T Cell Subsets, Volume 83
1st Edition
Cellular Selection, Commitment and Identity
Table of Contents
Lineage Commitment and Developmental Plasticity in Early Lymphoid Progenitor Subsets The CD4/CD8 Lineage Choice: New Insights into Epigenetic Regulation During T Cell Development CD4/CD8 Coreceptors in Thymocyte Development, Selection, and Lineage Commitment: Analysis of the CD4/CD8 Lineage Decision Development and Function of T Helper 1 Cells Th2 cells: Orchestrating Barrier Immunity Generation, Maintenance, and Function of Memory T. Cells An Integrated Model of Immunoregulation Mediated by Regulatory T Cell Subsets
Description
This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.
T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers
Readership
Immunologists and infectious disease researchers
Details
- No. of pages:
- 304
- Language:
- English
- Copyright:
- © Academic Press 2004
- Published:
- 20th May 2004
- Imprint:
- Academic Press
- eBook ISBN:
- 9780080551951
- Hardcover ISBN:
- 9780120224838
Ratings and Reviews
About the Serial Editors
Frederick Alt Serial Editor
Affiliations and Expertise
Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA
About the Serial Volume Editors
H. Cantor Serial Volume Editor
Affiliations and Expertise
Dana Farber Cancer Institution, Boston, Massachussetts, U.S.A.
Laurie Glimcher Serial Volume Editor
Affiliations and Expertise
Harvard School of Public Health, Boston, Massachussetts, U.S.A.