Systems Biology and Its Application in TCM Formulas Research

Systems Biology and Its Application in TCM Formulas Research

1st Edition - February 16, 2018

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  • Editor: Wei-Dong Zhang
  • Paperback ISBN: 9780128127445
  • eBook ISBN: 9780128127452

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Description

Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine.

Key Features

  • Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases
  • Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology
  • Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research

Readership

Systems biology researchers; TCM researchers; graduate students; pharmacologists

Table of Contents

  • Part I Modern Research Strategies and Methodologies of Traditional Chinese Medicine
    1. Strategies on the Modern Research System for Traditional Chinese Medicine
    2. Theories and methodology of the study on pharmacodynamics material basis of Traditional Chinese Medicine
    3. Application of systems biology in the research of Traditional Chinese Medicine genome of yeast
    4. Applications of Network Pharmacology in the Study of TCM Formulas
    5. Applications of Intestinal Flora in the Study of TCM Formulas
    6. A New Weapon of Traditional Chinese Medicines Research: Connectivity Map

    Part II Modern Research of Shexiang Baoxin Pill (SBP)
    7. Identification of Multiple Constituents in Shexiang Baoxin Pill by LC Coupled with DAD-ESI-MS-MS
    8. Analysis of the Bioactive Constituents of Shexiang Baoxin Pill by Serum Pharmacochemistry
    9. Quality Standard for Shexiang Baoxin Pill
    10. Pharmacokinetic Study of Shexiang Baoxin Pill
    11. Metabolomic study of Shexiang Baoxin Pill
    12. Network Pharmacology Study of Shexiang Baoxin Pill

Product details

  • No. of pages: 380
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: February 16, 2018
  • Imprint: Academic Press
  • Paperback ISBN: 9780128127445
  • eBook ISBN: 9780128127452

About the Editor

Wei-Dong Zhang

Dr. Weidong Zhang obtained his BSc and Master degree in Natural Medicinal Chemistry from the Second Military Medical University in 1988 and 1991, respectively. He received his PhD in Natural Medicinal Chemistry from the Shanghai Institute of Pharmaceutical Industry (1998), under the supervision of Professor HuiTing Li. He is currently a professor of the Shanghai University of Traditional Chinese Medicine and Second Military Medical University. His research mainly focuses on Chinese medicine formulas, isolation, structural identification and modification, total synthesis, and structure–activity relationships of bioactive natural products. Dr. Zhang has published more than 500 peer-reviewed research papers and reviews.

Affiliations and Expertise

Professor, Shanghai University of Traditional Chinese Medicine and Second Military Medical University, Shanghai, China.

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