Textbook of Nephro-Endocrinology

Textbook of Nephro-Endocrinology

1st Edition - December 19, 2008

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  • Editors: Ajay Singh, Gordon Williams
  • eBook ISBN: 9780080920467
  • Hardcover ISBN: 9780123738707

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The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.

Key Features

  • Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems
  • Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work
  • Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field


Researchers and clinicians in nephrology and endocrinology

Table of Contents

  • Part 1: The Kidney as an Endocrine Organ

    Section 1: Erythropoietin
    1.Erythropoientin: An Historical Overview of Physiology, Molecular Biology
    And Gene Regulation
    David R. Mole, Peter J. Ratcliffe

    2.Erythropoiesis: The Role of Erythropoietin and Iron
    Herbert Lin

    3.Extra-Hematopoietic Action of Erythropoietin
    Zheqing Cai, Gregg Semenza

    4.Development of Recombinant Erythropoietin and Erythropoietin Analogues
    Iain Macdougall

    5.Erythropoietin Disease States & Resistance
    Ajay K. Singh, Tejas Patel, Shona Pendse, Sairam Keithi-Reddy
    Section 2: Vitamin D, PTH and Novel Regulators of Phosphate

    6.Vitamin D and the Kidney: Introduction and Historical Perspective
    Ajay K. Singh, Tejas Patel

    7. Vitamin D: Molecular Biology and Gene Regulation
    Adriana Dusso, Alex J. Brown

    8. Molecular Biology of Parathyroid Hormone
    Peter A. Friedman

    9.Endocrine Regulation of Phosphate Homeostasis
    Harald Jüppner
    Section 3: Renin-angiotensin
    10.Introduction and Historical Overview
    Joel Menard

    11.Molecular Biology of Renin and Regulation of Its Gene
    Timothy L. Reudelhuber, Daniel F. Catanzaro

    12. Physiology and Regulation of the RAAS System
    Robert Carey, Shetal H. Padia

    13. The Renin Angiotensin Aldosterone System and the Kidney
    George Bakris, Benjamin Ko

    14. The Renin Angiotensin and the Heart
    Carlos Ferrario, Aaron Trask

    15. The Renin-Angrotensin blockade: Therapeutic Agents
    Domenic Sica
    Part 2: The Kidney as a Hormonal target
    Section 4: Anti-diuretic Hormone
    16. Vasopressin in the Kidney: Historical Aspects
    Jeffrey Sands, Lynn E. Schlanger

    17. Molecular Biology and Gene Regulation
    Carolyn Ecelbarger, Swasti Tiwari

    18. Vasopressin Antagonists in Physiology and Disease
    Tomas Berl, Robert W. Schrier

    19. Diabetes Insipidus and SIADH
    J Carlos Ayus, Michael Moritz

    Section 5: The Atrial Natriuretic Peptides

    20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis
    John C Burnett, Jr., Candace Lee

    Section 6: Aldosterone
    21.Introduction and Historical Overview
    John Coghlan, James Tait

    22.Aldosterone Receptors and Their Renal Effects: Molecular Biology
    And Gene Regulation
    Celso Gomez-Sanchez, Elise P. Gomez-Sanchez, Mario Galigniana
    23. Aldosterone and Its Cardiovascular Effects
    Gail K Adler, Rajesh Garg

    24. Aldosterone Regulation
    William Rainey, Wendy B. Bollag, Carlos M. Isales
    Section 7: Endocrine Disorders in Renal Failure

    25. Insulin resistance
    Donald Simonson

    26. Growth hormone
    John Mahan

    27.Sexual Dysfunction in Men and Women with Chronic Kidney Disease
    Biff F. Palmer

    28.Thyroid Status in Chronic Renal Failure Patients
    Victoria Lim, Manish Suneja

    29.Metabolic Acidosis of Chronic Kidney Disease
    Jeffrey A. Kraut, Glenn T. Nagami

    30.Pregnancy and the Kidney
    Ananth Karumanchi, Chun Lam

Product details

  • No. of pages: 522
  • Language: English
  • Copyright: © Academic Press 2008
  • Published: December 19, 2008
  • Imprint: Academic Press
  • eBook ISBN: 9780080920467
  • Hardcover ISBN: 9780123738707

About the Editors

Ajay Singh

Affiliations and Expertise

Clinical Chief, Renal Division, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

Gordon Williams

Affiliations and Expertise

Director, Center for Clinical Investigation, Brigham and Women's Hospital, Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

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