. Molecular Biology and Gene Regulation Carolyn Ecelbarger, Swasti Tiwari

  7. Vasopressin Antagonists in Physiology and Disease
    Tomas Berl, Robert W. Schrier

  8. Diabetes Insipidus and SIADH J Carlos Ayus, Michael Moritz

Section 5: The Atrial Natriuretic Peptides

  1. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis John C Burnett, Jr., Candace Lee

Section 6: Aldosterone
21.Introduction and Historical Overview John Coghlan, James Tait

22.Aldosterone Receptors and Their Renal Effects: Molecular Biology And Gene Regulation Celso Gomez-Sanchez, Elise P. Gomez-Sanchez, Mario Galigniana

  1. Aldosterone and Its Cardiovascular Effects Gail K Adler, Rajesh Garg

  2. Aldosterone Regulation William Rainey, Wendy B. Bollag, Carlos M. Isales
    Section 7: Endocrine Disorders in Renal Failure

  3. Insulin resistance
    Donald Simonson

  4. Growth hormone
    John Mahan

27.Sexual Dysfunction in Men and Women with Chronic Kidney Disease
Biff F. Palmer

28.Thyroid Status in Chronic Renal Failure Patients
Victoria Lim, Manish Suneja

29.Metabolic Acidosis of Chronic Kidney Disease Jeffrey A. Kraut, Glenn T. Nagami

30.Pregnancy and the Kidney
Ananth Karumanchi, Chun Lam


No. of pages:
© Academic Press 2008
19th December 2008
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Editor

Ajay Singh

Affiliations and Expertise

Clinical Chief, Renal Division, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

Gordon Williams

Affiliations and Expertise

Director, Center for Clinical Investigation, Brigham and Women's Hospital, Professor of Medicine, Harvard Medical School, Cambridge, MA, USA


"This well-written, relatively concise, and current book will find a home on the shelves of many nephrologists and endocrinologists. Because it is so readable, it should be useful for students, experts, and those in between. I know I will consult my copy on a frequent basis - an unusual event in this era of online material." --N Engl J Med, 2009

"All in all, this is a solid book that provides substantial up-todate information on endocrine aspects of the kidney. I will be glad to pull it down from my shelf rather than one of the true heavyweights to which I would previously have gone for this kind of reading." --Kidney International, 2009

"Written by multidisciplinary experts from several countries, this book is divided into 2 parts and 7 sections. A very useful volume. Each chapter is richly referenced." --Pediatric Endocrinology Reviews

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