LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
α-Tertiary Amines en Route to Natural Products
- 1st Edition - January 14, 2021
- Authors: Abdul Hameed, Mariya Al-Rashida, Muhammad Raza Shah
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 2 2 6 2 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 3 3 6 8 - 9
α-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteα-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the α,α-disubstituted α-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, α-amino acids based natural products, α amino acid based natural products and Tetrodotoxin.
This book is ideal for chemists working in the area of organic synthesis, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis.
- Outlines synthetic strategies for natural products bearing α-tertiary amines and α,α-disubstituted α-amino acid motif
- Describes multistep synthetic routes that highlight key steps
- Covers asymmetric and diastereoselective synthetic approaches towards targeted natural products
- Illustrates multistep synthetic routes related to -amino acids based natural products and -amino acids based natural products
Researchers working in the area of organic synthesis and natural products, especially those who are involved in the development of new, efficient and novel methodologies for natural product synthesis
1. Introduction: α,α-Disubsituted α-Amino Acids
2. Altemicidin
3. Amathaspiramide(A-F)
4. Kaitocephalin
5. Lactacystin
6. Salinosporamide
7. Manzacidins (A, C)
8. Sphingofungins (E, F) Synthesis
9. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid)
10. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin
11. Introduction: α,α-Disubsituted α-Amino Acids
12. Altemicidin
13. Amathaspiramide(A-F)
14. Kaitocephalin
15. Lactacystin
16. Salinosporamide
17. Manzacidins (A, C)
18. Sphingofungins (E, F) Synthesis
19. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid)
20. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin
- No. of pages: 240
- Language: English
- Edition: 1
- Published: January 14, 2021
- Imprint: Elsevier
- Paperback ISBN: 9780128222621
- eBook ISBN: 9780128233689
AH
Abdul Hameed
Dr. Abdul Hameed Dr. Abdul Hameed completed his PhD in Organic Chemistry from The University of Nottingham, UK. He worked in the area of natural products synthesis. He was a post-doc fellow in Max-Planck Institut für Polymerforschung, Germany in synthetic division headed by Prof. Dr. Klaus Müllen. There he worked on the functionalization of adenylyl cyclsase inhibitors via chemical methods to conjugate them with monoclonal antibody to study their biological potential in Regulatory T cells (Treg). His current research interests are including the development of novel methodologies, their utilization in natural products synthesis, the synthesis heterocyclic compound compounds to evaluate their biological potential.
Affiliations and expertise
Department of Chemistry, University of Sahiwal, Sahiwal 57000, PakistanMA
Mariya Al-Rashida
Dr. Mariya al-Rashida is a synthetic chemist and has expertise in the area of organic synthesis. She completed Ph.D. in chemistry from the Institute of Chemistry, University of the Punjab, Lahore, Pakistan in 2011. Her area of expertise is synthetic and computational medicinal chemistry. She is currently working towards the synthesis of metalloenzyme inhibitors (carbonic anhydrase, and ecto-nucleotidases). She is an Associate Professor and Chairperson of the Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan. She has published more than 60 research articles with a cumulative Impact Factor > 150 in various peer review international journals. She has been the recipient of many awards including the prestigious CSP Gold Medal Award for Chemist Under 40.
Affiliations and expertise
Department of Chemistry, Forman Christian College, Lahore, PakistanMS
Muhammad Raza Shah
Muhammad Raza Shah is a full professor at the International Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan. He is also the Head of the Center for Bioequivalence Studies and Clinical Research. He is a recipient of several awards, including the Tamgha-i-Imtiaz Award from the President of Pakistan, the Salam Prize, the Professor Atta ur Rahman Gold Medal, and the Dr M Raziuddin Siddiqi Prize, by the Pakistan Academy of Sciences, for scientists under 40 years of age, in the field of chemistry. Professor Shah has authored six books and edited four books, in addition to contributing over 350 peer-reviewed journal papers. One of his authored books was declared as best book of 2017 by the Government of Pakistan’s Higher Education Commission.
Affiliations and expertise
Professor, International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry University, Karachi, PakistanRead α-Tertiary Amines en Route to Natural Products on ScienceDirect