Key Features

Salient Features

    • Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs:
      • Drugs acting on inflammation
      • Drugs acting on respiratory system
      • Drugs acting on digestive system
      • Drugs acting on blood and blood-forming organs
      • Drugs acting on endocrine system

    • Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents
    • Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic
    • Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject
    • Covers the syllabi of majority of Indian universities

Table of Contents

Preface v

Acknowledgements vii

SECTION I Drugs Acting on Inflammation/Allergy 1

Chapter 1 Antihistamines 3

• Structure–Activity Relationship—H1 Receptor

Antagonists • Classification • Synthesis and Drug Profile

Chapter 2 Prostaglandins 46

• Functions of PGs • Biosynthesis • Synthesis

and Drug Profile

Chapter 3 Analgesics, Antipyretics, and NSAIDs 56

• Classification • SAR of Salicylates; Synthesis

and Drug Profile; SAR of p-Amino Phenol

Derivatives; SAR of 3,5-Pyrazolidine Diones;

SAR of Anthranilic Acid Derivatives;

SAR of Aryl Alkanoic Acid Derivatives;

SAR of Indole Acetic Acid Derivatives; SAR of Oxicams

SECTION II Drugs Acting on Respiratory System 107

Chapter 1 Expectorants and Antitussives 109

• Introduction to Respiratory System • Expectorants and

Antitussives • Classification • Synthesis and Drug Profile

Section III Drugs Acting on Digestive System 119

Chapter 1 Antiulcer Agents 121

• Classification • Synthesis and Drug

Profile • SAR of H2-Receptor Antagonists

Chapter 2 Antidiarrhoeals 137

• Synthesis and Drug Profile

SECTION IV Drugs Acting on Blood and Blood-Forming Organs 143

Chapter 1 Coagulants 145

• Classification • Anticoagulants;

Classification; Synthesis and Drug Profile

Chapter 2 Plasma Expanders 160

SECTION V Drugs Acting on Endocrine System 163

Chapter 1 Oral Hypogylcaemic Drugs 165

• Classification • Synthesis and Drug

Profile • SAR of Sulphonyl Ureas

Chapter 2 Steroids 192

• Steroid Nomenclature and Structure

• Proge


© 2009
Elsevier India
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